412results about How to "Highly preventive effect" patented technology

A coating composition is disclosed which comprises an aqueous polymeric matrix, a hydrophilic polymer, a colloidal metal oxide and a crosslinker. The coating composition when applied on medical devices is hydrophilic, shows improved lubricity, abrasion resistance and substrate adhesion on metallic or plastic substrates. The coating also shows improved water sheeting thus providing the coated substrates with anti-fog properties. The coating absorbs aqueous dye or stain solutions making the substrate suitable for printing.

An improved type thin film semiconductor device and a method for forming the same are described. That is, in a thin film semiconductor device such as TFT formed on an insulating substrate, it is possible to prevent the intrusion of a mobile ion from a substrate or other parts, by forming the first blocking film comprising a silicon nitride, an aluminum oxide, an aluminum nitride, a tantalum oxide, and the like, under the semiconductor device through an insulating film used in a buffering, and then, by forming the second blocking film on TFT, and further, by covering TFT with the first and second blocking films.

Donepezil formulations, including amorphous donepezil or pharmaceutically acceptable salts thereof; sustained-release formulations; and donepezil sprinkle formulations are disclosed.

There is provided a method for making bituminous compositions comprising water-in-oil bituminous dispersion and aggregate by the steps of: preparing a solvent-free, water-in-oil bituminous dispersion comprising: (1) bitumen, in an amount from about 75.0% to about 95.0% by total weight of the bitumen dispersion; (2) a surfactant in an amount from about 0.05% to about 2.0% by total weight of the bitumen dispersion; and (3) water in an amount to complete the water-in-oil bituminous dispersion, and producing the bituminous composition having a temperature from about 50° C. to about 120° C. by mixing: (1) the water-in-oil bituminous dispersion of step (A), having a temperature from about 75° C. to about 95° C., in an amount from about 2.0% to about 10.0% by total weight of the bituminous composition, and (2) aggregate, having a temperature from about 60° C. to about 140° C., in an amount from about 90.0% to about 98.0% by total weight of the bituminous composition.

As a treatment for angiostenosis, angioplasty (PTA or PTCA) of expanding a small-sized balloon in a vessel has been commonly conducted. However, this treatment easily causes repeated stenosis (restenosis) after the treatment. Placement of a stent in a vessel is also effective in decreasing restenosis, but this treatment may also cause restenosis. The present invention provides a stent containing a poly (lactide-co-glycolide) or both a poly (lactide-co-glycolide) and an immunosuppressive agent in at least a portion of a surface of the stent, and further containing a material nondegradable in vivo.

Nucleic acid drug carriers comprise a nucleic acid carrier complexed with a drug, wherein the nucleic acid carrier and the drug are associated non-covalently, and optionally other agents such as spacer, transfection agents, and targeting agents. The nucleic acid drug complex are discovered to have permissive or refractory uptake depending on many factors including cell type, proliferation rate, among others. The refractive uptake of the nucleic acid drug complex are shown to be useful in the nucleic acid targeting of drugs, both in vitro and in vivo. Novel drug compositions are disclosed that effectively reduce the toxicity of drugs while maintaining drug activity and enhancing a drug's therapeutic index.

An automatic celestial navigation system for navigating both night and day by observation of K-band or H-band infrared light from multiple stars. In a first set of preferred embodiments three relatively large aperture telescopes are rigidly mounted on a movable platform such as a ship or airplane with each telescope being directed at a substantially different portion of sky. Embodiments in this first set tend to be relatively large and heavy, such as about one cubic meter and about 60 pounds. In a second set of preferred embodiments one or more smaller aperture telescopes are pivotably mounted on a movable platform such as a ship, airplane or missile so that the telescope or telescopes can be pivoted to point toward specific regions of the sky. Embodiments of this second set are mechanically more complicated than those of the first set, but are much smaller and lighter and are especially useful for guidance of aircraft and missiles. Telescope optics focus (on to a pixel array of a sensor) H-band or K-band light from one or more stars in the field of view of each telescope. Each system also includes an inclinometer, an accurate timing device and a computer processor having access to catalogued infrared star charts. The processor for each system is programmed with special algorithms to use image data from the infrared sensors, inclination information from the inclinometer, time information from the timing device and the catalogued star charts information to determine positions of the platform. Direction information from two stars is needed for locating the platform with respect to the celestial sphere. The computer is also preferably programmed to use this celestial position information to calculate latitude and longitude which may be displayed on a display device such as a monitor or used by a guidance control system. These embodiments are jam proof and insensitive to radio frequency interference. These systems provide efficient alternatives to GPS when GPS is unavailable and can be used for periodic augmentation of inertial navigation systems.

A method and device for connecting a bone conductor transducer contained in a housing to the skull bone for the transmission of vibrations characterized by, that the housing has at least one surface, which is placed against the bottom plane of a recess shaped in the temporal bone with a static force exceeding the dynamic signal forces.

The present invention relates to methods and compositions for treating neuropathic pain and neuropsychiatric disorders by administering agents that are effective in reducing the effective amount, inactivating, and/or inhibiting the activity of a Na⁺—K⁺-2Cl⁻ (NKCC) cotransporter. In certain embodiments, the Na⁺—K⁺-2Cl⁻ co-transporter is NKCC1.

