37results about How to "Lower serum triglycerides" patented technology

The invention relates to a method for processing instant coarse cereal balanced nutritional flour, which comprises the following steps of: (1) mixing 25 to 30 percent of buckwheat flour, 10 to 15 percent of fagopyrum tataricum flour, 8 to 12 percent of hulless oat flour, 15 to 20 percent of hyacinth bean flour and 30 to 35 percent of pea flour to obtain mixed flour; (2) adding water into the mixed flour and blending to form flour paste, adding solution of CaCl2 to ensure that the pH value of the flour paste is between 6.0 and 6.5, adding 140 to 160u of intermediate-temperature alpha-amylase into each gram of mixed flour, and liquefying at the temperature of between 60 and 65 DEG C to obtain liquefied flour milk; and (3) decoloring the liquefied flour milk, seasoning, and spray-drying to obtain a finished product. The method is simple, easy to operate and master, low in production cost and environment-friendly, the obtained product has high instant and blending performance, is convenient to eat, has an adjuvant therapy effect on senile diseases such as hypertension, hyperlipaemia, cardiovascular and cerebrovascular diseases, diabetes, obesity and the like, and has better effects of dietetic therapy and health care than rice and wheat flour.

The present disclosure relates to compounds of the general formula (I):whereinR1 and R2 are the same or different and are chosen from a hydrogen atom, a hydroxy group, an alkyl group, a halogen atom, an alkoxy group, an acyloxy group, an acyl group, an alkenyl group, an alkynyl group, an aryl group, an alkylthio group, an alkoxycarbonyl group, an alkylsulfinyl group, an alkylsulfonyl group, an amino group, and an alkylamino group;or any pharmaceutically acceptable salt, solvate, complex, or pro-drug thereof;and their use as medicaments for the treatment of various diseases and conditions, for example, reduction of elevated triglyceride levels, i.e., hypertriglyceridemia, reduction of non-HDL cholesterol, reduction of glucose and HbA1c, and improvement of insulin resistance. The present disclosure also relates to a pharmaceutical composition comprising compounds of formula (I), as well as to processes for preparing compounds according to formula (I).

The night taken Tibetan medicine for treating diabetes is prepared with bear bile, emblic, saffron, artificial musk, amur barberry bark and other four kinds of medicinal materials, and through grinding into fine powder and mixing in certain weight proportion. It may be prepared into bolus, medicine powder, soft capsule or granule. The Tibetan medicine can lower blood sugar and lower serum triglyceride, and has also obvious curative effect on nephrosis. It has fast absorption of the effective components in the medicine and high curative effect.

The invention relates to a healthcare tea electuary for treating constipation and belongs to the field of nutritious foods. The healthcare tea electuary is made by linseed hull fiber, ginseng leaf, mulberry, fructus ligustri lucidi, snake gourd seed and the like. The healthcare tea electuary is capable of performing the therapeutic principle of traditional Chinese medicine, increasing immunity, nourishing yin, clearing heat and relaxing bowels, and good in effect, and fast to take effect.

A medical composition for losing weight and preventing and treating the diseases associated with obesity is prepared from berberine and oryzanol in weight ratio of (8-8.5):1.

The invention is about the recombination plasmid containing the PON gene and its application. The recombination plasmid, the cell and the compound can prevent and cure the toxic of the organophosphor, hyperlipemia, atherosclerosis, glycuresis.

The invention provides lotus leaf dark tea and a producing method thereof. The dark tea mainly comprises the following components in parts by weight: 5-15 parts of a lotus leaf extract, and 85-95 parts of dark tea. The two components are matched according to a specific proportion and mutually cooperated, the lotus leaf dark tea component has effects for adjusting body metabolism, accelerating lipid metabolism, enhancing stomach function, and promoting digestion, and long term drinking of the product has good fat-reducing efficacy. The lotus leaf extract is added into the fermented dark tea, so that in the respect of mouthfeel, the product has heavy and thick, and mellow tastes of the dark tea, and light delicate fragrance of lotus leaves.

