The invention discloses a foundation vibration isolation and three-dimensional damping structure for a double-layer containment nuclear power station. The foundation vibration isolation and three-dimensional damping structure comprises an inner containment, an outer containment, a reactor core supporting structure, a reactor core structure, a horizontal vibration isolation supporting seat, a vertical vibration isolation supporting seat, a vertical damper, a bidirectional hydraulic cylinder and a damping sliding block, the damping sliding block and the outer containment are in vertical slidingdamping fit, the end of a first piston rod of the bidirectional hydraulic cylinder is connected with the inner containment, a second piston rod of the bidirectional hydraulic cylinder is connected with the damping sliding block, when the first piston rod moves horizontally, the second piston rod drives the damping sliding block to slide in the vertical direction relative to the outer containment.According to the foundation vibration isolation and three-dimensional damping structure for the double-layer containment nuclear power station, through the combined action of the horizontal vibrationisolation supporting seat, the bidirectional hydraulic cylinder, the damping sliding block, the vertical vibration isolation supporting seat and the vertical damper which are arranged, the three-dimensional damping effect is achieved, the special anti-seismic safety requirement of the nuclear power station can be met, and the anti-seismic safety of the nuclear power station structure is remarkablyimproved.