46 results about "Molecular stability" patented technology

This invention relates to the field of recombinant antibody technology. It provides novel recombinant IgY antibody constructs for diagnostic and therapeutical applications. The bivalent antibody constructs display a heterotetrameric or homodimeric format stabilized by disulfide bonds. The constant heavy chain domains C_H2-C_H4 are partly or completely of avian origin, whereas the V_H, V_L, C_L, and C_H1 domains as well as the hinge region may be of avian origin or derived from any other species. The invention allows to combine the advantages of IgY antibodies with those of established mammalian monoclonal antibodies. IgY antibody constructs comprising nonglycosylated IgY constant heavy chain domains allow to reduce unwanted interactions with C-type lectins, e.g., in human sera. Furthermore, chimeric IgY antibody containing mammalian V_H, V_L, C_L, and C_H1 domains as well as a mammalian hinge region provide a higher molecular stability than IgY antibodies in acidic conditions and, thereby, are especially suited for peroral therapeutic applications.

The invention relates to a mixed absorbing agent for catching or separating carbon dioxide from gas mixture, which mainly comprises the components by weight percent: 10-50wt% of 3-dimethyl amino-1-propyl alcohol, 5-10wt% of primary amine and/or secondary amine and balance water. The absorbing agent has high solubility for low-pressure carbon dioxide, good desorbing effect, lower reaction heat of absorption reaction and lower energy consumption for catching or separating the carbon dioxide; and as the 3-dimethyl amino-1-propyl alcohol is a tertiary amine and has high boiling point and better molecular stability than primary amine and secondary amine, so that the mixed absorbing agent can greatly reduce the degradation consumption of solvent in the using process, has good catching effect, and can be used for catching or separating the carbon dioxide in various gas mixtures such as flue gas, refinery gas, natural gas, synthesis gas, shift gas, hydrogen preparation gas and the like.

The invention provides polysubstituted silicon heterocyclic hexadiene as shown in formula I, wherein R<1> and R<2> are identical or different and represent alkyl or aryl; R<3> represents hydrogen, aldehyde group, ketone group, ester group and phosphate group; R<4> represents alkyl and aryl; R<5> represents hydrogen, alkyl, alkenyl and aryl; and R<6> represents alkyl and aryl. The compound which has high molecular stability is an important precursor of organic conducting material and organic photoelectric material. The invention adopts the insertion ring-enlargement reaction between end group alkyne and silicon heterocyclic butane under the catalysis of palladium to make the polysubstituted silicon heterocyclic hexadiene at high yield. The method, being scientific and reasonable, has easily obtained raw material, wide application range, high separation yield and simple experimental equipment and operation, and is convenient for industrial production.

The invention belongs to the field of chemical materials, and particularly relates to an absorption solvent which is used for collecting or separating carbon dioxide from gas mixture or liquefied gas.The solvent comprises 3-dimethylamino-1-propanol (abbreviated as DMA1P) with a content range of 10-70 wt% and other components with a total content range of 30-90 wt%, wherein, the other components comprise one or more of monoethanol amine, n-propanol amine, hydroxyethyl piperazine, water, physical solvent, inorganic salt or auxiliary agent. The solubility of carbon dioxide in 3-dimethylamino-1-propanol is high and the deabsorption effect is good; simultaneously the reaction heat of the absorption reaction is lower and the energy consumption for collecting or separating carbon dioxide is lower; meanwhile, 3-dimethylamino-1-propanol is a tertiary amine, the carbon chain is a linear chain, six-membered ring with better molecular stability can be formed through hydrogen bond, and the degradation loss of solvent in the use process can be reduced substantially.

The invention discloses an organic compound containing a xanthene structure and an application of the organic compound. The structural general formula of the compound is shown in the general formula (1). The compound is high in glass transition temperature and molecular stability, proper in HOMO and LUMO energy level, and relatively high in Eg. Through device structure optimization, the photoelectric property of an OLED device is improved and the service life of the OLED device is prolonged.

The invention provides a composition for increasing fertilizer absorption and utilization rate and application thereof. The composition comprises orange essential oil, an emulsifier and an organic solvent, wherein the orange essential oil comprises, by mass percentage, 10-30% of grapefruit essential oil and 50-70% of orange peel essential oil. A method for increasing the fertilizer absorption andutilization rate includes: adding the composition into fertilizer, evenly mixing, and applying the fertilizer to crops. The composition has the advantages that the orange essential oil in the composition can increase molecular stability in humic acid, the problems of alginic acid fertilizer gas expansion and solid fertilizer moisture absorption are solved, the orange essential oil can carry fertilizer components to fast penetrate leaves to enter the bodies of plants, and the absorption and utilization rate of humic acid fertilizer, alginic acid fertilizer, amino acid fertilizer, oligosaccharide fertilizer and fish protein fertilizer can be increased.