According to the present invention, a circuit and methods for enhancing the operation of SOI fabricated devices are disclosed. In a preferred embodiment of the present invention, a pulse discharge circuit is provided. Here, a circuit is designed to provide a pulse that will discharge the accumulated electrical charge on the body of the SOI devices in the memory subarray just prior to the first access cycle. As explained above, once the accumulated charge has been dissipated, the speed penalty for successive accesses to the memory subarray is eliminated or greatly reduced. With a proper control signal, timing and sizing, this can be a very effective method to solve the problem associated with the SOI loading effect. Alternatively, instead of connecting the bodies of all SOI devices in a memory circuit to ground, the bodies of the N-channel FET pull-down devices of the local word line drivers can be selectively connected to a reference ground. This would enable the circuit to retain most of the speed advantages associated with SOI devices while overcoming the loading problem described above. With this preferred embodiment of the present invention, the major delay caused by the bipolar loading effect is minimized while the speed advantage due to providing a lower, variable Vt effect is preserved. The overall body resistance of the individual devices has a minimal effect on the device body potential.

The present invention provides a criterion for determining whether or not to apply de-duplication processing. That is, by setting a reduction effect threshold to control switching the de-duplication between ON and OFF, the present invention allows operation such that the de-duplication is applied for a volume for which a high capacity-reduction effect is provided by the de-duplication processing, and in contrast, the de-duplication is not applied to maintain performance for a volume for which a low capacity-reduction effect is provided by the de-duplication processing.

The present invention concerns an apparatus (1′) for NMR spectroscopy and/or NMR imaging of a sample. The apparatus comprises a static probe comprising an outer coil for excitation of nuclei of the sample by generating an incident radio frequency field at the Larmor frequency of the nuclei, and for reception of a return radio frequency field emitted by the sample, and a sensitive inner coil (6a′) which is mounted closely around or in contact with the sample container and which is wirelessly coupled to the outer coil by an electromagnetic radio frequency field. The sensitive inner coil is embedded in an inner spinning rotor (2) which is rotatively mounted inside the static probe and which is integral with the sample container, so that the filling factor and the radio frequency field amplitude in the sensitive coil are maximized.

Topically absorbable compositions with bioactive or bioavailable cannabis-derived cannabinoids known to be effective for CB1 or CB2 modulation, and a plurality of indications for patients in need, and methods for producing composition, without detectable or biologically active levels of THC. Method uses a heat cycle process to combine cannabinoids with flax seed oil and at least one triglyceride, to produce an extract. The extract can include non-psychoactive agents, namely, CBD and accordingly does not deleteriously impact federal legal schemes or bone fide drug-testing regimes.

A control device and a drug delivery system containing such a control device are disclosed for delivery to a patient of a drug or a placebo (or ineffective dose of the drug) according to a partial reinforcement schedule, whereby the placebo (or ineffective dose of the drug) is delivered in whole or in part during one or more delivery events. Methods of modulating the drug/placebo delivery to a patient are also provided, whereby the delivery event is initiated either according to a patient-initiated signaling event (i.e., a self-medication mode) or an automated signaling event (i.e., automated mode).

Inversion carbon blacks and a method for their manufacture are disclosed. The inversion carbon blacks have a lower rolling resistance with identical or improved wet skid behavior. The particle size distribution contains a smaller proportion of particles with large diameters. This leads to an improved abrasion behavior of rubber compounds which were prepared using these carbon blacks. The inversion carbon blacks can be manufactured in conventional carbon black reactors by controlling the combustion in the combustion chamber in such a manner that carbon black nuclei form, which are immediately brought into contact with the carbon black raw material. The carbon blacks present a lower proportion of larger particles if the additions of combustion air and carbon black raw material are increased in an appropriate manner.

A protective undergarment (10), shown in the form of shorts, includes integrally formed protective panels (22, 26, 30) that exhibit slash-proof properties. The protective areas (22, 26, 30) are made from a flexible Kevlar® knit or the like, and extend to cover the groin, crotch, substantial areas of the buttocks and the inner thigh regions of both legs. The protective panels (22, 26, 30) are externally snitched to a low thermal burden material (18, 20), such as a polyester mesh, that provides elasticity and completes the structure of the shorts (10). The Kevlar® knit is flexible and preferably lies directly against the skin of a user to provide blast wave and ballistic fragment deflection whilst permitting mobility in a lightweight arrangement. Varying thickness of the Kevlar® knit can be used in the protective areas (22, 26, 30) selectively to enhance protection against blast wave and fragment penetration. The shorts (10) find particular application in battlefield theatres where military personnel are exposed to bomb threats.

A test circuit adapted in a display panel of an electronic device is provided. The test circuit is to test the pixel array function of the display panel, wherein the test circuit comprises: a plurality of test signal lines, a plurality of test signal transmitters, a plurality of gate lines and at least one static electricity protection device. The test signal lines receive a plurality of corresponding test signals respectively. The test signal transmitters comprises a plurality test signal transmitter groups comprising at least one transmitter, wherein each transmitter group corresponds to a test signal line and connects the test signal line and the pixel array. Each gate line connects to the gate of the at least one transmitter. The static electricity protection device is placed between two of the gate lines.