The invention provides a low-
dose CT image self-supervision denoising method based on axial structure consistency, and belongs to the technical field of medical
image processing and
deep learning. The method comprises the following steps of: inputting a
DICOM (
Digital Imaging and Communications in
Medicine)
image sequence scanned by original LDCT (Level
Discrete Cosine Transform), extracting three continuous axial slices to generate a triple sample
data set, and calculating an axial difference image of two adjacent slices to construct a two-tuple
data set; the method comprises the following steps: after constructing a double-
branch neural network framework of a denoising network and a difference enhancement network, respectively outputting a denoised triple and axial structure offset
estimation, and calculating a pseudo-supervision
signal; and on the basis of the pseudo-supervised
signal and the denoised triple, calculating by constructing a self-supervised joint loss optimization function to obtain a model for denoising the low-
dose CT image. According to the method, the problems of axial structure
dislocation, high-frequency detail loss, excessive smoothness and the like in an existing self-supervised denoising method are effectively solved, and the
structural consistency and detail fidelity of the image are remarkably improved while
noise suppression is ensured.