The invention relates to the technical field of fixed-wing aircrafts, in particular to a fixed-wing aircraft control system and method based on 5G communication, the fixed-wing aircraft control systemcomprises a fixed-wing aircraft, 5G CPE equipment, a server and a ground receiving terminal, and the fixed-wing aircraft is provided with an air pressure and temperature and humidity sensor, a GPS positioner, an airspeed meter and a data integration module; a flight controller, a return controller and a touch display are installed on the ground receiving terminal, the 5G CPE equipment is fixed onthe fixed-wing aircraft, the server is close to the ground receiving terminal, and output end electrodes on an air pressure sensor, a temperature and humidity sensor, a GPS positioner and an airspeedmeter on the fixed-wing aircraft are connected with the input end of a data integration module. The automatic homeward voyage protection system is arranged, the fixed-wing aircraft is prevented fromlosing communication, 5G CPE equipment is installed on the fixed-wing aircraft, network delay is avoided, control smoothness is facilitated, and signal interference is reduced.