161 results about "Isopentadiene" patented technology

The invention relates to the field of biological engineering and technology, in particular to an enzyme for synthesizing glabridin, a biological synthesis method of glabridin and a bacterial strain. The invention discloses a series of glabridin synthesizing enzymes (phenylalanine ammonialyase, cinnamic acid-4-hydrogenase, tyrosine ammonialyase, p-coumaric acid coenzyme A ligase, chalcone synthase, chalcone reductase, chalcone isomerase, isoflavone synthase, 2-hydroxyisoflavone dehydratase, 4 '-oxymethyltransferase, 4'-hydroxymethyltransferase and 4 '-hydroxymethyltransferase) derived from glycyrrhiza glabra for the first time. ) can be used in the preparation of a compound (e.g., isoflavone 2 '-hydrogenase, isoflavone reductase, Vissisoketoreductase, isoprenyltransferase, pterocarpin reductase, oxidative cyclase, demethylase, cytochrome P450 reductase, and the like). The de novo synthesis of the glabridin in a microbial cell factory is realized for the first time, and the application prospect of the glabridin biological manufacturing industry is greatly promoted.

The invention relates to the field of biological engineering and technology, in particular to an enzyme for synthesizing glabridin, a biological synthesis method of glabridin and an engineering-modified biological host. The invention discloses a series of glabridin synthesizing enzymes (4 '-O-methyltransferase, isoflavone 2'-hydrogenase, isoflavone reductase, Vissisoketoreductase, isoprenyltransferase, pterocarpin reductase, oxidative cyclase and demethylase) from glycyrrhiza glabra for the first time, and the glabridin synthesizing enzymes have corresponding activities in various biological hosts. The heterologous biosynthesis of the glabridin is realized for the first time, and the yield of the glabridin can reach 60% or above.

The present disclosure relates to recombinant microorganisms, such as bacteria, e.g., E. coli, engineered to have improved flux and / or yield of the DXP pathway. Cells can be engineered to comprise nucleotide sequences comprising dxs polypeptides (EC 2.2.1.7); dxr polypeptides (EC 1.1.1.267); ispD polypeptides (EC 2.7.7.60); ispE polypeptides (EC 2.7.1.148); ispF polypeptides (EC 4.6.1.12); ispG polypeptides (EC 1.17.7.1 or EC 1.17.7.3); ispH polypeptides (EC 1.17.7.4); and idi polypeptides (EC 5.3.3.2). Cells can be further engineered to express redox polypeptides, e.g., ferredoxins, flavodoxins, and / or flavodoxin / ferredoxin--NADP reductases (EC 1.19.1.1 or EC 1.18.1.2), e.g., to increase the activity of the ispG and / or ispH polypeptides. Some or all of the nucleotide sequences can be heterologous to the cells. The recombinant microorganisms can be used in methods of isoprenoid production.

The invention provides a method for biosynthesizing menadione by using yarrowia lipolytica. The method is realized by constructing recombinant yarrowia lipolytica, and the construction method of the recombinant yarrowia lipolytica for synthesizing menadione comprises the following steps: intensively expressing a mevalonic acid pathway in the yarrowia lipolytica, and synthesizing menadione by introducing a synthesis pathway of heterologous geranyl and geranyl pyrophosphate. A sufficient isoprene side chain donor is provided for biosynthesis of menadione; on the basis, an aromatic isopentenyl transferase coding gene which is optimized by codons and has menadione substrate specificity is over-expressed in yarrowia lipolytica. The construction method of the yarrowia lipolytica for biosynthesis of menadione provided by the invention is simple to operate, the constructed yarrowia lipolytica can obtain a menadione product with relatively high concentration by taking commercially available menadione as a substrate, the biosynthesis steps are relatively short, and the yarrowia lipolytica has relatively high production and application values.

To provide a thermosetting adhesive composition which has, after thermally cured, a low dielectric constant, a low dielectric loss tangent, a low temperature change rate of the dielectric loss tangent, and good bending resistance.SOLUTION: A thermosetting adhesive composition for bonding between substrates is provided, containing with respect to 100 pts.mass of the total of the thermosetting adhesive composition, 65 to 90 pts.mass of a styrenic elastomer, as crosslinking components, 5 to 20 pts.mass of (A) a modified polyphenylene ether resin having a radical polymerizable group at a molecular terminal, 4 to 10 pts.mass of (B) polybutadiene and / or polyisoprene having a weight average molecular weight of 10,000 to 50,000, a radical polymerization initiator, and an epoxy resin, wherein the total of the contents of the radical polymerization initiator, the epoxy resin and the epoxy resin curing agent is 10 pts.mass or less, a styrenic elastomer having a styrene ratio of less than 67% is contained as the styrenic elastomer, and the total of the content of the component (A) and the content of the component (B) is 25 pts.mass or less.SELECTED DRAWING: Figure 1

