A mechanical transmission device is capable of enhancing the cutting property of a ball-end milling cutter, and comprises a driving shaft, an intermediate shaft, a plurality of gears (cylindrical gear, internal gear, bevel gear, spiral gear), a driven shaft and a milling cutter; the driving shaft and the driven shaft form an included angle; when a main shaft is driven to rotate by a power source, the main shaft drives the driven shaft to rotate around the main shaft by the gears and rotates around the axis. The centre of the ball-end is corrected by a scale or by other methods, so as to be arranged on the centre line of the main shaft. The method is simple and convenient. Therefore, the centre part of the ball-end milling cutter does not participate in cutting due to the fact that the centre part is likely to tip and wear. The part of the end face of the ball-end milling cutter which does not participate in cutting is increased along with the increment of included angle between the driving shaft and the driven shaft. The centre of the ball-end milling cutter is avoided from tipping, thereby enhancing the wearing resistance of the cutter, fastening the cutter feeding speed, and improving the cutting efficiency.