The invention relates to a drug for treating hyperlipidemia and a preparation method thereof. The drug is prepared by the following pharmaceutical raw materials: ginkgo leaf, hawthorn leaf, cassia seed, turmeric root-tuber, Mongolian snakegourd root, danshen root, sanchi, oriental waterplantain rhizome and prepared tuber fleeceflower root. The preparation steps thereof are as follows: 1) the sanchi is taken and smashed into fine powder, the ginkgo leaf and the hawthorn leaf are additionally taken and smashed into coarse powder, the percolation is carried out, percolate is collected, the recovery of ethanol with the reduced pressure is carried out, then the dilution, the removal of pigments and the separation of a water layer are carried out, ethyl acetate is used for shaking extraction, and the ethyl acetate is recovered with the reduced pressure from extract liquid and concentrated till the ethyl acetate is dry; 2) the cassia seed, the turmeric root-tuber, the Mongolian snakegourd root, the danshen root, the oriental waterplantain rhizome and the prepared tuber fleeceflower root are taken, 80 percent ethanol is used for reflux for two times, filtrate is merged, and the ethanol is recovered and vacuum-concentrated to a clear paste with the relative density of 1.40 and the temperature of 50 DEG C; and 3) the various medicine residues after the ethanol extraction are merged, then water is added for carrying out three times of decoction, decocted liquid is merged and filtered, then the standing is carried out, supernatant fluid is taken and concentrated to a thick paste, an extract of the step 2 and the sanchi powder are further added for even mixing, the mixture is dried at the temperature of 60 DEG C and then ground to the fine powder with 100 meshes, and the packaging into capsules with 0.5g is finally carried out for preparation.

The present invention provides a chinese medicinal composition for curing hyperlipemia, cerebral arteriosclerosis and ischemic apoplexy and method of preparing the same. The chinese medicinal composition is composed of components as follows: ginseng 150-800 weight parts, prepared fleece-flower root 2300-9200weight parts, safflower 650-2600weight parts, hawkthorn 1350-5400 weight parts, epimedium 1350-5400 weight parts, ginseng leaves 1000-4000 weight parts, grassleaved sweetflag 650-2600 weight parts, notoginseng 330-1320 weight parts, chuanxiong rhizome 750-3000 weight parts, salvia root 2000-8000 weight parts, mistletoe 1350-5400 weight parts, root of kudzu vine 1800-7200 weight parts, buffalo horn 4000-16000 weight parts, borneol 10-40 weight parts. Composition of the present invention is to supplement qi and activate blood circulation, disperse blood stasis and dredge collateral, regain consciousness, tranquilization and intelligence development, auxiliary nourishing the liver and kidney, regulating the spleen and stomach; complementing without dryness, running without losing, soft and moist with profit, without harm of cool, warm and dry, approaching objective of curing both deficiency and excess.

The morning taken Tibetan medicine for treating diabetes is prepared with 18 kinds of Chinese medicinal materials, including bear bile, saffron, artificial musk, amur barbery bark, etc. The preparation process includes grinding all the medicine materials into fine powder, mixing in certain weight proportion and other steps. It is prepared into medicine powder, and may be also prepared into bolus, capsule, soft capsule or granule. It can reduce blood sugar and reduce serum triglyceride and has also obvious curative effect on nephrosis.

The invention discloses a production method of red-yeast glutinous rice wine. The production method comprises the following production steps of (1), weighing and taking glutinous rice, cleanly washingby using clear water, and soaking for 1 to 3 hours by using clear water; (2), well streaming the glutinous rice, so as to obtain steamed glutinous rice; (3), cooling the well steamed glutinous rice to 35 to 38 DEG C; (4), taking sweet wine yeast, and melting by using warm boiled water at 38 DEG C or less for later use; (5), crosswise mixing red yeast with the cooled steamed glutinous rice together, wherein the weight ratio of the red yeast to the glutinous rice is (1 to 4) to 10; (6), pouring the well mixed red yeast and the steamed glutinous rice into a vat, sprinkling by using the melted sweet wine yeast, afterwards, sealing, fermenting for 12 to 24 hours, then adding rice wine brewed by a pure grain, putting the vat at a shady, cool and dry place, standing, sealing and fermenting for 60 to 200 days; (7), filtering fermented matters in the vat, taking liquid, passing inspection, bottling and sealing, so that a product can be obtained. The red-yeast glutinous rice wine is simple in production process and low in production cost, and has the functions of strengthening the spleen, eliminating stomach dryness, activating blood circulation to dissipate blood stasis, warming uterus fordispelling cold, maintaining beauty and keeping young.

