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41results about How to "The reaction process is mild and easy to control" patented technology

Preparation method of lithium bis (fluorosulfonyl) imide

The invention discloses a preparation method of lithium bis (fluorosulfonyl) imide. The preparation method comprises the following steps: (1) in the presence of an ammonia source, an organic solvent,fluoride salt and an initial amount of sulfuryl fluoride, slowly introducing organic alkali while continuously introducing the balance of sulfuryl fluoride until the reaction is finished, and directlycarrying out reduced pressure distillation on the reaction solution to obtain an intermediate, namely the difluorosulfonyl imide salt; and (2) in the presence of an organic solvent, adding lithium oxide powder into the intermediate imidodisulfuryl fluoride salt, filtering, concentrating, adding a non-aqueous poor solvent, and crystallizing to obtain lithium bis (fluorosulfonyl) imide.
Owner:SHANGHAI HUAYI GRP CO +1

Preparation method for hypophosphorous acid / phosphorous acid/ phosphate compounds by adopting P(O)-OH-contained compounds

The present invention provides a highly selective synthesis method for hypophosphorous acid / phosphorous acid / phosphate derivatives containing different substituted functional groups. In the present invention, base is adopted as a catalyst, compounds containing P(O)-OH and halogenated aliphatic hydrocarbons are adopted as reaction substrates, and an organic solvent is added into the reaction system. The method has advantages that the catalyst is cheap and easily obtained; reaction conditions are mild, safe and reliable; the selectivity of target product is close to 100%, and the yield is up to 90%. According to the present invention, the problems of low reaction selectivity, tedious reaction steps, low yields, needing reagents harmful to environment and the like in conventional methods for synthesizing hypophosphorous acid / phosphorous acid / phosphate compound are solved. The method has good industrial application prospects. The present invention also provides the corresponding hypophosphorous acid / phosphorous acid / phosphate derivatives containing different substituted functional groups.
Owner:HUNAN UNIV

Preparation method of organic silicon modified polyether polyol

The invention provides a preparation method of organic silicon modified polyether polyol. The preparation method comprises following steps: step one, preparing terminal hydrogen containing silicone oil; step two, preparing allyl polyether; and step three, preparing organic silicon modified polyether polyol. The preparation method has the advantages that the structural characteristics of common polyether polyol are maximally preserved; the speed of reactions between modified polyether polyol and isocyanate is similar with that of reactions between common polyether polyol and isocyanate; modified polyether polyol can completely or partially replace common polyether polyol; modified polyether polyol can be used with polyester polyol to synthesize polyurethane, moreover, the reaction process is mild and easily controllable, the synthesized polyurethane is used to paint a material, the coated material is smooth and has a good wear resistant performance, and no surface migration happens.
Owner:江西三越新材料有限公司

Method for preparing organic lactone by catalyzing and oxidizing organic ketone with carbon materials

The invention provides a method for preparing organic lactone. The method is characterized in that carbon materials are used as catalyst, the carbon materials may be graphite, graphene, carbon nano tube, active carbon and so on; organic ketone is used as substrate, oxygen or air is used as oxygen source, organic aldehydes materials are used as reductant, and organic solvent is added into reaction system. The method has the following advantages: the preparation for the catalyst is simple; the reaction condition is mild, secure, credible and environmental friendly; the selectivity and the yield of the obtained target products are about 100%; and the catalyst can be used repeatedly. The method solves the problem that the traditional preparation technology for lactone has poor security and low yield, and has good industrial application prospect.
Owner:HUNAN UNIV

Method for preparing organic lactone

The invention provides a method for preparing organic lactone. The method is characterized in that: cubic cobaltosic oxide is taken as a catalyst, and the catalyst is prepared with a hydrothermal method; and organic ketone is taken as a substrate, oxygen or air is taken as an oxygen source, an organic lactone substance is taken as a reducing agent, and an organic solvent is added into a reaction system. The method has the advantages that: the catalyst is easy to prepare; reaction conditions are mild, and the method is safe, reliable and environmentally-friendly; the selectivity and yield of an obtained target product are close to 100 percent; and the catalyst can be used for repeatedly. Due to the adoption of the method, the problems of poor safety, low yield and the like existing in the conventional lactone preparation process are solved, and the method has a good industrial application prospect.
Owner:HUNAN UNIV

Phenol derivative containing (Rp)-2-chiral phosphinate substituent and preparation method thereof