A functionalized diene polymer having at least one first functional group and at least one second functional group, wherein the first functional group is selected from end groups, side groups, and combinations thereof, the second functional group is an end group, the first functional group comprises at least one unit derived from a functionalized monomer represented by formula (1) (wherein R1, R2, and R3 are selected from hydrogen and methyl, provided that at least one of R1, R2, and R3 is hydrogen, preferably R1, R2, and R3 are all hydrogen, n is 1, 2, 3, 4, or 5, each R4 is independently selected from aliphatic residues or arylaliphatic residues having 3 to 30 carbon atoms, and R4 contains at least one tertiary amine group when n = 1, and at least one of the residues R4 contains at least one tertiary alkylamine group when n = 2 to 5); or (ii) the first functional group is obtained by using a polymerization initiator of the general formula: N(R1)(R2)(R3M) (wherein R1 and R2 are the same or different from each other and are selected from linear or branched saturated alkyls, R3 is a saturated, linear or branched alkyl carbanion, and M is an alkali cation), the second functional group is an end group, and comprises at least one group selected from -COOX; -OX; -SX (wherein X represents hydrogen or a cation), a plurality thereof, and combinations thereof. Also provided are a method for producing the polymer, an article obtained from the polymer, and a method for producing an article with the polymer, wherein the functionalized diene polymer is a homopolymer or copolymer of a conjugated diene, and the conjugated diene is selected from the group consisting of butadiene, isoprene, isoprene, 1,3-pentadiene, 2,3-dimethylbutadiene, 1-phenyl-1,3-butadiene, 1,3-hexadiene, preferably butadiene.

The present disclosure relates to the synthesis of Vitamin K2 bearing varying prenyl side chains. The synthesis comprises the reaction of phenyl sulfone of tert-butyl dimethyl silyl (TBDMS) protected mono prenyl menadiol with prenyl halides bearing varying prenyl units in the presence of the phase transfer catalyst followed by reductive desulphonation to yield TBDMS ether of Vitamin K2. The TBDMS ether is then oxidized in the presence of chromium trioxide and periodic acid to yield the corresponding Vitamin K2.

This invention discloses a lubricating grease composition, belonging to the field of lubricating grease technology. The lubricating grease is made from the following raw materials in parts by weight: 20-40 parts base oil, 10-35 parts liquid polybutadiene, 10-30 parts liquid polyisoprene, 10-30 parts liquid styrene-isoprene polymer, 4-15 parts thickener, 0.1-2 parts antioxidant, 0.1-1.5 parts rust inhibitor, and 0.5-3.2 parts extreme pressure anti-wear agent. The lubricating grease of this invention retains the basic properties of lubricating grease while ensuring high viscosity and high adhesion, as well as low-temperature fluidity. Even in a low-temperature environment of -60°C, it can ensure low-temperature start-up, low operating torque, low-temperature pumpability, and fluidity.

The invention discloses an isoprene cyclization trimerization method catalyzed by a carbon-based nickel-containing catalyst. The trimerization target product trimethyl cyclododecatriene is high in selectivity, and C16 and more by-products in the product are few.

Disclosed herein are prenylated flavone compounds having the structure of Formula (I), or a pharmaceutically acceptable salt and / or hydrate or solvate thereof. Also disclosed herein are methods for producing prenylated flavone compounds, and uses for such compounds, including in medical treatments.

The invention is related to a process for synthesizing a sustainable aviation fuel composition. The process comprises providing a reaction mixture comprising a first compound that is at least one of mevalonolactone, mevalonic acid, mevalonate salt, dehydromevalonic acid, dehydromevalonate salt, dehydromevalonolactone or combinations thereof. The process then involves converting the first compound in the reaction mixture to provide a first intermediate comprising isoprene. Then, the isoprene in the first intermediate is reacted in the presence of a first heat transfer agent to provide a second intermediate comprising terpenes. Finally, the second intermediate is allowed to react in the presence of a second heat transfer agent, or alternatively in neat conditions, and optionally in presence of a catalyst to provide the sustainable fuel composition. The sustainable aviation fuel composition made available from the process of the invention is found to comprise monocyclic aromatic hydrocarbons (MAHs) at useful concentration ranges (along with cycloalkanes) while they are substantially devoid of Polycyclic aromatic hydrocarbons (PAHs).

