309results about How to "Physical stability" patented technology

The present invention provides isolated monoclonal antibodies that specifically bind LAG-3, and have optimized functional properties compared to previously described anti-LAG-3 antibodies, such as antibody 25F7 (US 2011/0150892 A1). These properties include reduced deamidation sites, while still retaining high affinity binding to human LAG-3, and physical (i.e., thermal and chemical) stability. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided, as well as immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies. The present invention also provides methods for detecting LAG-3, as well as methods for treating stimulating immune responses using an anti-LAG-3 antibody of the invention. Combination therapy, in which the antibodies are co-administered with at least one additional immunostimulatory antibody, is also provided.

Microcapsules for use in liquid detergents having a core and a polyelectrolyte complex shell in the form of a semipermeable membrane capable of withstanding a force before bursting of from about 20 mN to about 20,00 N and having a density of from about 900 Kg/m³ to about 1,300 Kg/m³ at 25° C. The invention also relates to a process for making the microcapsules and liquid detergents comprising said microcapsules.

The invention belongs to the field of construction materials and particularly relates to novel foam high-polymer composite and a production method. The novel foam high-polymer composite comprises 10-90 parts of thermoplastic plastics, 0.5-3 parts of plasticizer, 0.5-3 parts of flexibilizer, 0.5-3 parts of tackifier, 0.3-2 parts of internal and external lubricant, 0.5-3 parts of stabilizer, 0.5-5 parts of crosslinking modifier, 0.5-12 parts of regulator, 0.5-5 parts of foaming agent, 0.5-3 parts of filler, 0-20 parts of flame retardant, 10-90 parts of inorganic powder and pigment in proper quantity. The novel foam high-polymer composite in the technical scheme is energy-saving, emission-reducing, acid-resistant and alkali-resistant, weak in temperature sensitivity and excellent in physical and chemical performance.

The invention relates to organic carbon suspension liquid compound fertilizer and a preparation method of the organic carbon suspension liquid compound fertilizer. The organic carbon suspension liquid compound fertilizer comprises, by weight, 18.1-26.5 parts of organic carbon, 0.4-7.2 parts of nutrient substances, 10-12.5 parts of suspending agents and 25.0-33.0 parts of water. The organic carbon suspension liquid compound fertilizer can resolve the unbalanced fertilizer application state of carbon hunger of crops, is complete in nutrient, promotes better growth of the root systems of crops, improves the yield and quality of crops, effectively prevents the carbon hunger symptom of crops, and improves the adverse resistance of crops such as cold resistance, drought resistance and disease resistance.

The invention belongs to the field of building materials, and particularly relates to a resource-conserving type gray plastic foaming polymer composite material. The invention also relates to a preparation method of the composite material. The invention has the technical scheme that the resource-conserving type gray plastic foaming polymer composite material comprises thermoplastic plastic polyvinyl chloride (PVC), filler coal ash, an auxiliary heat stabilizer, a coupling agent, a compound stabilizer, an inside and outside lubricating agent, a plasticizing accelerating agent, a general foaming agent and a foaming regulator. The resource-conserving type gray plastic foaming polymer composite material can be used for utilizing the coal ash with a high added-value in a reclamation way, thus not only saving a great deal of calcium carbonate and timber resources, but also reducing environmental pollution and protecting the human health.

The invention discloses a method for classifying silicon carbide micro powder and classifying equipment of the method, which belong to the technical field of classification of micro powder. The method mainly includes steps that the silicon carbide micro powder sequentially enters at least two classifying machines which are serially connected, each classifying machine is provided with a self-suction sealing device, the classifying precision of each downstream classifying machine is higher than that of the adjacent upstream classifying machine, a cyclone collector is connected with the tail-end classifying machine and collects sorted silicon carbide micro powder; a bag dust collector collects waste discharged from the cyclone collector, and a system is powered by an induced draft fan disposed on a downstream of the bag dust collector. By the aid of the method and the classifying equipment, technical problems that in the prior art, the classifying precision of silicon carbide micro powder is low, extraction rate of fine powder is low, distribution of granularities of finished products is wide are solved. In addition, the method and the classifying equipment are widely applied to finely classifying silicon carbide grains.

