The invention discloses an anti-seismic building block for house building. The anti-seismic building block comprises a device body, an anti-seismic device is fixedly installed in the device body, a rubber interlayer is fixedly installed on the outer wall of the anti-seismic device, a steel plate interlayer is fixedly installed on the outer wall of the rubber interlayer, a damping layer is fixedlyinstalled on the outer wall of the steel plate interlayer, and a protective layer is fixedly mounted on the outer wall of the damping layer. By arranging the rubber interlayer, the steel plate interlayer, the damping interlayer and the protective layer, the earthquake feeling and harm caused by an earthquake can be gradually reduced in an anti-seismic process, by arranging the anti-seismic device,vibration caused by the earthquake can be reduced, the device body is protected against damage, it is guaranteed that residents are in a safe state in the earthquake, the building block damage causedby earthquakes is avoided, the safety of the residents is improved, and the afraid of the residents in life is effectively reduced, so that the residents can live normally.