The invention relates to the field of molecular biology, in particular to an enzyme for cannabinoid synthesis and a method for preparing cannabinoid. More specifically, the present invention relates to a method for producing a cannabinoid phenolic acid (CBGA) or an analog thereof, the method comprising the steps of: reacting a heterologous expressed isoprenyltransferase with a geranyl diphosphate (GPP) and an acid; wherein the amino acid sequence of the isoprenyltransferase is SEQ ID No: 1, or the isoprenyltransferase is expressed by the nucleotide sequence of SEQ ID No: 2.

There is provided a recombinant cell comprising a plasmid expressing terpenoid synthase gene and one or more modification to the gene of the recombinant cell. Also provided is a recombinant cell for use in biosynthesis and a method of producing isoprenoid / terpenoid.

The object of the present invention is to provide a resin composition capable of obtaining an insulating layer having excellent thermal conductivity and peel strength to a metal layer, a resin sheet using the resin composition, a circuit board, and a semiconductor chip package. The solution of the present invention is a resin composition comprising: (A) a polymer compound having one or more structures selected from the group consisting of a polybutadiene structure, a polysiloxane structure, a poly(meth)acrylate structure, a polyalkylene structure, a polyalkyleneoxy structure, a polyisoprene structure, a polyisobutylene structure, and a polycarbonate structure in a molecule, (B) an epoxy resin, (C) a thermally conductive filler, and (D) an active ester curing agent.

The present disclosure provides compositions and methods for producing a high-purity isoprenoid from an isoprenoid composition, wherein the method includes using chromatography to reduce the impurities in the isoprenoid composition to below parts per million levels. Further provided herein are compositions containing high-purity isoprenoids.

System and processes are provided for converting glycerol to acrolein, an aldehyde to isoprene, and one or more fusel oils to isoprene. Each of this processes utilize at least one catalyst that includes a zeolite and one or more metals dopants (e.g., Group 1A metal(s), Group 2A metals(s), or any combination thereof). The at least one catalyst can optionally include one or more non-metal dopants (e.g., boron, phosphor, or a combination thereof).

The invention discloses a regulator for improving grape fruit fragrance and a preparation method thereof, and belongs to the technical field of grape cultivation, each liter of regulator comprises 50 mg-120 mg of chitosan oligosaccharide, 20 mg-50 mg of sodium selenite, 10 mg-20 mg of jasmonic acid methyl ester, 100 mg-250 mg of green tea polyphenol, 10 mg-20 mg of trehalose, 1 mL-5 mL of thymol nanoemulsion, 10 mg-20 mg of beta-cyclodextrin and 0.8 g-1. 0 g of ethyl alcohol, and water is used as a solvent. The content of strawberry ketone, ester and norisoprene compounds in the fruits to which the regulator is applied is obviously increased, nerol and beta-ionone are detected, and the variety of terpene aroma substances is enriched; after the fruit is stored in a high-temperature and high-humidity environment for 3 days, the aroma component change of the fruit to which the regulator is applied is relatively insignificant, and the aroma of the fruit is more stable than that of a reference substance and a blank reference substance.

The present invention provides a curable resin composition containing a component (A) which is at least one selected from the group consisting of (meth) acrylic acid-modified polybutadiene and (meth) acrylic acid-modified polyisoprene, and a component (B) which contains a (meth) acrylic acid ester monomer. Also provided is a polarizing film in which an optical film is laminated on at least one surface of a polarizer with an adhesive layer interposed therebetween, the adhesive layer being a cured product layer of the curable resin composition.

Phytol (PHY) is a metabolite of plant chlorophyll, is wide in source and is a chain-like diterpenoid substance consisting of four isoprene units, and the phytol ingested by animals is subjected to oxidative metabolism in vivo, so that not only can energy be provided for the animals, but also the growth of the animals can be promoted, and the growth of the animals can be promoted. Moreover, the phytol and the phytanic acid metabolite of the phytol can also be used as signal molecules to participate in glycolipid metabolism and adipocyte differentiation regulation processes, but people cannot directly take the phytol and the phytanic acid from the nature. The effect of phytol in the generation and development of tumors still has huge unknown property. According to the research, the influence of the phytol and the derivative thereof on the growth of colon cancer, breast cancer and melanoma is detected through an in-vitro experiment CCK-8 (Cell Count Kit 8) and an in-vivo experiment such as a mouse subcutaneous tumor model, and the phytol and the derivative thereof are found to be capable of remarkably inhibiting the growth of colon cancer, breast cancer and melanoma and have no obvious toxic and side effects on heart, liver and kidney functions.