The invention provides a high molecular material thermal stability tester and belongs to the field of testing of high molecular stability. The high molecular material thermal stability tester comprises a heating device, a container and an electronic control system. The heating device comprises a heating body and a vibrating table, the heating body and the vibrating table are electrically connected with the electronic control system, and the heating body is arranged on the vibrating table; the container is internally provided with a plurality of test tubes and sample grooves, the sample grooves are fixedly connected with the container, the sample grooves are provided with mesh holes, and the interiors of the sample grooves are communicated with the interior of the container through the mesh holes. According to the high molecular material thermal stability tester, the sample grooves are utilized to fix the test tubes, the test tubes are prevented from waggling in the container, both hands of an experimenter are liberated, the test tubes are heated in the sample grooves, and meanwhile the vibrating table conducts vibration continuously, so that a solution in the container and materials in the test tubes are heated uniformly, the heating effect is good, and accuracy of tested thermal stability data and the result is high.

The invention relates to an acylated derivative of mogrolic acid. The structure of the acylated derivative is shown as a formula (I) or a formula (II), wherein R is acyl. Hydroxyl groups in molecules of several kinds of mogrolic acid (mogrolic acid A and mogrolic acid D) containing hydroxyl groups are acylated, and on the premise that the pharmacological activity of the hydroxyl groups is not changed, the molecular structure is modified, so that the solubility is improved. Besides the solubility is improved, the molecular stability of the hydroxyl acylated mogrolic acid is improved, the residence time of the hydroxyl acylated mogrolic acid in a living body can be effectively prolonged, and the bioavailability is improved. The inventor also finds that the acylated derivative of mogrolic acid provided by the invention has excellent anti-inflammatory activity, especially a maleic acid acylated derivative of mogrolic acid.

The invention relates to an anti-shrinkage modified EVA foam shoe material. The material comprises 40-43 parts of Formosa Plastics 7470, 5-6 parts of Formosa Plastics 7350, 6-8 pieces of Taiju 3312, 7-8 parts of Dow 3745, 10-12 an anti-shrinkage agent 203#, 1-1.5 parts of zinc oxide, 6-8 parts of an anti-wear agent, 2-3 parts of a filler, 0.3-0.5 part of an activator, 0.6-0.7 part of a cross-linking agent, 2-2.5 parts of a foaming agent and 3-4 parts of titanium dioxide. High-melting point and low-melt strength components are selected, so the product maintains molecular stability during use, the strain force required by the shrinkage deformation of the product is improved, the material has a low melt strength when the melting point of the material is reached in the production process of the product, the resistance to volume expansion is reduced, and the residual stress of the product after molding is reduced, thereby the shrinkage tendency is reduced, and the problem of heat shrinkagedeformation of the finished product is solved while ensuring "light, flexible, soft and elastic" basic characteristics.

The invention discloses preparation and an application of a novel umbrella-type light-emitting material with a pyrrole structure. The umbrella-type organic compound with the pyrrole structure has goodmolecular stability, a prepared OLED (organic light-emitting diode) device has superior photoelectric properties, high heat stability, low driving voltage and high efficiency, the service life of thedevice is prolonged, and the requirements of device manufacturers can be effectively met. The structure of the organic compound is as shown in a general formula (1), Ar is indicated as substituted orunsubstituted C6-60 aryl and 5-60 heterogeneous aryl containing one or more heteroatom, and the heteroatoms are nitrogen, oxygen or sulfur.

The invention relates to an organic aromatic amine luminescent material containing a seven-membered ring, and belongs to the technical field of organic photoelectric materials. An organic compound with organic aromatic amine having the seven-membered ring as a core structure is used for an OLED device as a light-emitting layer or an electron transfer layer material. The material has good molecularstability, and the prepared OLED device has superior photoelectric performance, high thermal stability, low driving voltage and high efficiency. The service life of the device can be prolonged, and the requirements of device manufacturers can be met.

The invention discloses a recombinant feline herpesvirus type 1 gB-gD protein and application thereof. The recombinant feline herpesvirus type 1 gB-gD protein comprises a first protein having a sequence as shown in SEQ ID NO:2 and/or a second protein having a sequence as shown in SEQ ID NO:6. A vaccine comprises the recombinant feline herpesvirus type 1 gB-gD protein and a pharmaceutically acceptable carrier. The recombinant feline herpesvirus type 1 gB-gD protein provided by the invention is long in half-life period, high in molecular stability, capable of forming a dimer, especially a heterodimer, strong in immunogenicity, capable of being prepared in a bioreactor large-scale serum-free suspension culture mode through a mammalian cell expression system, high in expression level and good in protein immunogenicity; and the prepared vaccine also has the advantages of easy quality control, batch-to-batch stability, low production cost and the like.

The invention discloses a pyrrolopyrrole organic semiconductor material containing free radicals, a preparation method and application thereof and belongs to the technical field of photoelectric materials. The preparation method comprises the following steps: mixing a pyrrolopyrrole halogenated derivative with a monomer I, or mixing a pyrrolopyrrole organic tin compound and a monomer I' to obtaina pyrrolopyrrole organic semiconductor material; enabling the pyrrolopyrrole organic semiconductor material to react with an oxidant to obtain the pyrrolopyrrole organic semiconductor material containing the free radicals. The preparation method disclosed by the invention is simple in synthesis routine and easy in synthesis. The pyrrolopyrrole organic semiconductor material containing the free radicals prepared by the invention has the advantages that the electron mobility is high, the molecular stability is good, the absorption intensity is high, the absorption waveband is narrow, the absorption wavelength reaches a near-infrared waveband, and the pyrrolopyrrole organic semiconductor material containing the free radicals can be used as a free-radical material of devices such as near-infrared and narrowband photoelectric detectors and organic field effect transistors.

