The invention relates to the technical field of fundus detection, in particular to a fundus three-dimensional
topography measurement
system and method based on
human eye dynamic response coding, which can realize novel fundus three-dimensional
topography measurement which does not depend on a precise mechanical structure, does not need binocular registration, and is simple to assemble and operate, simple in
system and controllable in cost. The dynamic adjustment capability of a crystalline lens of a
human eye is used as an imaging driving mechanism, the
human eye is guided to continuously adjust the
focal length by projecting a dynamic
virtual image with far and near changes, a focus stack is generated through coding for three-dimensional reconstruction, finally, a fundus color picture and three-dimensional structure data of the fundus color picture are synchronously obtained, and accurate measurement of the fundus three-dimensional shape is achieved. The method does not need complex registration operation of
binocular stereo imaging and
image texture dependence during three-dimensional reconstruction, and also does not need complex scanning mechanisms and precision machines of
laser scanning
ophthalmoscopes,
optical coherence tomography and other technologies, so that the
system hardware cost and the operation difficulty are reduced, and the method is easier to popularize and apply in basic medical scenes.