35results about How to "Suitable for clinical needs" patented technology

The invention discloses a medical nanofiber reinforced hydrophilic composite material as well as a preparation method and application thereof. The composite material is prepared from a hydrophilic basis material and nano staple fibers, wherein the nano staple fibers are maintained in crystal morphology and are uniformly dispersed in the hydrophilic basis material; the mass percent of the nano staple fibers in the composite material is 1 to 30 percent; the nano staple fibers have the diameters of 200nm to 800nm and the lengths of 10mu m to 100mu m; according to the preparation method of the medical nanofiber reinforced composite material, which is provided by the invention, the technological design is peculiar; the nano staple fibers are uniformly dispersed in the basis material by utilizing the solubility difference of the basis material and the nano staple fibers; the multicellular spongy composite material is obtained by adopting a freeze drying method; the composite material keeps the respective advantages of two materials; defects are complementary; the composite material which is excellent in mechanical performance, good in biocompatibility and good in biodegradability is obtained, and the medical nanofiber reinforced hydrophilic composite material is moderate in degradation cycle, cannot cause a postoperative inflammation and the postoperative risk of adhesion, is more suitable for clinical demand.

The invention relates to a proximal femur locking bone fracture plate. The proximal femur locking bone fracture plate comprises a top side surface, a bottom side surface used for being contact with a femur, and a group of through holes, wherein the top side surface is of an arc-shaped structure, at least one through hole is formed by the superposition parts of a pressing hole and a threaded hole, the pressing hole is a circular and thread-free, and an antibiotics layer is arranged on the inner side of the threaded hole. The proximal femur locking bone fracture plate provided by the invention has the advantages that the structure is simple, the safety is high, clinical demands are met, the bending strength of the bone fracture plate is high, when in use, locking screws can be screwed into quickly, the purpose of connecting bones more firmly is realized, in addition, the antibiotics layer covers on the inner wall of the threaded hole, a stronger antibacterial effect is realized, and the healing of fracture bones is accelerated.

The invention relates to a fibula locking bone plate which comprises a stem body mainboard and a side wing mainboard. The stem body mainboard is a recessed arc-shaped strip-shaped fixing plate, the side wing mainboard is a recessed arc-shaped fixing plate, the recessed radian of the stem body mainboard is the same as the recessed radian of the side wing mainboard, the stem body mainboard is provided with three or more first locking screw holes, the side wing mainboard is provided with four second locking screw holes and further provided with three Kirschner wire holes, and one end of the stem body mainboard disconnected with the side wing mainboard is also provided with a Kirschner wire hole. Through the design of the matching of the stem body mainboard and the side wing mainboard and the fibula of the human body, the locking bone plate adheres to the fibula better after being installed, the damage to a patient is reduced, and the healing speed is improved.

The present application discloses an extra-articular universal locking plate for the proximal end of the femur, which includes a body for fixing the proximal end of the fracture and a head for fixing the distal end of the fracture, the head and the body are integrated, the The body is bent to form a certain arc in the plane where it is located, and a plurality of coupling holes are distributed in an array on the body, and the head is concave, and two locking holes are opened on it. The extra-articular universal locking plate of the proximal femur provided by the new model has simple structure and high safety, and is suitable for clinical needs. Screwing in can achieve the purpose of connecting bones more firmly. In addition, there is a universal small hole on the inner wall of the threaded hole, which can have strong fixation and make the bone heal faster.

The invention provides a tumor cell heterogeneic transplantation zebrafish model, a construction method and application thereof. By implanting primary cells separated from a tumor tissue of a patientinto a zebrafish, the tumor heterogeneic transplantation model derived from the patient is obtained. According to the established tumor heterogeneic transplantation model, pathological characteristicsof human gastric cancer tissue in clinic are preserved, higher clinical correlation is achieved, the established tumor heterogeneic transplantation model can be used for systematically studying the mechanism of tumor proliferation, metastasis, diffusion and drug resistance, and tumor therapeutic drugs are effectively screened.