To provide a pressure-sensitive adhesive composition for a decorative sheet, which is excellent in adhesion to a low-polarity adherend, heat-resistant adhesion, heat-resistant holding power, and transparency / moldability (coating appearance after molding) in decoration of a molded article, and to provide a decorative sheet and a decorative structure.SOLUTION: The problem is solved by a pressure-sensitive adhesive composition for a decorative sheet containing a block copolymer (A) and a tackifier resin (B), the pressure-sensitive adhesive composition containing a styrene-based elastomer (a- 1) having a soft block composed of at least one of polybutadiene and polyisoprene and a hard block composed of a polymer of a vinyl aromatic compound, and the tackifier resin (B) having a softening point of 125 to 200 °C.SELECTED DRAWING: None

Disclosed herein are tire tread rubber compositions comprising a specified elastomer component, reinforcing silica filler, a combination of specified hydrocarbon resins, liquid plasticizer, and a cure package. The elastomer component includes styrene-butadiene rubber; polybutadiene; and natural rubber, polyisoprene, or a combination thereof. Also disclosed are methods for providing a tire tread having improved dry handling and wet traction performance.

The invention provides a method for preparing 3-methoxy-3-methylbutanol. Under the action of an acidic catalyst, isoprene, water and methanol undergo addition reaction, and 3-methoxy-3-methylbutanol is generated through a one-step reaction in a reactor. The reaction has the characteristics of low raw material cost, mild reaction conditions, high selectivity and high conversion rate.

The purpose of the present invention is to provide a method for producing ambrein by which ambrein can be easily and efficiently obtained.　This problem can be solved by a mutant tetraprenyl-β-curcumene cyclase in which aspartic acid that is the fourth amino acid residue of a DXDD motif is substituted by an amino acid other than aspartic acid and the seventh amino acid of a (D / N)G(T / L)(L / F / Y)(Y / F)SY motif is substituted by an amino acid other than tyrosine, said mutant tetraprenyl-β-curcumene cyclase: (a) having nine specific motifs; (b) having 40% or higher sequence identity with the amino acid sequence represented by SEQ ID NO: 1; and (c) showing an ambrein synthesis activity using 8α-hydroxypolypoda-13,17,21-triene as a substrate.

The present application relates to a kind of palladium catalytic ligand regulated azlactone retroisoprenylation method. Specifically, azlactone compound and isoprene react under the action of zero-valent palladium catalyst and monophosphine ligand, and retroisoprenylation product is obtained. A series of azlactone retroisoprenylation derivatives are obtained by simple and safe steps in the present application.

A genetically engineered microbe capable of producing isoprene from glycerol includes at least a native nucleic acid sequence encoding at least a native enzyme capable of catalyzing one or more steps of a conversion from at least a carbon source to acetyl coenzyme A (A-CoA), at least a first heterologous nucleic acid sequence encoding at least a first enzyme of a mevalonate (MVA) pathway, and at least a second heterologous nucleic acid sequence encoding at least a second enzyme capable of catalyzing at least a terpene-producing chemical reaction, wherein the at least a carbon source includes glycerol.

The present invention is related to fermentative production of isoprenoids, comprising cultivation of a suitable host cell, such as fungal host cell, particularly oleaginous host cell, in an improved two-phase culture system.

The invention relates to a strain for degrading beta-carotene, a crude enzyme solution, dioxygenase and application, and relates to the technical field of genetic engineering and microbial fermentation. The invention relates to a strain for degrading beta-carotene, the preservation name of the strain is Escherichia coli LZU-E1, and the strain is preserved in the China General Microbiological Culture Collection Center (CGMCC) with the preservation number of CGMCC No.34862. The invention further discloses a preparation method of the strain for degrading beta-carotene. The method comprises the following steps: screening a strain for efficiently degrading beta-carotene, extracting a crude enzyme solution, researching the enzymatic property of the crude enzyme solution, and mining a new dioxygenase gene for degrading beta-carotene from genome information of the strain by utilizing a molecular biology means, so that the isoprene-reduced natural perfume is efficiently obtained.

The invention relates to a method for synthesizing trans-isopentenyl substituted indolone under the catalysis of transition metal nickel. Specifically, a metal nickel catalyst (Ni (cod) 2) and tricyclohexylphosphine (PCy3) are used as ligands, C3 unsubstituted indolone is used as a nucleophilic reagent to react with isoprene, and a trans-isopentenyl substituted indolone product is obtained. And then taking the product as a reaction raw material, and carrying out nucleophilic substitution reaction on the product and halogenated alkane under an alkaline condition to obtain the 3, 3-disubstituted indolone with divergent functional groups. According to the invention, isoprene is used as a reaction precursor, a trans-isopentenyl substituted indolone product is obtained with high activity and selectivity, a nucleophilic substitution reaction is relayed, and a new strategy is provided for flexibly and conveniently introducing functional groups with different steric hindrances and electrical properties.