The invention discloses a display panel and a pixel structure thereof. The display panel is formed by repeatedly stacking a plurality of display units. Each display unit is formed by arranging and combining a plurality of sub-pixels. The arrangement structure of the sub-pixels is of a 4*4 arrangement. According to the arrangement, a sub-pixel b, a sub-pixel d, a sub-pixel a and a sub-pixel d are sequentially arranged in the first line from left to right, a sub-pixel d, a sub-pixel c, a sub-pixel b and a sub-pixel c are sequentially arranged in the second line from left to right, a sub-pixel a, a sub-pixel b, a sub-pixel d and a sub-pixel b are sequentially arranged in the third line from left to right, a sub-pixel d, a sub-pixel c, a sub-pixel b and a sub-pixel a are sequentially arranged in the fourth line from left to right, and the sub-pixels a, the sub-pixels b, the sub-pixels c and the sub-pixels d are the sub-pixels different in colors.