41results about How to "Improve the ability to resist external pathogen infection" patented technology

Provided is a milk-derived biologically active polypeptide having an amino acid sequence of QEPV, which has in-vitro antioxidation activity and enhances immunity of human body. The polypeptide has good biological antioxidation activity, and has the function of enhancing immunity of cells and human body.

The present invention proposes a kind of ointment that can improve leukocyte content, and is prepared from the following raw materials by weight: 10-20 parts of carboxymethyl polysaccharide, 12-17 parts of colostrum basic protein, and 5-parts of wheat oligopeptide 10 parts, 35‑40 parts of mulberry, 5‑10 parts of longan meat, 10‑20 parts of coix seed, 20‑25 parts of sealwort, 10‑20 parts of yam, 20‑25 parts of jujube and 15‑20 parts of honey. The ointment of the invention has the effects of enhancing the body's immunity, increasing the leukocyte content in the blood, improving the body's ability to withstand hypoxia, and the like. It has definite curative effect on the treatment of diseases such as low immune function and leukopenia. The invention has wide sources of raw materials, simple preparation method, and the prepared ointment has a good effect of improving immunity, can increase the content of white blood cells, stimulate the proliferation of lymphocytes, reduce the incidence of body diseases, and has broad application prospects.

The present invention relates to the field of proteins, in particular to a bioactive peptide KQSLPPGLAVKDLK and its preparation method and application. The amino acid sequence of the bioactive peptide KQSLPPGLAVKDLK is Lys‑Gln‑Ser‑Leu‑Pro‑Pro‑Pro‑Gly‑Leu‑Ala‑Val‑Lys ‑Asp‑Leu‑Lys. The in vitro immune function regulation experiment proved that the biologically active peptide KQSLPPGLAVKDLK has a good immune regulation function. The biologically active peptide KQSLPPGLAVKDLK of the present invention has the ability to enhance the in vitro proliferation of macrophages and lymphocytes, improve the ability of the body to resist external pathogen infection, reduce the incidence of the body, improve the quality of life, and is useful for the development of food and health products with immune regulation functions. and drugs are of great importance.

Provided is a milk-derived biologically active polypeptide having an amino acid sequence of DELQ, which has in-vitro antioxidation activity and promotes immune activity of human body. In-vitro antioxidation and in-vitro immunity promotion experiments prove that the peptide has good biological antioxidation activity, and has the function of enhancing cellular immunity.

Provided is a polypeptide, the amino acid sequence of which is SLPQ. The polypeptide is prepared by fermented skimmed milk by Lactobacillus helveticus. The polypeptide can enhance immunity of a body, so also provided are food, health products and medicines comprising the polypeptide.

The invention relates to the field of proteins, in particular to a biologically active peptide RLAFIAHPKLG and a preparation method and application thereof. The amino acid sequence of the biologically active peptide RAFIAHPKLG is Arg-Leu-Ala-Phe-Ile-Ala-His-Pro-Lys-Leu-Gly . Through in vitro immunomodulatory function experiments, it was found that the biologically active peptide RLAFIAHPKLG has a good immunomodulatory function. The bioactive peptide RLAFIAHPKLG of the present invention has the ability to enhance the in vitro proliferation ability of lymphocytes, can promote macrophages to secrete cytokines, improve the body's ability to resist infection by external pathogens, reduce the body morbidity rate, improve the quality of life, and has immunomodulatory effects on development Functional foods, health products and medicines are of great significance.

The present invention relates to the field of proteins, in particular to a bioactive peptide LECVEPNCRSKR and its preparation method and application. The amino acid sequence of the bioactive peptide LECVEPNCRSKR is Leu-Glu-Cys-Val-Glu-Pro-Asn-Cys-Arg-Ser-Lys ‑Arg. Through the in vitro immune function regulation experiments, it was verified that the biologically active peptide LECVEPNCRSKR has a good immune regulation function. The biologically active peptide LECVEPNCRSKR of the present invention has the ability to increase the induction of macrophage nitric oxide under a certain concentration, can effectively inhibit the inflammation caused by oxidation in the body, inhibit the overexpression of inflammatory factors, and improve the body's resistance to external pathogens The ability to infect, reduce the morbidity of the body, and improve the quality of life are of great significance to the development of foods, health products and medicines with immune regulation functions.

Provided is a milk-derived biologically active polypeptide having an amino acid sequence of LPLP, which has in-vitro antioxidation activity and enhances immunity of human body. The polypeptide has good biological antioxidation activity, and has the function of enhancing immunity of cells and human body.