The invention provides a method for synthesizing a phenol derivative having a phosphorous chiral center and containing a (Rp)-2-chiral phosphinate substituent in a high stereoselectivity manner. According to the method, with small organic molecules as a catalyst and a (Rp)-2-chiral phosphinate compound containing P-H bonds, and phenol as reaction substrates, an organic solvent is added into a reaction system. The method has the advantages that the catalyst is low in cost and easy to obtain; reaction conditions are mild, safe and reliable; the stereoselectivity of the obtained target product is close to 100 percent and the yield of the obtained target product is up to 90 percent. According to the method provided by the invention, the defects of poor stereoscopic enantioselectivity, fussy reaction steps, low yield and the like of an organic phosphine compound containing the phosphorous chiral center, which is synthesized by adopting a traditional method, are overcome, and the method has a favorable industrial prospect. The invention further provides the phenol derivative having the phosphorous chiral center and containing the (Rp)-2-chiral phosphine substituent.
Owner:HUNAN UNIV

Method for preparing alpha-acyloxy ketone compound from terminal alkyne compounds

The invention provides a method for efficiently synthesizing an alpha-acyloxy ketone compound containing different substitute functional groups. According to the method, acetylacetone copper is taken as a reaction catalyst, t-butylhydroperoxide is taken as an antioxidant, ketone compounds and terminal alkyne compounds are taken as reaction substrates, and an organic solvent is added into a reaction system. The method has the advantages that the catalyst is cheap and easily available; reaction conditions are mild, safe and reliable; and the productivity of an obtained target product is relatively high. According to the method, the problem that a traditional alpha-acyloxylation reaction system is single is solved, and a novel acyloxylation reagent is provided; and the method has good industrial application prospects.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY

Phenol derivatives containing (Sp)-2-chiral phosphinate substituent groups and preparation method thereof

The invention provides a method for synthesizing phenol derivatives containing (Sp)-2-chiral phosphinate substituent groups with a phosphorus chiral center at high stereoselectivity. The method is characterized in that an organic small molecule material is taken as a catalyst, (Rp)-chiral phosphinate compounds containing a P-H bond and 2-halogenated phenol (-I, -Br) are taken as reaction substrates, and a base and an organic solvent are added to a reaction system. The method provided by the invention has the following advantages that the catalyst is cheap and easy to obtain, the reaction conditions are mild, and safe and reliable, the stereoselectivity of the obtained target product is close to 100% and the yield of the product is high; and the method overcomes the shortcomings of poor stereo enantioselectivity, complex reaction steps, low yield and the like of the traditional method for synthesizing a chiral phosphine compound with the phosphorus chiral center, and has an excellent industrial application prospect. The invention also provides phenol derivatives containing the (Sp)-2-chiral phosphinate substituent groups with the phosphorus chiral center.
Owner:HUNAN UNIV

Preparation method of N-phenyl maleimide heat-resistant modifier

The invention discloses a preparation method of an N-phenyl maleimide heat-resistant modifier. The preparation method comprises the following steps: adding styrene, maleic anhydride, azodiisobutyronitrile, trithio dimethyl carbonate and 2-methyl-dithiobenzimidazole benzyl ester to form a polymerization system; carrying out a polymerization reaction for 2-6 hours at 60-120 DEG C under nitrogen protection; then, cooling to 60 DEG C, adding aniline, acetic anhydride and sodium acetate, and raising the temperature to 100-150 DEG C to react for 2-6 hours; and finally, cooling to room temperature, pouring the reactants into ethanol to settle a polymer, and filtering and drying to obtain a finished product. Through the above manner, the molecular weight and distribution of the product of the polymerization reaction can be conveniently controlled. The molecular weight of the prepared polymer is distributed below 1.3. Comparatively speaking, the molecular weight distribution is relatively narrow, the process is relatively simple, and the N-phenyl maleimide heat-resistant modifier has a relatively high economic value.
Owner:江苏科利新材料有限公司

Novel method for preparing diarylmethyl substituted phosphonate

The invention provides a method for efficiently and highly selectively synthesizing diarylmethylphosphonate derivatives containing different substituted functional groups. According to the method, silver tetrafluoroborate is used as a catalyst, trialkyl phosphite and a 4-arylmethylene-2,6-di-tert-butyl-2,5-cyclohexadien-1-one compound are used as reaction substrates, and an organic solvent is added into a reaction system. The method has the advantages that the catalyst is cheap and easily available; substrate applicability is high; reaction conditions are mild, safe and reliable; the selectivity of the obtained target products is close to 100%; and the yield of the target products is as high as 90% or above. The method overcomes the defects of poor reaction selectivity, complex reaction steps, low yield, need for reagents harmful to the environment and the like in traditional synthesis of diarylmethyl substituted phosphonate derivatives, and has favorable industrial application prospects. The invention also provides the corresponding diarylmethyl substituted phosphonate derivatives containing different substituted functional groups at the same time.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY

Method using aryl diazonium tetrafluoroborate and nitrile to prepare organic amide compounds

The method provides a method for efficiently synthesize organic amide compounds containing different substitution functional groups in a high selectivity manner. The method is characterized in that copper iodide is used as the catalyst, aryl diazonium tetrafluoroborate compounds and organic nitrile compounds are used as the reaction substrates, and an organic solvent, water and alkali are added into the reaction system. The method has the advantages that the catalyst is cheap and easy to obtain; the substrates are high in adaptability; reaction conditions are mild, safe and reliable; the selectivity of the obtained target product is close to 100%, and the yield of the target product reaches up to 90% or above; defects that a traditional method for synthesizing the organic amide compounds is harsh in reaction condition, poor in reaction selectivity, complex in experiment steps and low in yield, needs reagents harmful to environments and the like are overcome, and the method is promisingin industrial application prospect. The invention further provides the corresponding organic amide compounds containing different substitution functional groups.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY

Recovery method of protein in high concentration protein wastewater

The invention provides a recovery method of protein in high concentration protein wastewater. Nitrogen circulation carries acetic acid into high concentration protein wastewater to adjust pH change step by step to different protein isoelectric points (pI), thus achieving graded isoelectric precipitation and recovery of protein from wastewater. The method provided by the invention adopts carry of acetic acid by pressurized nitrogen circulation as an acidic adjustment means, makes the pH value adjustment mild and controllable, can precipitate out proteins with different isoelectric points under different operation conditions respectively, thereby achieving the purpose of efficient and graded removal of protein from high concentration protein wastewater by protein isoelectric point precipitation technique.
Owner:OCEAN UNIV OF CHINA

Method for preparing organic phosphate compounds from P(O)-OH compounds and methyl-containing substituted aromatic hydrocarbons

The invention provides a high-efficiency and high-selectivity synthetic method for organic phosphate derivatives containing different substituted functional groups. The method uses tetrabutylammoniumiodide as a catalyst and uses a P(O)-OH-containing compound and a methyl-containing aromatic hydrocarbon compound as reaction substrates, and an organic solvent and an oxidant are added in the reaction system. The method has the advantages that the catalyst is cheap and easy to obtain, the substrate applicability is high, the reaction conditions are mild, safe and reliable, the selectivity of an obtained target product is close to 100%, and the yield is up to 90% or more. The method solves shortages in traditional organic phosphate ester compound synthetic methods that reaction selectivity ispoor, reaction steps are complicated, the yield is low, environmentally-harmful agents are used and the like, and has better industrial application prospects. The invention also provides the corresponding organic phosphate derivatives containing the different substituted functional groups.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY

Novel green method for preparing 2-diarylmethyl substituted-1-naphthol compound

The invention provides a method for efficiently and highly selectively synthesizing 2-diarylmethyl substituted-1-naphthol compounds containing different substituted functional groups, which adopts phosphoric acid as a catalyst, adopts 1-naphthol compounds and 4-arylmethylene-2, 6-dialkyl-2, 5-cyclohexadiene-1-ketone compounds as reaction substrates, and adopts a one-pot method to synthesize the 2-diarylmethyl substituted-1-naphthol compounds containing different substituted functional groups. The reaction system takes water as a solvent. The method has the advantages that the catalyst is cheap and easily available; the substrate applicability is high; reaction conditions are mild, safe and reliable; the selectivity of the obtained target product is close to 100%, and the yield is high. The method overcomes the defects of poor reaction selectivity, tedious reaction steps, low yield, need of reagents harmful to the environment and the like in traditional synthesis of the 2-diarylmethyl substituted-1-naphthol compound, and has a good industrial application prospect. The invention also provides the corresponding 2-diarylmethyl substituted-1-naphthol compounds containing different substituted functional groups at the same time.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY

Method for preparing 2-iodo-1-phosphoryl substituted alkane compound through efficient olefin bifunctionalization

The invention provides a method for efficiently and highly selectively synthesizing a substituted 2-iodo-1-phosphoryl substituted alkane compound containing different functional groups. N-iodosuccinimide (NIS) is used as an accelerant, a compound containing P(O)-OH and olefin are used as reaction substrates, and an organic solvent is added into a reaction system. The method has the advantages thatthe accelerant is cheap and easy to obtain; the substrate applicability is high; reaction conditions are mild, safe and reliable; the selectivity of the obtained target product is close to 100%; andthe yield is as high as 90% or above. According to the method, a new way for synthesizing the substituted 2-iodo-1-phosphoryl substituted alkane compound containing different functional groups is developed, the defects of poor reaction selectivity, complex reaction steps, low yield, need of reagents harmful to the environment and the like in traditional synthesis of the 2-iodo-1-phosphoryl substituted alkane compound are overcome, and the method has a good industrial application prospect. The invention also provides a corresponding substituted 2-iodo-1-phosphoryl substituted alkane derivativecontaining different functional groups.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY

Method for preparing C2-position alkynyl compound by catalyzing thiamine type compound desulfuration through cuprous halides

The invention provides a method for efficiently synthesizing derivatives which contain different substitution functional groups and have C2-position alkynyl substituted.According to the method, Pd(OAc)2(PPh3)2 / CuI is used as a catalyst, Na2CO3 is added as alkaline, compounds containing thiamine and terminal alkyne are used as oligomer, and organic solvent is added to the reaction system.The method has the advantages that the catalyst is low in price and easy to obtain; the reaction condition is mild, safe and reliable; the highest yield of target products reaches 92%.The method overcomes the defects that in traditional desulfuration reaction, cuprous thiophene needs to be used as a desulfurizing agent and cuprous halides can not react; the operation process is simple, and good industrial application prospects are achieved.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY

A New Method for the Efficient Preparation of Chiral Organic Phosphonates Containing r-/s-Diarylmethyl Substitutions by Chiral Induction

The invention provides a method for efficiently and high-selectively compounding chiral R- / S- diaryl methyl substituted chiral organic phosphonate derivatives containing different substituting functional groups. Cesium carbonate is taken as a catalyst; chiral P(O)-H compound and 4-aryl methylene-2,6-di-tert-butyl-2,5-cyclohexadiene-1-ketone compounds are taken as reaction substrates; an organic solvent is added into a reaction system. The method has the advantages that the catalyst is low-cost and can be easily acquired; the substrates are high in applicability; the reaction conditions are mild, safe and reliable; the three-dimensional enantioselectivity of the acquired target product is above 99% and the yield is above 80%. The method can overcome the defects of low enantioselectivity, complex reaction steps, and the like, of the traditional reaction for compounding chiral R- / S- diaryl methyl substituted chiral organic phosphonate derivatives, can avoid the traditional chiral resolution method and has an excellent industrial application prospect. The invention also provides the corresponding chiral R- / S- diaryl methyl substituted chiral organic phosphonate derivatives containing different substituting functional groups.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY

Aromatic secondary primary amine containing triaryl-s-triazine structure and ether bond and preparation method thereof

The invention discloses aromatic primary diamine containing a triaryl-s-triazine structure and an ether bond and a preparation method thereof, belonging to the technical field of synthesis of compounds. The aromatic primary diamine containing the triaryl-s-triazine structure and the ether bond has a structural formula as shown in a formula (I). The preparation method comprises the following steps: subjecting a dihalogen compound containing triaryl-s-triazine and shown in a formula (II) and a p-aminophenol compound as shown in a formula (III) to a nucleophilic substitution reaction; and then subjecting a reaction product to filtering, washing and drying so as to obtain the aromatic primary diamine containing the triaryl-s-triazine structure and the ether bond. The aromatic primary diamine containing the triaryl-s-triazine structure and the ether bond in the invention contains the triaryl-s-triazine structure with high rigidity, high thermal stability and strong polarity, so when the aromatic primary diamine is used as a monomer for synthesis of polyamide, polyimide and benzoxazine resin, the aromatic primary diamine can effectively improve the heat resistance and mechanical properties of a material and reduce the dielectric loss and water absorption rate of the material at the same time.
Owner:DALIAN UNIV OF TECH

Novel method for preparing phosphoryl azo compounds

The invention provides a method for preparing phosphoryl azo compounds with high efficiency and high selectivity; pyridine is used as alkali, an aryl diazonium tetrafluoroborate compound and a P(O)-Hcompound are used as reaction substrates, and an organic solvent is added into a reaction system. The method has the advantages that a catalyst is cheap and easily available; the substrate applicability is high; reaction conditions are mild, safe and reliable; the selectivity of the obtained target products is close to 100%, and the yield is high. The method overcomes the defects of harsh reactionconditions, poor reaction selectivity, complex experimental steps, low yield, need of reagents harmful to the environment and the like in a traditional synthesis of phosphoryl azo compounds, and hasfavorable industrial application prospects. The invention also provides the corresponding phosphoryl azo compounds containing different substituted functional groups.
Owner:HUNAN INSTITUTE OF SCIENCE AND TECHNOLOGY
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