The invention relates to a treatment and regenerative cyclic utilization device for tobacco sheet production wastewater. The treatment and regenerative cyclic utilization device comprises a mechanical coarse-grille water collecting basin, a rotary fine-grille machine, a regulation pool, a primary decalcification reaction pool, a secondary decalcification reaction pool, a primary sedimentation tank, a filtering device, a coagulation tank, an air flotation tank, a UASB (Upflow Anaerobic Sludge Blanket) anaerobic tank, an electrolyzer a, an anaerobic pool, an aerobic pool, a secondary sedimentation tank, an electrolyzer b, a membrane treatment device or biological aerated filter, an electrolyzer c, a water supply pump, a desalting device, a reclaimed water storage tank, a sludge tank, a sludge dewatering device, an accident pool, a gas collection device and a marsh gas storage tank. The treatment and regenerative cyclic utilization device has the advantages that on the basis that chemical decalcification techniques, biochemical techniques, electrochemical techniques, BAF (Biological Aerated Filter) techniques and membrane technologies are combined, the cost is lower, and the efficiency is higher; after the tobacco sheet production wastewater is treated, 75-85% of the tobacco sheet production wastewater can be utilized in a regenerative and cyclic manner, so that the discharge of the wastewater is reduced, the environmental pollution caused by the wastewater is avoided, and the waste of water resources is reduced; and the cost of reclaimed recycled water can be lower than the price of tap water, so that the reclaimed recycled water is economical and reasonable, and a better economic benefit is generated.