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35results about How to "Restore functionality" patented technology

Procedure to regenerate articular cartilage in human advanced osteoarthritis using autologous hematopoetic stem cell transplantation

InactiveUS20070264238A1Stop inflammatory processRecovery functionOrganic active ingredientsBiocideAntigenRegimen
A procedure for regenerating cartilage in a patient's joint damaged by Osteoarthritis by transplanting autologous hematopoetic stem cells extracted from a human, preferably the same human. The procedure begins by screening to ensure that the patient is a suitable candidate, then preparation of the patient for the stem cell transplantation by a combined regimen of intra-articular injection to diminish inflammation and facilitate apoptotic cell clearance, plus subcutaneous injection of hematopoetic growth factor. The autologous hematopoetic stem cells are then purified by incubating a blood sample with magnetic polystyrene beads (Dynabeads™) coated with a monoclonal antibody specific for CD34 cell membrane antigen. The stem cells are separated from the blood sample using a magnetic particle separator, and washed through a plurality of washing substeps. The purified and separated stem cells are suspended in a particular transplant solution, and the transplant solution is injected into the patient's joint such that the purified and separated autologous hemotopoetic stem cells enter the patient's damaged joint, and regenerates. The transplant solution contains specific growth factors that direct the stem cells into the areas of damaged or absent cartilage, allowing the stem cells to differentiate into young chondrocytes. This produces new healthy cartilage with a high potential in restoring the integrity and functionality of the joint.
Owner:SHAW ROBERT A +1

Electromechanical-hydraulic piston actuator and brake system

The invention relates to an electromechanical-hydraulic piston actuator (2) for providing pressurized pressure medium for a brake system of a vehicle, comprising an electric motor (6) having a statorand a rotor (10), a rotation-translation gearing (32) which is driven in rotation by the electric motor (6) and which has a rotatable nut (40) and a threaded rod (48) that is prevented from rotating and mounted so as to be able to slide in its axial direction, a piston (50) coupled to the threaded rod (48) in the axial direction thereof, a hydraulic cylinder (58) with a hydraulic chamber (56) which is filled with pressure medium and into which the piston (50) can be displaced, by a translatory movement of the threaded rod (48), from a retracted piston position in the direction of an advanced piston position in order to pressurize the pressure medium and / or expel same from the chamber (56), and a hydraulic connection (60) which is connected to the chamber (56) and via which pressure mediumcan be expelled from the chamber (56), and a supporting structure (3) to which the electric motor (6), the rotation-translation gearing (32) and the hydraulic cylinder (58) are attached, there being provided, between the rotor (10) of the electric motor (6) and the nut (40), an isolation device (70) for piston-travel-controlled isolation of the rotary coupling.
Owner:CONTINENTAL AUTOMOTIVE TECH GMBH

Calcineurin inhibitors for use in the treatment of lesional vestibular disorders

ActiveUS20150057233A1Reducing or alleviating at least one adverse effectAmelioration of the subject's conditionBiocideSenses disorderDiseaseVestibular disorders
The present invention relates to a calcineurin inhibitor for use in the treatment of a lesional vestibular disorder.
Owner:INST NAT DE LA SANTE & DE LA RECHERCHE MEDICALE (INSERM) +1

Magnetic field interaction device of magnetic resonance physiotherapy instrument

PendingCN108042919AThe finer the physiotherapy position, the better the effectFiner effectMagnetotherapy using coils/electromagnetsVibration massageResonanceInteraction device
The invention discloses a magnetic field interaction device of a magnetic resonance physiotherapy instrument. The magnetic field interaction device includes a pedestal, a strong magnetic ring and an inductor, the top of the pedestal is provided with a physiotherapy couch main couch body, the top of the physiotherapy couch main couch body is provided with a couch plate, the joint of the pedestal and the physiotherapy couch main couch body is provided with a sliding rail, one side of an end part of the sliding rail is provided with a drive motor, the top of the sliding rail is provided with a magnetic ring fixing plate, the magnetic ring fixing plate is slidably connected with the sliding rail, the top of the magnetic ring fixing plate is provided with a rotary magnetic disc motor, an end part of an output shaft of the rotary magnetic disc motor is connected with a rotary magnetic disc, one side of the rotary magnetic disc is provided with the strong magnetic ring, a first sliding grooveis arranged between the physiotherapy couch main couch body and the couch plate, and the strong magnetic ring is arranged inside the first sliding groove and is movably connected with the first sliding groove. The magnetic field interaction device of the magnetic resonance physiotherapy instrument enhances magnetic field resonance through a rotary magnetic field technology, so that multielement magnetic field adjustment enables the physiotherapy position of a magnetic resonance physiotherapy instrument user to be finer and effects are better.
Owner:ZHUHAI ZHENGMAI HEALTH TECH CO LTD
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