The invention provides a nutritious food with a function of boosting immunity and a preparation method of the nutritious food. The nutritious food disclosed by the invention comprises the following components in percentage by weight: 5%-10% of wheat oligopeptides powder, 0.08%-0.12% of zinc gluconate, 0.03%-0.05% of vitamin B2, 12%-16% of lentinus edodes powder, 10%-14% of whole milk powder, 8%-12% of isolated soy protein powder, 7%-11% of oat powder, and 40%-60% of an auxiliary material. The nutritious food provided by the invention is reasonable in component matching, is capable of providing various nutritional ingredients such as sufficient protein, amino acids, mineral substances, vitamins for a human body, simultaneously has the efficacies of improving the immunity of the organisms and reducing the disease risk of the human body, is especially suitable for being used as a breakfast assist or substitute food; and in addition, the nutritious food disclosed by the invention is good in taste and flavor, convenient to eat, easy to absorb by the human body, and wide in market prospect, and meets the consumption needs of modern society people.

The present invention relates to the field of proteins, in particular to a bioactive peptide GGYGSGGGSGGYGSRRF and its preparation method and application. The amino acid sequence of the bioactive peptide GGYGSGGGSGGYGSRRF is Gly-Gly-Tyr-Gly-Ser-Gly-Gly-Gly-Ser-Gly-Gly ‑Tyr‑Gly‑Ser‑Arg‑Arg‑Phe. After the verification experiment of immune regulation function in vitro, it was found that the biologically active peptide GGYGSGGGSGGYGSRRF has a good immune regulation function. The biologically active peptide GGYGSGGGSGGYGSRRF of the present invention can significantly enhance the in vitro proliferation ability of macrophages, can effectively inhibit inflammation caused by oxidation, has a good immune regulation effect, can improve the body's ability to resist external pathogen infection, and reduce the body's morbidity , improving the quality of life is of great significance to the development of food, health products and medicines with immune regulation function.

The present invention relates to the field of proteins, in particular to a bioactive peptide ASEPPVLDVKRPFLC and its preparation method and application. The amino acid sequence of the bioactive peptide ASEPPVLDVKRPFLC is Ala‑Ser‑Glu‑Pro‑Pro‑Val‑Leu‑Asp‑Val‑Lys‑Arg ‑Pro‑Phe‑Leu‑Cys. The in vitro immune function regulation experiment verified that the biologically active peptide ASEPPVLDVKRPFLC has a good immune regulation function. The biologically active peptide ASEPPVLDVKRPFLC of the present invention can effectively inhibit the inflammation caused by oxidation in the body, promote the secretion of cytokines by macrophages, improve its function in the resting state of normal macrophages, improve the body's ability to resist external pathogen infection, reduce It is of great significance to develop food, health care products and medicines with immune regulation function to reduce the incidence of the body and improve the quality of life.

The present invention relates to the field of protein, in particular to a biologically active peptide having an amino acid structure VVRKPLNKEGKKP and its preparation method and application. The amino acid sequence of the biologically active peptide VVRKPLNKEGKKP is shown in SEQ ID NO: 1, and the amino acid sequence of the biologically active peptide VVRKPLNKEGKKPR is shown in SEQ ID NO: 2 shown. In vitro immunoregulatory function experiments have proved that the bioactive peptides VVRKPLNKEGKKP and VVRKPLNKEGKKPR have good immune regulatory functions. The VVRKPLNKEGKKP and VVRKPLNKEGKKPR of the present invention have the ability to promote the increase in the induction of macrophage nitric oxide under certain concentration conditions, thereby improving the body's ability to resist external pathogen infection, reducing the incidence of the body, and at the same time promoting the proliferation of macrophages in vitro and exerting their full potential. The immune function of the body is of great significance to the development of food, health products and medicines with immune regulation function.

The present invention relates to the field of proteins, in particular to a bioactive peptide IAHPKLGKRIR and its preparation method and application. The amino acid sequence of the bioactive peptide IAHPKLGKRIR is Ile‑Ala‑His‑Pro‑Lys‑Leu‑Gly‑Lys‑Arg‑Ile‑Arg . In vitro immune function regulation experiments proved that the biologically active peptide IAHPKLGKRIR has a good immune regulation function. The biologically active peptide IAHPKLGKRIR of the present invention can promote the proliferation ability of lymphocytes in vitro, improve the immunity of the human body, and at the same time have a significant promotion effect on the ability of macrophages to phagocytize neutral red in vitro, improve the body's ability to resist external pathogen infection, reduce the body's It is of great significance to develop food, health care products and medicines with immune regulation function and improve the quality of life.