37results about How to "Reduce the size of myocardial infarction" patented technology

The invention discloses application of NADPH in preparation of drugs used for treating heart diseases. Research results show that NADPH can protect vascular endothelial cells, maintain normal vascular permeability and reduce myocardial damage; through research on administration of exogenous NADPH for treatment of myocardial damage, novel application NADPH in treatment of heart diseases is found out.

The invention discloses a traditional Chinese medicine composition for treating chronic cardiac failure and a preparation method thereof, applied to the field of traditional Chinese medicines. The traditional Chinese medicine composition comprises traditional Chinese medicine main ingredients and medicinal auxiliary materials, wherein the traditional Chinese medicine main ingredients comprise astragalus, cassia twig, salvia miltiorrhiza, Chinese angelica, ginseng, red flower, motherwort, semen lepidii, poria cocos and pseudo-ginseng; and the medicinal auxiliary materials comprise dextrin, starch and lactose. The preparation method comprises the following steps: heating, refluxing and extracting astragalus, ginseng, pseudo-ginseng, poria cocos, salvia miltiorrhiza and semen lepidii according to a prescription ratio by using ethanol twice, filtering, merging the filtrate, and recovering ethanol to obtain liquid medicine; soaking cassia twig, red flower, motherwort and Chinese angelica according to the prescription ratio, adding the obtained medicine residue, decocting by using water, filtering to obtain liquid medicine, decocting by using water, filtering to obtain liquid medicine, and collecting distillate twice to obtain the liquid medicine; performing spray drying on the concentrated solution, and preparing extract powder; and adding the extract powder into dextrin, uniformly mixing, wetting the granules by using ethanol to obtain a finished preparation. By adopting the method for tonifying qi, promoting blood circulation to remove blood stasis and warming yang to promote diuresis, the clinical symptoms of heart failure patients are improved, the myocardial contractility can be improved, and the pumped blood of venous return is increased, so that the heartbeat is increased, and the myocardial infarction range is narrowed.

A Chinese medicine in the form of tablet, capsule, softgel, dripping pill, particles, oral liquid, or injection for treating coronary sclerosis, coronary heart disease and myocardial ischemia is prepared from red sage root, red ginseng, ophiopogon root, and schisandra fruit through extracting, proportional mixing and shaping. Its advantage is sure curative effect.

The invention provides a dispersible tablet containing effective parts of salvia miltiorrhiza and notoginseng and a preparation method thereof, which is composed of total salvianolic acid, total saponins of notoginseng, filler, disintegrating agent and other auxiliary materials, wherein the total salvianolic acid (containing The weight ratio of salvianolic acid B (not less than 60%) to total saponins of notoginseng (containing not less than 60% of total saponins of notoginseng) is 1:0.5-2. Total salvianolic acid and total saponins of notoginseng: filling agent, disintegrating agent and other excipients at a ratio of 1:1-5. The preferred ratio is 1:2-3. Disintegrant: Filling agent is 1:2-6. The preferred ratio is 1:3-5. The invention provides a dispersible tablet composed of effective parts of a compound traditional Chinese medicine, which has high technical content, clear medicinal substance basis, advanced dosage form, quick onset, strong action and high bioavailability, and is suitable for treating cardiovascular system diseases.

The invention provides a process for preparing bee glue flavone extract, its medicinal preparation and novel medical use, wherein the preparation process comprises, freezing and crushing the bee glue into coarse powder, charging in alcohol proportionally for lixiviating, filtering and combining the filter liquor, reclaiming the solvent by depression, condensing into thick grease, decompressing and drying, disintegrating into fines, dissolving by chloroform-ethanol miscible liquid, and extracting with sodium-hydroxide solution of equal volume, adjusting pH to 4-8 by charging in hydrochloric acid into alkaline extract liquor, obtaining deposition, filtering by suction, rinshing to neutral, decompressing and drying, disintegrating into fines, thus the product according to the invention can be obtained.

The invention relates to a medicinal composition for improving blood circulation and relieving stasis, wherein the composition is prepared from the following raw materials (by weight portion): panax notoginseng saponins 10-200 parts, red sage root 125-2500 parts, the invention also relates to the process for preparing the composition and use thereof.

The invention belongs to the field of medicines, and discloses a pharmaceutical composition used for treating cardiovascular and cerebrovascular diseases. According to the pharmaceutical composition provided by the invention, prasugrel or a pharmaceutically acceptable salt thereof, and carvedilol or a pharmaceutically acceptable salt thereof are adopted as pharmaceutically active ingredients. Carvedilol or the pharmaceutically acceptable salt thereof is calculated according to carvedilol, and prasugrel or the pharmaceutically acceptable salt thereof is calculated according to prasugrel. In the pharmaceutical composition, the weight ratio of carvedilol to prasugrel is 1:0.01-100, and preferably 1:0.2-20. When the pharmaceutical composition is applied in treating cardiovascular and cerebrovascular diseases, the effect is comprehensive, the toxic and side effects are low, and patient compliance can be improved. Therefore, the pharmaceutical composition has good medical application prospect.

A myocardial peptide, which is a polypeptide extracted from the heart of mammal other othan man and contains polypeptide, free amino acid, RNA and DNA, the method for testing its bioactivity, and its application in preparing the medicines for treating cardiovascular disease and reparing the damaged cardiac muscle are disclosed.