The invention discloses a traditional Chinese medicinal composition for reducing blood lipid, which is prepared from the following raw materials in parts by weight: 15-20 parts of Panax notoginseng, 30-35 parts of Salvia miltiorrhiza, 30-35 parts of Ginkgo biloba leaf, 15-20 parts of Semen Cassiae, 25-30 parts of Radix Puerariae, 15-20 parts of Silybum marianum, 15-20 parts of Astragalus membranaceus,5-10 parts of Benincasa hispida peel, 10-15 parts of Bletilla striata, 2-6 parts of Solanum surattense, 10-15 parts of Radix Glycyrrhizae, and 5-10 parts of Herba Artemisiae Scopariae. The preparation method includes reflux-extracting with ethanol, drying, granulating and encapsulating. The traditional Chinese medicinal composition disclosed by the invention uses pure natural Chinese medicinal herbs to achieve blood lipid reducing and regulating effects by synergistic action.

The invention provides a traditional Chinese medicine compound for treating hyperlipidaemia, cerebral arteriosclerosis and ischemic stroke and a preparation method thereof. The traditional Chinese medicine compound provided by the invention comprises the following components in parts by weight: 150-600 parts of ginseng, 2300-9200 parts of prepared polygonum multiflorum, 650-2600 parts of safflower, 1350-5400 parts of hawthorn, 1350-5400 parts of epimedium herb, 1000-4000 parts of ginseng leaf, 650-2600 parts of rhizoma acori graminei, 330-1320 parts of pseudo-ginseng, 750-3000 parts of ligusticum wallichii, 2000-8000 parts of the root of red-rooted salvia, 1350-5400 parts of parasitic loranthus, 1800-7200 parts of the root of kudzu vine, 4000-16000 parts of cornu bubali and 10-40 parts of borneol. The formula of the traditional Chinese medicine compound provided by the invention has the efficacies of tonifying qi, invigorating blood circulation, eliminating blood stasis, activating collaterals, refreshing brain, restoring consciousness, calming nerves, developing intelligence, nourishing liver and kidneys and regulating spleen and stomach; the whole body is nourished and does not generate dryness; the collaterals are smooth but not loose; the whole body have smoothness in softness and moistness; the defects of coldness and dryness-heat do not exist; and the purposes of virtually and actually treating both the symptoms and root causes are reached.

The invention provides application of compounds or pharmaceutically acceptable salts shown as the general formula I, and application of pharmaceutical compositions and plant extract products both containing the compounds or the pharmaceutically acceptable salts. The compounds or pharmaceutically acceptable salts of the general formula I, the pharmaceutical compositions and the plant extract products are capable of increasing the transcription of lipoprotein lipase in adipocyte in cell level, thereby improving lipid metabolism. Therefore, the compounds or pharmaceutically acceptable salts of the general formula I, the pharmaceutical compositions and the plant extract products are applicable to prepare medicines for treating II type diabetes and hypertriglyceridemia.

The invention relates to a preparation method of red yeast rice and glutinous rice wine with blood circulation activating and kidney tonifying effects. The preparation method comprises the following steps of (1) respectively weighing black glutinous rice and white glutinous rice, cleaning by clean water, and soaking by clean water for 1 to 3h; (2) respectively steaming the black glutinous rice andthe white glutinous rice, so as to obtain steamed glutinous rice; (3) airing the steamed glutinous rice to the temperature of 35 to 38 DEG C; (4) weighing sweat distiller's yeast, and dissolving by warm boiled water for further use; (5) mixing and stirring the red yeast rice and the aired glutinous rice according to a weight ratio of (1 to 4):10; (6) pouring the mixed red yeast rice and steamed glutinous rice into a jar, spraying the dissolved sweat distiller's yeast, sealing and fermenting for 12 to 24h, adding pure grain-brewed rice wine, placing the jar in a shady dry area, standing, and sealing and fermenting for 60 to 200 days; (7) filtering fermenting matter in the jar, obtaining filtrate, and bottling and sealing after the filtrate is qualified in inspection, so as to obtain the product. The preparation method of the red yeast rice and glutinous rice wine has the advantages that the preparation technology is simple, the preparation cost is low, and the effects of activating blood circulation and removing blood stasis as well as tonifying spleen and invigorating Qi are realized.