The invention discloses a method for treating arsenic-containing wastewater by using a multiphase Fenton system based on iron oxide. The method is characterized in that firstly, the pH of the arsenic-containing wastewater is adjusted to range from 2.0 to 9.0, then an iron oxide catalyst and a hydrogen peroxide oxidizing agent are added, so that an organic arsenic compound completes form transformation from organic arsenic to inorganic arsenic in the multiphase Fenton system based on the iron oxide, meanwhile, released inorganic arsenic forms Fe-As chemical coordinate bonds through binding state iron central atoms on the surface of the iron oxide to be effectively adsorbed, and the arsenic pollutant in the arsenic-containing wastewater is removed. Degradation from organic arsenic to inorganic arsenic and adsorption of the inorganic arsenic can be finished simultaneously in one step, the iron oxide serves as an efficient adsorption material of the inorganic arsenic as well as a Fenton reaction catalyst for degrading the organic arsenic to the inorganic arsenic, and the treatment cost of the organic arsenic wastewater is effectively reduced while the reaction efficiency and the operation simplicity are greatly improved.

The invention discloses an air filtration glass fiber cotton composite material of series F5-F9. The air filtration glass fiber cotton composite material comprises non-woven cloth and a glass fiber cotton layer combined on the surface of the non-woven cloth through an adhesive material, wherein the non-woven cloth is 0.05-0.1mm thick; the glass fiber cotton layer is 0.25-1.5 mm thick and consists of glass fiber cotton with the diameter of 0.75-1.25 microns; the adhesive material is acrylic resin. A method for preparing the composite material comprises the steps of mixing and smelting proper amount of zinc oxide, borax, white sand, potash feldspar powder, pure alkaline, calcite, potassium carbonate and barium carbonate, performing primary fiber forming and then dragging the fibers through high-temperature and high-speed air flow to obtain the glass fiber cotton; dispersing the glass fiber cotton on the surface of the non-woven cloth, spraying glue, and drying to obtain the product. The air filtration glass fiber cotton composite material disclosed by the invention is high in intensity and high in filtration performance and has wide application prospects; due to the preparation method, the performance of the air filtration glass fiber cotton composite material can be further guaranteed.

The invention discloses health-care nutritive porridge, which is prepared from the following raw materials in part by weight: main materials: 70 to 80 parts of rice, additional materials: 2 to 4 parts of Chinese date pulp, 1.5 to 3 parts of medlar, 2 to 4 parts of big black beans, 1 to 2 parts of almond, 2 to 3 parts of walnut meat, 2 to 3 parts of rhizoma dioscoreae, 1 to 3 parts of lotus seed pulp and 1 to 2 parts of crystal sugar. Through elaborate allocation and complementation of each other, the health-care nutritive porridge contains multiple vitamins, has the effects of strengthening physique and improving immunity, can also supplement the spleen and invigorate the stomach, invigorate the circulation of blood and stop bleeding, and has the effects of prolonging life, nourishing skin, nourishing brain, nourishing kidney, balancing blood sugar and the like after long time use. Moreover, the health-care nutritive porridge can make body strong and young for long-term use, is optimum food for the old and the young and is a pure natural non-pollution product.

The invention provides a water-soluble composite fertilizer with high phosphorus and calcium. The composite material comprises, by weight, 10-60 parts of a potash fertilizer, 10-60 parts of a phosphate fertilizer, 10-30 parts of a calcium fertilizer, 2-20 parts of urea and 0.1-5 parts of an anti-caking agent. The invention also provides a preparation method of the water-soluble composite fertilizer with high phosphorus and calcium. The composite fertilizer has the characteristics of high content of total nutrients, stable physical and chemical properties, good powder fluidity, no caking, precipitation or gas bloating at high temperature, low temperature or normal temperature, and good solubility. Phosphoric acid or phosphate is added to a solution obtained by dissolving the composite fertilizer in water to provide an acidic condition in order to make phosphate radicals and calcium ions simultaneously stably coexist in a liquid phase and avoid the generation of calcium phosphate and other insoluble precipitates. The water-soluble composite fertilizer effectively improves the fertilizer utilization rate, has highly concentrated nutrients, is suitable for large-area automatic fertilization, can obviously improve the fertilizing efficiency, and also has the advantages of time saving, labor saving, fertilizer saving and fast fertilizer efficiency.

The invention discloses a vanadium-contained semimetallic brake block. The vanadium-contained semimetallic brake block includes, by weight, 5-7 parts of red copper fibers, 3-6 parts of potassium hexatitanate whiskers, 4-5 parts of barium sulfate, 15-25 parts of ferrovanadium powder, 4-6 parts of frictional powder, 13-15 parts of short stainless steel fibers, 6-10 parts of graphite, 2-4 parts of cellulosic fibers, 7-9 parts of coke blacking, 1-5 parts of modified resin nitrile fibers, 3-7 parts of chromite ore fine, 1-5 parts of nitrile rubber, 5-9 parts of ceramic adhesive agents and 8-10 parts of spray-bounded aluminum silicate fibers. The brake block obtained by material mixing, steel backing treatment, press molding, heat treatment, packaging and storage is low in wear rate, not prone to being dusty, high in density, good in heat dissipation, small in vibration, low in noise and high in corrosion resistance. The whole manufacturing process is simple, stability is good, cost is low and the cost-performance ratio is high.