The invention discloses a low-dielectric and low-dielectric-loss halogen-free resin composition, a prepreg and a laminated board. The halogen-free resin composition is made from, by weight, 100 partsof epoxy resin, 2-45 parts of a double-deck silsesquioxane curing agent, 10-50 parts of cyanate modified polyphenyl ether resin, 10-25 parts of benzoxazine resin, and 0.001-5 parts of an accelerator.A high-Tg resin material excellent in dielectric property is obtained through graft copolymerization of the silsesquioxane curing agent with a special structure, after curing, the resin material has higher molecular stability and lower chain-segment motion ability, and thus the metal clad laminated board prepared from the resin is more excellent in dielectric property, heat resistance, mechanicalproperty and moisture absorption resistance and the like.

The present invention relates to methods and compositions for enhancing folding and stability of biological molecules. In particular, the present invention relates to methods and compositions for identifying biological molecules with enhanced stability. The present invention further relates to host cells that confer enhanced stability to biological molecules expressed therein.

The invention discloses a polymeric dispersing agent for textile dyes and a preparation method of the polymeric dispersing agent in the technical field of fine chemical engineering. The preparation method of the polymeric dispersing agent for the textile dyes comprises the following steps that step 1, 10-30 parts of butyl methacrylate is added into a reactor of 60-80 DEG C; step 2, 4-6 parts of acrylic acid and 1 part of butyl methacrylate are mixed and added into another dropping funnel, an initiator is added, a reaction is performed for 2 hours; 4-6 parts of titanium sulphate is put into thereactor, the initiator is poured into the reactor through the funnel and is slowly stirred; step 3, substances after the reaction is evaporated to obtain a solid substance, the solid substance is added into the reactor, and 20-60 parts of water is added to form an aqueous solution; through stearamide and higher alcohols which are added in the prepared materials, while the own molecular activity is improved, the molecular stability of the butyl methacrylate in the mixed solution is also improved.

The invention discloses an aromatic amine compound with the structural formula I as shown in the specification. The compound has relatively high glass transition temperature and molecular stability, has low light absorbance and high refractive index in the field of visible light, and can effectively enhance the light extraction efficiency of OLED devices and increase the visual angle when appliedonto CPL layers of the OLED devices.

The invention relates to an organic photoelectric material with a boron bridged 2,2'-dithiophene structure and an application of the organic photoelectric material, and belongs to the field of organicphotoelectric materials. According to the organic photoelectric material provided by the invention, boron bridged 2,2'-dithiophene is adopted as a parent body, so that the molecular stability is greatly improved, the electron affinity and conductivity are improved, and the transmission of electrons is facilitated; aromatic amines with good hole transmission properties are combined, so that the photoelectric material with bipolar transmission capability is formed, the transmission of holes and electrons in a light-emitting layer is balanced, and the luminous efficiency is greatly improved; theorganic photoelectric material containing the boron bridged 2,2'-dithiophene structure provided by the invention has a space structure of a rigid trapezoidal plane structure, so that the molecular potential barrier is reduced, and the electron affinity is improved; and the organic photoelectric material is used as a light-emitting material of an organic light emitting diode (OLED) light-emittingdevice, the produced OLED device has the effect characteristics of high brightness, high efficiency and a low voltage.

The present invention is based on the application of heating resistors by a temperature regulation circuit in certain points of the catalyzer so that this comes into operation in the least time possible, reducing most of the amount of low molecular stability or environmentally harmful substances. Likewise, little tumult are added to each monolith duct to raise exhaust gas turbulence and increase the contact between the reduction and oxidation agent, whether it be platinum, palladium and rhodium.

The invention relates to a nucleic acid delivery system as well as a preparation method and application thereof. The nucleic acid delivery system is nanoparticles formed by entrapping nucleic acid by taking polyhydroxyalkanoate and an amine material as carriers. According to the invention, the polyhydroxyalkanoate compounded amine material is creatively used as a carrier for entrapment of nucleic acid, the amine material is combined with nucleic acid molecules, and the positive electricity provided by the amine material can improve the loading efficiency of nucleic acid and improve the cellular uptake efficiency of nucleic acid; wherein the polyhydroxyalkanoate has good biodegradability and biocompatibility, and can protect the molecular stability of the nucleic acid in the delivery process, so that the nucleic acid is prevented from being degraded by nuclease and lysosome, the cellular uptake efficiency of the nucleic acid is increased, and the release time of the nucleic acid is prolonged. The finally prepared nucleic acid delivery system has good nucleic acid entrapment capacity, can effectively deliver nucleic acid drugs into cells, and has the advantages of high transfection rate and low cytotoxicity.