The invention discloses a Chinese medicinal composition for preventing and treating hyperlipaemia and fatty liver and a preparation method thereof. The Chinese medicinal composition is prepared from raw materials of 3 to 9 weight parts of root of red-rooted salvia and 1 to 1.5 weight parts of chingma abutilon seed. A common method for traditional Chinese medicine preparations is adopted, the Chinese medicinal composition is added into various substrates and auxiliary materials required by preparing different oral preparations to prepare oral preparations in any common formulation. Experimental results show that the root of red-rooted salvia and chingma abutilon seed composition can obviously reduce serum triglyceride, total cholesterol level, and liver triglyceride and total cholesterol content and obviously reduce liver fat lesion degree and has good treatment effect on hyperlipaemia and fatty liver. The root of red-rooted salvia and chingma abutilon seed composition has the effects of reducing serum TC and TG levels and reducing liver fat lesion superior to those of single root of red-rooted salvia and single chingma abutilon seed.

The invention discloses a heat stress-resistance Chinese herbal medicament additive for broilers and a using method thereof. The additive is prepared by mixing 1 to 5 weight parts of spine date seed oil (squeeze oil with a fatty acid content of more than or equal to 80 percent), 0.04 to 0.2 weight part of ethoxy quinoline (30 percent) and 98.96 to 94.8 weight parts of zeolite (with a water content of less than 5 percent). In use, the weight part ratio of the heat stress-resistance Chinese herbal medicament additive for broilers to compound feed or ration for broilers is 0.5-5:1,000. The additive can enhance the production performance of broilers in a heat stress period, increase feed intake and daily gain and improve feed utilization rate and dressing percentage. The additive can be used for a long term as a growth promoter and plays a significant role in the stabilization of the production performance of the broilers in summer with high temperature.

The invention discloses a preparation method of a traditional Chinese medicine capable of reducing blood lipid. The preparation method includes the steps: weighing 15-23 parts of lotus leaves, 12-20 parts of red-rooted salvia roots, 10-16 parts of root-barks of tree peony, 8-12 parts of lucid ganoderma, 10-14 parts of reed rhizome, 12-16 parts of ginseng, 16-22 parts of tuckahoe, 15-23 parts of tangerine peel, 12-16 parts of rehmannia, 14-18 parts of leonurus, 10-16 parts of honeysuckle stems, 14-20 parts of rheum officinale and 12-16 parts of dandelion by weight; adding soaked traditional Chinese herbal medicines into a decocting container, and decocting the medicines after capping the decocting container; filtering out liquid medicines after decoction to obtain an internal medicine. The preparation method has the advantages that based on the cognition and treatment principle of a hyperlipemia mechanism, a direct oral administration method is adopted, serum triglyceride and cholesterol are reduced, cardiovascular and cerebrovascular diseases are effectively prevented, treatment effects are remarkable, quality is easily controlled, stability is good, and adverse reaction is basically avoided.

The invention discloses a preparation method of a lipid-lowering corbicula fluminea shell powder compound feed. The preparation method specifically comprises the steps of firstly, adding corbicula fluminea shell powder into a basal feed for culturing fish, wherein the adding amount of the corbicula fluminea shell powder accounts for 0.75%-3.25% of the total weight of the basal feed; then uniformly mixing the basal feed, namely corbicula fluminea shell powder, to prepare particles, and drying to obtain the compound feed. The feed prepared by the invention can be used for not only lowering the index of the fish liver and serum triglyceride, but also obviously improving the activity of hepatic lipase.