The invention discloses a high-efficiency biogas slurry organic suspension liquid fertilizer and a preparation method thereof. The high-efficiency biogas slurry organic suspension liquid fertilizer comprises, by weight, 21.0-42.0 parts of a biogas slurry, 6.0-9.0 parts of organic matters, 4.0-25.0 parts of a nitrogen fertilizer, 9.0-20.0 parts of a potassium fertilizer, 0.5-1.0 part of a boron fertilizer, 0.5-0.8 part of EDTA-Zn, 0.4-0.6 part of EDTA-Mn, 0.1-2.0 parts of a wetting dispersant, 0.1-2.0 parts of a thickener, 0.1-2.0 parts of an antifreeze agent and 0.1-1.0 part of a root promoter. The high-efficiency biogas slurry organic suspension liquid fertilizer is an organic-inorganic suspension liquid fertilizer, and the high-efficiency biogas slurry fertilizer is prepared by fermenting a substrate biogas slurry, so the problem of the pollution of discharge of the biogas slurry to the environment is effectively solved, the biogas slurry is transformed into valuables from wastes andis fully used, and the production cost of the liquid fertilizer is reduced. The fermented biogas slurry is used to prepare the liquid fertilizer, so the liquid fertilizer can be more rapidly dissolved in water than general products, and has the advantages of high total nutrient content, stable physical and chemical properties, and no crystallization, precipitation and stratification phenomena under high temperature, low temperature and normal temperature conditions.

A bath and its method of use are disclosed, such bath containing fluid and producing waves of sufficient size to provide exercise to a user, such bath having areas of movement in its bottom, the sequential movement of which causes such waves to move to cause the user to exercise his or her body by maintaining equilibrium in the bath.

The invention belongs to the technical field of environmental protection and particularly relates to a preparation method of intelligent magnetic noise-reducing polyurethane foam. The preparation method comprises the following specific steps: treating the surface of carbonyl iron powder with a silane coupling agent; mechanically dispersing and prepolymerizing treated carbonyl iron powder, polyhydric alcohol and a chain extender; adding a crosslinking agent, a surfactant, a catalyst and isocyanate, rapidly stirring and pouring; and under the action of an external magnetic field, enabling carbonyl iron particles to form chain structures and be arranged in a foam skeleton and foaming at room temperature to produce anisotropic magnetic polyurethane foam. The entire preparation process has specific flow and is relatively simple and convenient to operate. The magnetic polyurethane foam is prepared by a one-step foaming process, the product combines the advantages of magnetic particles and polyurethane foam, has a flexible damping characteristic and is conductive to weakening the sound so that controllable acoustic and mechanical properties are achieved and the magnetic polyurethane foam can be used as a sound-absorption noise-reducing material. The magnetic polyurethane foam can be applied in fields such as civil use, automobiles and aerospace and has higher application values.

The invention provides high-phosphorus, high-zinc and high-magnesium liquid compound fertilizer. The high-phosphorus, high-zinc and high-magnesium liquid compound fertilizer is prepared from the following raw material components in parts by weight: 3-15 parts of zinc fertilizer, 4-16 parts of magnesium fertilizer, 16-75 parts of phosphorus fertilizer, 1-15 parts of urea, 0.5-8 parts of potassium fertilizer, 0.5-4 parts of cosolvent, 0.5-4 parts of stabilizer and 10-40 parts of water. The invention also provides a preparation method and an application method of the high-phosphorus, high-zinc and high-magnesium liquid compound fertilizer. The high-phosphorus, high-zinc and high-magnesium liquid compound fertilizer has the advantages that the total nutrient content is high, physical and chemical shapes are stable, phosphorus, zinc and magnesium are stably dissolved in liquid at the same time, phenomena such as crystallization, sedimentation, layering and the like are not caused under high temperature, low temperature and normal temperature conditions, liquidity is good, nutrients are highly enriched, the high-phosphorus, high-zinc and high-magnesium liquid compound fertilizer is applicable to automatic fertilization operation in a relatively large area, fertilization efficiency can be obviously improved, foliar application and drenching can be realized, and the high-phosphorus, high-zinc and high-magnesium liquid compound fertilizer also can be applied to a spray irrigation and drop irrigation system, is easy to use, is time-saving, labour-saving and fertilizer-saving and is quick in fertilizer effect.

