The invention discloses a disinfecting and crushing apparatus for plastics medical waste. The disinfecting and crushing apparatus comprises a stander, wherein a cutting box, a transport cavity, an extruding box and a discharging cavity are arranged in the stander, the cutting box is disposed on the front end of the stander, the top end of the cutting box is provided with a feeding frame, the feeding frame is provided with a feeding hopper communicated with the cutting box, the bottom end of the cutting box is provided with a cutting motor, the top end of the cutting motor is provided with a cutting rotating shaft, the cutting rotating shaft stretches into the cutting box and is provided with a plurality of pairs of cutting blades and spiral rods, the cutting blades and the spiral rods aredistributed in an staggered manner, the bottom end of the cutting rotating shaft is provided with a brush rod, the outer end of the brush rod is provided with a cleaning brush, the bottom end of the cutting box is provided with a water outlet and a transport port, the cleaning brush is disposed right above the water outlet and the transport port, and the water outlet is connected with a water discharging pipe. The cleaning brush is driven by a brush rod to rotate, so that the material can be prevented from being adhered onto a bottom plate and influencing the output of materials, and the blockage condition of the material can be prevented.