The invention discloses a production method of monascus glutinous rice wine containing dietary fibers. The production method includes the steps of weighing and obtaining sticky rice, using clean waterto clean the sticky rice, and soaking the sticky rice for 1-3 hours; steaming the sticky rice till the sticky rice is cooked well, extinguishing the fire and braising the sticky rice for 10-20 minutes to obtain glutinous rice; cooling the cooked glutinous rice till the temperature of the glutinous rice is 35-38 DEG C; blending monascus with the cooled glutinous rice; putting the glutinous rice blended with monascus into a vat, carrying out sealed fermentation for 12-24 hours, then adding rice wine brewed by pure grains into the vat, putting the vat still in a shady cool dry place for sealed fermentation for 60-200 days, and controlling the temperature at 28-35 DEG C, wherein the weight ratio of the added rice wine brewed by the pure grains to the glutinous rice is (2-3):(4-5); filtering fermented substances in the vat to obtain a filtrate, and bottling the filtrate after the filtrate successfully passes examination to obtain a finished product. The monascus glutinous rice wine is simple in production process, low in production cost, capable of maintaining original medicinal effects of monascus and abundant in dietary fiber.

The invention is about the recombination plasmid containing the PON gene and its application. The recombination plasmid, the cell and the compound can prevent and cure the toxic of the organophosphor, hyperlipemia, atherosclerosis, glycuresis.

The morning taken Tibetan medicine for treating diabetes is prepared with 18 kinds of Chinese medicinal materials, including bear bile, saffron, artificial musk, amur barbery bark, etc. The preparation process includes grinding all the medicine materials into fine powder, mixing in certain weight proportion and other steps. It is prepared into medicine powder, and may be also prepared into bolus, capsule, soft capsule or granule. It can reduce blood sugar and reduce serum triglyceride and has also obvious curative effect on nephrosis.

The invention discloses a preparation method of a corbicula fluminea juice lipid-lowering compound feed for fishes, wherein the preparation method specifically comprises the steps: firstly, adding a corbicula fluminea boiled juice extract into a fish culture basic feed, wherein the addition amount of the corbicula fluminea boiled juice extract is 0.25%-1.35% of the total weight of the basic feed; and then mixing the basic feed and the corbicula fluminea boiled juice extract evenly, preparing into particles, and drying to obtain the product. The prepared feed not only can significantly reduce the fatness and the liver index of fish bodies, but also can significantly reduce the content of serum triglyceride and total cholesterols.

The invention relates to a drug used for reducing blood fat, and a preparation method thereof. The drug is used for treating hyperlipidemia and / or atherosclerosis. The drug is capable of increasing the uptake ratio of hepatocytes on low density lipoprotein, and reducing serum total cholesterol, serum triglyceride, and serum low density lipoprotein cholesterol of mouse obviously; the effect of the drug is similar to that of simvastatin; it is shown that the drug possesses excellent blood fat reducing activity, and can be used in treatment of hyperlipidemia and atherosclerosis.

The invention discloses a traditional Chinese medicinal composition for reducing blood lipid, which is prepared from the following raw materials in parts by weight: 15-20 parts of Panax notoginseng, 30-35 parts of Salvia miltiorrhiza, 30-35 parts of Ginkgo biloba leaf, 15-20 parts of Semen Cassiae, 25-30 parts of Radix Puerariae, 15-20 parts of Silybum marianum, 15-20 parts of Astragalus membranaceus,5-10 parts of Benincasa hispida peel, 10-15 parts of Bletilla striata, 2-6 parts of Solanum surattense, 10-15 parts of Radix Glycyrrhizae, and 5-10 parts of Herba Artemisiae Scopariae. The preparation method includes reflux-extracting with ethanol, drying, granulating and encapsulating. The traditional Chinese medicinal composition disclosed by the invention uses pure natural Chinese medicinal herbs to achieve blood lipid reducing and regulating effects by synergistic action.