The invention discloses polycarbonate/glass fiber alloy used for the cold resistant housing of an intelligent water meter and a preparation method thereof. The polycarbonate/glass fiber alloy comprises, by weight, 30 to 50 parts of PC, 30 to 50 parts of an PC recycled material, 0.3 to 0.5 part of a fireproof agent FR2025, 0.5 part to 2 parts of titanium dioxide, 9.5 to 11.5 part of glass fiber, 2 to 5 parts of EMA, 0.1 to 0.5 part of an anti-oxidant1010, 0.1 to 0.5 part of an anti-oxidant 168, 0.3 to 0.5 part of an ultraviolet resistant agent UV-531, 0.03 to 0.08 part of diffusion powder EBS, 0.04 to 0.08 part of ultramarine blue powder, 0.02 to 0.04 part of iron oxide red powder 0.005 to 0.01 part of high temperature resistant florescent yellow powder and 2 to 5 parts of a cold resisting agent 2602. The alloy has the characteristics of high performance, high cold resistance, high fire retardancy, high impact, high stability, resistance to static electricity and the like, and can be used for preparing the housing of intelligent water meters used in chilly regions and for preparing terminal rows.

The invention belongs to the medicinal preparation field, and relates to faropenem sodium freeze-drying powder and a preparation method thereof. The invention provides the faropenem sodium freeze-drying powder with simple preparation, controllable quality, stable and physical and chemical properties and safe and effective use, wherein the freeze-drying powder contains 0.1 to 10 weight percent of faropenem sodium, 3 to 25 weight percent of excipient and 0.005 to 3 weight percent of antioxidant. The stability of the faropenem sodium freeze-drying powder prepared by a freeze-drying process is greatly improved, quality indexes of related substances, polymers and the like of main medicaments are well controlled, and the administration safety is improved.

The invention relates to a medicinal composition. The medicinal composition comprises sitagliptin, pharmaceutically acceptable salt thereof and/or hydrate of the salt, and anhydrous calcium hydrogen phosphate. The medicinal composition is further used for preparing a solid preparation, and is especially prepared into a tablet by a direct tabletting method. Through selection of the medicinal composition, especially selection of the specific anhydrous calcium hydrogen phosphate as a raw material, the quality control way of the medicinal composition using the sitagliptin, the pharmaceutically acceptable salt thereof and/or the hydrate of the salt as an active component can be significantly improved, and even production of related impurities in the medicinal composition can be significantly improved so as to improve the stability of the medicinal composition and relevant dosage forms.

An ultraviolet ray and infrared ray-absorbing glass composition includes the following basic glass components (weight ratio): 60% to 75% of SiO₂, 8% to 20% of Na₂O, 3% to 12% of CaO, 0.1% to 5% of Al₂O₃, 2% to 5% of MgO, 0.02% to 7% of K₂O, 0.1% to 5% of BaO, 0.01% to 0.4% of SO₃ and the following ultraviolet ray and infrared ray-absorbing glass main body coloring and coordinating part: 0.22% to 1.35% of Fe₂O₃, 0.001% to 0.8% of ZrO₂+HfO₂, 0% to 0.5% of Cl, 0% to 2% of B₂O₃, 0.01% to 0.8% of TiO₂, 0.001% to 0.06% of CuO, 0% to 2.0% of Br, 0% to 0.02% of MnO, 0% to 2.0% of F, 0.001% to 0.5% of SrO, and 0.005% to 2.2% of CeO₂. The reduction oxidation ratio of Fe₂O₃ in the glass composition is 0.4 to 0.8.

The invention provides an electrolytic aluminum prebaked anode anti-oxidation insulating coating. The electrolytic aluminum prebaked anode anti-oxidation insulating coating comprises the following components in percentage by mass: 60%-75% of a main component, 0.01%-5% of a secondary component, 24%-34% of a nano solvent binding phase and 0.01%-5% of a coating stabilizing phase, wherein the main component comprises amorphous aluminum oxide, nano-scale rho-Al2O3, nano-scale gamma-Al2O3 and nano-scale alpha-Al2O3. The insulating coating prepared by the invention can be cured at normal temperaturefor 6-8 hours after being sprayed to an anode by a spraying machine, the anode coating can form a compact net-shaped structure at the working temperature of 500-800 DEG C, the long-term tolerable temperature is over 900 DEG C, and the physical and chemical properties are stable.

The invention provides a micro emulsion and process for preparation, wherein the mass ratio being LAS 1.0-3 parts, AES1.5í½4.5 parts, butanol 7.5-22.5 parts, mixed benzol 10-30 parts and water 55-165 parts.