The invention proposes a plant for the production of sterile bottles by blowing from preforms (12), which has a disinfection unit (26), a heat conditioning unit, a molding unit, the disinfection unit (26) has a spraying device (36), The spraying device is equipped with nozzles (38) which, over each preform (12), direct a stream of vaporized sterilizing agent (F ) into the preform (12), said central injection axis (A2) being generally parallel to the axis (A1) of the preform (12) during processing and offset radially from the preform (12) axis (A1).