A production method of red starter and glutinous rice wine with effects of promoting blood circulation to remove blood stasis and promoting lochia discharge comprises the following production steps: (1) glutinous rice is weighed, washed with clear water and soaked for 1-3 h; (2) the glutinous rice is steamed and then braised for 10-20 min after heat is turned off, and glutinous rice meal is obtained; (3) the steamed glutinous rice meal is air-cooled to 35-28 DEG C; (4) a red starter is blended with the air-cooled glutinous rice meal; (5) the red starter and glutinous rice meal blend is pouredinto a jar and subjected to sealed fermentation for 12-24 h, then rice wine made from pure grains is added, and sealed fermentation is performed for 60-200 d; (6) a fermented material in the jar is filtered, a filtrate is taken, and a wine liquid is obtained after inspection qualification; (7) treated medicinal materials are added to the wine liquid and soaked in a sealed manner for 120-365 d; (8)the wine liquid is separated from the medicinal materials, the wine liquid obtained through separation is bottled and sealed, and a product can be obtained. The production method of the red starter and glutinous rice wine is simple and has the effects of promoting blood circulation to remove blood stasis and promoting lochia discharge, production cost is low, and original efficacy of the red starter can be maintained.

The invention discloses functional-oligosaccharide-containing saccharose-free hawthorn coils, a preparation method therefor and application of the functional-oligosaccharide-containing saccharose-free hawthorn coils. In view of the current situation that the traditional hawthorn coils are too high in saccharose content, functional oligosaccharides are selected or are compounded with xylitol so as to replace saccharose, and the functional-oligosaccharide-containing saccharose-free hawthorn coils are prepared according to production process flows of the traditional hawthorn coils. The hawthorn coils disclosed by the invention have the functions that constipation and obesity preventing effects of the hawthorn coils are surveyed by taking diphenoxylate-hydrochloride-induced mouse constipation models and high-fat high-fructose feed induced mouse obesity models, and the action of improving defecation parameters of constipation mice and regulating lipid metabolism of obese mice is more remarkable (P is smaller than 0.05). In summary, the hawthorn coils provided by the invention are saccharose-free, are suitable for being properly eaten by people suffering from hyperglycemia, hyperlipemia and hypertension and have the functions of preventing constipation and obesity.

The invention relates to the field of medical science, in particular to an extract of total flavonoids from Mirabilis root for preventing and treating type 2 diabetes and its complications, as well as its preparation method and application. In the extract, the content of total flavonoids is greater than 40%. When the dosage of the extract is 100mg / kg, it has obvious effects of lowering blood sugar, total cholesterol, triglyceride, tissue triglyceride content and increasing glycogen content. Effect, preventive and therapeutic administration have similar hypoglycemic and lipid-lowering effects on streptozotocin-induced type 2 diabetes, and can also reduce blood sugar and blood lipids in gene knockout type 2 diabetes (db / db) mice, and Does not affect glucose and lipid metabolism in normal mice. The preparation method of the total flavonoids extract of Mirabilis root provided by the present invention adopts macroporous adsorption resin to separate and purify the total flavonoids of Mirabilis root, and in the prepared total flavonoids extract of Mirabilis root, the content of total flavonoids is greater than 40%, and the transfer rate reaches 70%, the yield can reach 2%.

The invention discloses an oral medicine for regulating blood fat, raising adiponectin and protecting liver. The oral medicine is made of the extract of the aerial part of ginseng ginseng as an active ingredient, and the total saponin content in the extract of the aerial part of ginseng ginseng is 80.10% to 92.01%, of which ginsenoside Rb 2 The content is 16.12%~28.89%, ginsenoside Rb 1 The content is 2.17%~7.10%, ginsenoside Rg 1 The content is 3.73%~9.32%, ginsenoside Rb 3 The content is 2.28% to 7.01%, and the content of ginsenoside Rd is 30.58% to 59.07%. The medicine of the present invention has no toxic and side effects, can significantly reduce body weight, reduce abdominal fat; significantly reduce serum total cholesterol, serum triglyceride, and serum low-density lipoprotein, can prevent and treat fatty liver, and reduce drug-induced liver damage; in addition, it can increase serum lipids Linkin has a positive effect on the prevention of cardiovascular and cerebrovascular diseases and diabetes.