The invention, which belongs to the field of radiation detection technology, in particular relates to a low-temperature thermometer based on a scintillation crystal and temperature calibration and measurement methods thereof. The low-temperature thermometer is composed of a temperature measurement module, a power module, a signal collection and calculation module, and a data acquisition and display module. The temperature measurement module includes a lens hood, a photoelectric device and signal amplification module, a scintillation crystal, a radioactive Isotope source, a metal plate, a scintillation crystal, and a photoelectric device and signal amplification module, wherein the photoelectric device and signal amplification module, the scintillation crystal, the radioactive Isotope source, the metal plate, the scintillation crystal, and the photoelectric device and signal amplification module are arranged successively in the lens hood from bottom to top in a coaxial coupling manner.The power module is connected with the two photoelectric device and signal amplification modules respectively. The input terminal of the signal collection and calculation module is connected with theoutput terminal of the two photoelectric device and signal amplification modules respectively; and the output terminal of the signal collection and calculation module is connected with the data acquisition and display module. A novel solution is provided for temperature detection in the extremely-low-temperature environment in the universe.