10 results about "Neuroregulation" patented technology

The present disclosure is directed to a bio-feedback sensor in combination with AI and ML that can be implemented to optimize neuromodulation parameters for the management of a medical condition such a type II diabetes. The bio-feedback obtained by the sensors is optimized by the ML tools to predict and recommend the upregulation or downregulating the neuroregulators to modulate treatment. The algorithms could also learn to sense a life-threating pathological state, or bio-chemical imbalance, and in the case of diabetes a life-threating low blood sugar level the system overrides to stimulate the target fibers that control organs to regulate blood glucose levels.

The utility model relates to medical equipment technical field, concretely for based on patient active trigger and multimode feedback's upright tilt experiment safety control system, including patient trigger module, operator control module, collaborative feedback control module and tilt bed actuating mechanism. The patient can through wireless handheld button active trigger tilt bed lay flat, and button is equipped with long press identification, vibration feedback and low power prompt function. Control module according to patient signal, operator response and vital sign monitoring result, according to preset priority logic execution fast or slow lay flat, and support graded early warning and countdown interaction. The system is also provided with emergency stop rope and identity verification mechanism, and the operation safety is improved. The system can be widely applied to the tilt test scene such as neuroregulatory syncope screening, postural hypotension diagnosis, has the advantages of responding in time, high safety, good man-machine cooperation.

The application discloses a pet nutrition composition based on intestinal-brain axis regulation and application thereof, and the composition comprises 5-20% of probiotics, 10-25% of prebiotics, 2-10% of neurotransmitter precursors, 5-15% of anti-inflammatory and neurotrophic factors, 1-10% of plant extracts and the rest of carriers. The application remolds intestinal microecology by the synergy of probiotics and prebiotics, promotes the synthesis of 5-hydroxytryptamine and dopamine by neurotransmitter precursors, exerts the neuroprotective and anti-inflammatory effects by omega-3 fatty acids, vitamin B group and magnesium elements, realizes the anti-anxiety and tranquilizing effects by L-theanine, chamomile and lavender extracts, and forms a regulation link of multi-target point synergistic intervention of intestinal-brain axis. According to animal experiment verification, the application can significantly improve the anxiety behavior of pets, improve the content of fecal short-chain fatty acids, remodel the intestinal flora structure, and realize the synergistic effect of 'intestinal health-nerve regulation-behavior improvement'.

Embodiments of a method for treating a patient suffering from chronic pain are described. A source location of chronic pain in a patient is first identified. A regional anaesthetic is then used to temporarily block selected nerves to confirm the source location and identify a target nerve. An electrode array of a neuromodulation apparatus is then implanted in the patient over the target nerve, such as just under the stratum corneum, and the neuromodulation apparatus is then used to stimulate the electrode array to create a long term conduction block that provides persistent pain relief to the patient.

This invention discloses a zinc-quercetin nanocomposite, its preparation method, and its pharmaceutical applications, belonging to the field of bionanomaterials technology. This nanoparticle employs a carrier-free self-assembly strategy, directly forming a structurally stable nanocomposite by combining the natural flavonoid quercetin with zinc ions through metal-organic coordination bonds. This technology effectively overcomes the inherent defects of poor water solubility and low bioavailability of quercetin monomers, resulting in a nanocomposite with good water solubility and physiological stability. Simultaneously, zinc ions, as a key trace element for neuroregulation, can intervene in pain transmission pathways to alleviate pain; quercetin exerts a long-lasting anti-inflammatory and analgesic effect by continuously scavenging reactive oxygen species and inhibiting the release of inflammatory factors in damaged nerves or inflammatory sites. The two work synergistically in the lesion microenvironment, achieving the prevention and efficient, safe treatment of chronic pain. The preparation process is extremely simple, requiring no complex carriers, and has broad prospects for clinical translation and application.

This invention discloses a method for mind-body integration and emotional empowerment based on vocal training, belonging to the field of mind-body healing and personal growth technology. This method uses vocal production, breath control, and singing expression as its core medium, integrating positive psychology, developmental educational psychology, and neuroscience theories of neuroregulation. Through breath preparation, step-by-step vocal training, emotional anchoring, immersive singing expression, and periodic review, it achieves emotional relief, stress release, enhanced self-awareness, and increased inner energy in users. This method is repeatable, easy to teach and implement, and applicable to various scenarios of self-growth, emotional management, and mind-body healing. It can systematically help individuals gain self-insight, heal their inner selves, and enhance life energy through vocal music, possessing strong practicality and promotional value.

The present application relates to the technical field of medical equipment, specifically a nerve regulation multi-modal anti-depression therapeutic instrument, which is used to solve the problem that the prior art usually only involves a single treatment method for depression treatment. The present application dynamically adjusts multi-modal data, including electroencephalogram signals, stimulation frequency or intensity of transcranial magnetic stimulation, stroboscopic frequency, light intensity, light color, music rhythm, music frequency band, volume, through real-time acquisition and analysis of electroencephalogram signals, to achieve personalized depression treatment. In addition, the present application greatly improves the accuracy of EEG signal acquisition through an innovative artifact elimination algorithm and electromagnetic shielding technology, and solves the problem that existing TMS and EEG combined devices are often subject to electromagnetic interference and artifact problems.

Provided are methods for treating depression and depression-related conditions by combining administration of pharmacologic agents and neuromodulation induced by transcranial electrical stimulation.

Methods, agents, and devices to treat medical conditions through local chemical neuromodulation of the autonomic nervous system are described. Drug formulations may be injected at or near ganglia, nerve plexi, ganglionated plexi, and nerves to treat different diseases. Target sites for the treatment of cardiac and other disease conditions may include extrinsic stellate (cervicothoracic) and cervical ganglia of the sympathetic chain, and intrinsic cardiac nerves and ganglionated plexi innervating the myocardium.