The invention discloses a full biodegradation plastic material, which comprises, by weight, the polylactic acid 20-40%, the long-chain branch aliphatic polyester or long-chain branch aliphatic series-aromatic copolyesters 50-60%, the chain extender 0.1-3%, the filler 1-10%, the plasticizer 5-10%, the antioxygen 0.1-1%, the lubricant 0.1-1%, the stabilizer 0.1-1% and the nucleating agent 0.1-1%. A preparation method of the full biodegradation plastic material comprises the steps of enabling all components to be mixed in a high speed mixer, feeding in a twin-screw extruder after accurate measurement by means of a measurement scale to conduct squeezing-out and prilling to obtain the full biodegradation plastic material. The full biodegradation plastic material improves mechanical property of biodegradable plastic (PBSA) products by adjusting screw combination and extruding through reaction mixing and improves suppleness and degradation rate of the polylactic acid simultaneously, the obtained full biodegradation plastic material has not only excellent biodegradation performance and aging quality, but also excellent mechanical property and blow-film processability.