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The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGPs), methods of manufacture, and their use to facilitate administration of other molecules or to alleviate glycosaminoglycan associated pathologies. Minimally active polypeptide domains of the soluble, neutral active sHASEGP domains are described that include asparagine-linked sugar moieties required for a functional neutral active hyaluronidase domain. Included are modified amino-terminal leader peptides that enhance secretion of sHASEGP. The invention further comprises sialated and pegylated forms of a recombinant sHASEGP to enhance stability and serum pharmacokinetics over naturally occurring slaughterhouse enzymes. Further described are suitable formulations of a substantially purified recombinant sHASEGP glycoprotein derived from a eukaryotic cell that generate the proper glycosylation required for its optimal activity.

A lighting device includes a base, a heat-conducting element, a heat-conducting column and two light-emitting components. The base includes a first surface and a second surface opposite to each other. The heat-conducting element is disposed on the first surface of the base. One end of the heat-conducting column is disposed on the second surface of the base and connected to heat-conducting element, and the heat-conducting column includes a first edge. The light-emitting components are disposed on two adjacent surfaces of said heat-conducting column separated by said first edge. The light-emitting components include two substrates and two light-emitting units. The substrates are disposed on two opposite sides of said first edge of said heat-conducting column, and each of the substrates includes a sidewall adjacent to the first edge. The light-emitting units are disposed on the substrates, and an outer edge of the light-emitting unit is adjacent to the corresponding sidewall.

A switch circuit for switching the connection of the receiving or transmitting circuits of two communication systems to an antenna circuit, which comprises first and second switch means having two switching elements, the first switch means comprising a first inductance element between a port connected to the antenna circuit and a port connected to the second switch means; the second switch means comprising a second inductance element between a port connected to the first switch means and a port connected to a receiving circuit of a first communication system, and a transmission line constituting the first inductance element having a lower characteristic impedance than that of a transmission line constituting the second inductance element.

A conductor includes a first flow path portion and a second flow path portion through which a current as a measurement target flows in a branched manner at a halfway position in a lengthwise direction of the conductor. The first flow path portion and the second flow path portion are located with a space therebetween in the width direction of the conductor when viewed from the thickness direction of the conductor. A region surrounded by the first flow path portion and the second flow path portion is provided when viewed from the width direction of the conductor. At least a portion of a substrate is located in the region and opposes at least one of the first flow path portion and the second flow path portion when viewed from the width direction of the conductor. The first magnetic sensor and the second magnetic sensor are arranged in the space.

The present invention relates to organic conductive polymer compositions adapted to produce touch panel input devices that hardly undergo resistance degradation even after prolonged and repeated usages, and represent remarkably improved reliability and lifetime in particular. The organic conductive polymer compositions according to the present invention comprise a thiophene derivative polymer, a water-soluble organic compound (except for nitrogen-containing compounds), and a dopant, wherein the thiophene derivative polymer is expressed by the formula (1)

A manufacturing method of substrate structure is provided. A base material having a core layer, a first patterned copper layer, a second patterned copper layer and at least one conductive via is provided. The first and second patterned copper layers are respectively located on a first surface and a second surface of the core layer. The conductive via passes through the core layer and connects the first and second patterned copper layers. A first and a second solder mask layers are respectively formed on the first and second surfaces. Portions of the first and second patterned copper layers are exposed by the first and second solder mask layers, respectively. A first gold layer is formed on the first and second patterned copper layers exposed by the first and second solder mask layers. A nickel layer and a second gold layer are successively formed on the first gold layer.

An image sensing apparatus and a black level controlling method thereof are provided. The black level controlling method includes following steps. A conversion relationship between analog gain values and offset values is provided. An analog gain value is converted into an analog offset value by using the conversion relationship between analog gain values and offset values. Whether to adjust the analog offset value is decided according to a first optical black data corresponding to a first part of optical black pixels. A digital data offset value is calculated according to a data corresponding a second part of optical black pixels.

The present invention relates to organic conductive polymer compositions adapted to produce touch panel input devices that hardly undergo resistance degradation even after prolonged and repeated usages, and represent remarkably improved reliability and lifetime in particular. The organic conductive polymer compositions according to the present invention comprise a thiophene derivative polymer, a water-soluble organic compound (except for nitrogen-containing compounds), and a dopant, wherein the thiophene derivative polymer is expressed by the formula (1).