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2 results about "Poly-ADP-Ribosylation" patented technology
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The transfer of multiple ADP-ribose molecules to amino acids within target proteins.
Antisense oligonucleotides targeting downstream of the transcripts 3' terminus
PCT designated stageWO2026132147A1Organic active ingredientsDNA/RNA fragmentationPolyadenylationGenetics
The present invention describes that a pre-mRNA molecule, which temporarily exists before polyadenylation-site induced cleavage occurs, can be targeted by RNase H recruiting antisense oligonucleotides downstream of a transcripts 3' terminus to reduce expression levels of target genes from which the RNA polymerization originates.
Owner:F HOFFMANN LA ROCHE & CO AG +1
Targeted nuclear RNA splitting and polyadenylation with CRISPR-Cas
Owner:UNIVERSITY OF ROCHESTER