The invention relates to a self-controlled efficient and electrostatic-spraying pesticide application machine for greenhouses, and the machine provided by the invention comprises a spraying dolly, a pesticide supply system, a pressure fluctuation elimination system, an HMI-PLC (human-machine interface-programmable logic controller) human-machine interactive automatic logic control system, a rotating electrostatic spray system, a high-definition mistform vedio monitoring system, a machine frame and a power supply system, wherein the pesticide supply system, the pressure fluctuation elimination system, the HMI-PLC man-machine interactive automatic logic control system, the rotating electrostatic spray system and the power supply system are arranged in a spraying dolly shell (42); the high-definition mistform vedio monitoring system is arranged at the top of the spraying dolly; and the HMI-PLC man-machine interactive automatic logic control system is connected between the pesticide supply system and the rotating electrostatic spray system by virtue of a pipeline. By using the machine provided by the invention, on the premise of ensuring the pest control effect, the utilization rate of pesticides is improved, the pest control cost is reduced, the environmental pollution is reduced, the production efficiency and the social efficiency are improved simultaneously, and the labor intensity is reduced.