The invention discloses a
pathology grading method and
system based on HER2 immunohistochemical pictures, belongs to the technical field of immunohistochemical (IHC),
bioinformatics and
medical diagnosis, is used for carrying out
pathology grading on a
test sample, and comprises the following steps: collecting and
processing a plurality of original HER2 immunohistochemical pictures of the
test sample, and obtaining a sample picture set for
pathology grading; reading a sample picture set and converting an
RGB color space in the sample picture set into an HSV
color space; determining the
staining intensity and range of the
cell membrane based on the immunohistochemical picture in the sample picture set converted to the HSV
color space; extracting and determining the membrane rate based on the characterization of the
dyeing intensity and range of the
cell membrane, and carrying out test treatment on the membrane rate to obtain the membrane rate of the
test set; the film rate is the ratio of the pixel where the film is located to the background pixel; evaluating the
test sample based on the corrected membrane rate data, and performing
pathological grading on HER2 expression in the test sample based on a grading
system. The invention further discloses a
system,
electronic equipment and a computer readable storage medium.