The invention relates to the field of natural medicine, in particular to compound phytolectin and a preparation method and application thereof. The compound phytolectin is prepared from pseudo-ginseng, eucommia ulmoides, root of kudzu vine, rehmannia, root of red-rooted salvia, kelp and silverweed cinquefoil root leaves, wherein the compound phytolectin contains the components of salvianic acid, salvia miltiorrhiza flavones, notoginsenoside, rehmannia saponin, rehmannin, laminaran, pueraria flavones and eucommia ulmoides terpene. Pharmacological experiments prove that the compound phytolectinhas an ideal therapeutical effect for hypertension, when the compound phytolectin is cooperatively used with hypotensive drugs, the antihypertensive efficacy is further strengthened and is obviously superior to exclusive use of hypotensive drugs, and the toxic and side effects such as edema of hypotensive drugs after cooperative use are greatly reduced. Moreover, the compound phytolectin is a natural preparation, is safe and reliable to use, is applicable for various types of hypertension patients, and is extremely suitable for current clinical requirements.

The invention relates to an L-oxiracetam oral instant membrane, which is prepared from 3 to 20 parts of L-oxiracetam, 40 to 70 parts of membrane-forming material, 10 to 30 parts of filter, 5 to 20 parts of plasticizer and 2 to 4 parts of corrigent, wherein the membrane-forming material is maltodextrin. The L-oxiracetam oral instant membrane can be dissolved by a small amount of saliva in the oral cavity, and can be taken without water for delivery, so administration is convenient. After being stuck to the tongue, the L-oxiracetam oral instant membrane cannot be easily spit out, and therefore is suitable for children with dysphagia. Moreover, because the L-oxiracetam oral instant membrane can be absorbed through the mucous membrane, the first pass elimination effect is prevented, the bioavailability is increased, the dosage of medication is reduced, and thereby the side effect of the medicine is reduced. A preparation method of the invention is simple, the process cost is low, and therefore the preparation method is suitable for mass production.

The invention provides a medical instrument bone plate, and belongs to the field of medical instruments for orthopedics. The bone plate includes a strip plate. Multiple threaded holes are arranged inthe center line of the strip plate. A left fixing plate is movably connected to one side of the strip plate. A right fixing plate is movably connected to the other side of the strip plate. The cross sections of the left fixing plate and the right fixing plate are of an arc structure. A fixing column is arranged on the lower edge of the left fixing plate. The end part of the fixing column is provided with an external thread. The lower edge of the right fixing plate is provided with a clamping groove matching the fixing column. The fixing column is fixed in the clamping groove through a nut. Themedical instrument bone plate is simple in structure and high in safety, is suitable for clinic demands, adopts an arc design on the surface, and can fit well with phalanges. Through the arrangementof the left fixing plate and the right fixing plate on the two sides of the strip plate, the bone plate can be prevented from displacement, and so bones can be connected more firmly and a fracture canbe healed more quickly and easily.

The invention belongs to the field of drugs, and particularly relates to a pharmaceutical composition for treating senile macular degeneration. The pharmaceutical composition is prepared from vitaminC, a distylium racemosum leaf extract, hyaluronic acid, vitamin E, xanthophyll, astaxanthin, zinc oxide, zeaxanthine and copper gluconate, and is preferably prepared into tablets, capsules, pills, granules, powder and suspensions. A pharmacodynamic experiment proves that the pharmaceutical composition has a better therapeutical effect on the senile macular degeneration, is good in safety and low in therapeutical cost, and is very suitable for the current clinical demands.

The invention provides an operative bone drill, belongs to the technical field of medical instruments, and aims at solving the problem that a traditional open type bone taking operation mode is single, and the damage to a patient is large. The bone drill comprises a handle, a connector, a locking screw, movable teeth, a drill rod and an adjusting sealing cap. The locking screw is fixedly arrangedon the handle; the connector is fixedly arranged at one end of the locking screw; one end of the drill rod is integrally provided with a ratchet wheel, and the other end is provided with sawteeth; thedrill rod is movably arranged on the connector, and the ratchet wheel is located in the connector; and the movable teeth are hinged in the connector, and a ratchet matched with the ratchet wheel is integrally arranged on the movable teeth. The bone drill is simple in design and operation, high in safety, high in stability and suitable for clinical requirements, and achieves the purposes of smallsurgical incision and convenience and quickness in surgery.