The invention discloses a vacuum
gate valve for a
mass spectrometer. The vacuum
gate valve comprises a
valve seat and a valve element, and a sealing ring is arranged between the
valve seat and the valve element. The valve element is provided with a squeezing mechanism used for enabling the valve element to tightly press the sealing ring. The invention further discloses a
mass spectrometry instrument, the
mass spectrometry instrument comprises an
ion source cavity and an analysis chamber which is communicated with the
ion source cavity, and a communicated channel of the
ion source cavity and the analysis chamber is provided with the vacuum
gate valve. In addition, the invention discloses a method for establishing a high vacuum environment in
mass spectrometry sample change. The method includes the steps that the communicated channel of the
ion source cavity and the analysis chamber is closed through the vacuum gate valve, the
ion source cavity is opened for changing samples, after the samples are changed, the
ion source cavity is pre-vacuumized, the vacuum gate valve is opened so that the ion source cavity and the analysis chamfer can be communicated with each other, and vacuumizing is conducted. According to the devices and the method, the vacuum needed by detection of the mass
spectrometer can be established quickly after the samples are changed, the sealing effect is good, and the sample changing efficiency is high.