The invention discloses intelligent wireless sensing dressing capable of being used for monitoring wound surface heeling in real time. The intelligent wireless sensing dressing comprises wound surface dressing and a monitoring device, wherein the monitoring device is embedded in the wound surface dressing, is used for monitoring the temperature, the humidity, the pH value, the oxygen content, the NO (Nitrogen Oxide) concentration and microbes of the wound surface, and comprises a CPU (Central Processing Unit) control module, an input module, an output module, a Bluetooth module, sensor modules, a storage module and a power supply module; the CPU module is arranged on a flexible circuit board or an ordinary circuit board; the input module, the output module, the Bluetooth module, the sensor module, the storage module and the power supply module are interacted with the CPU control module; and the power supply module is simultaneously and electrically connected with the input module, the output module, the Bluetooth module, the storage module and various sensor modules. The intelligent wireless sensing dressing has the advantages that the wound surface information can be provided under the condition without changing the dressing; the dressing is reasonably changed according to the heeling condition of a patient; and the personalized medical care is realized, so that unnecessary waste is reduced; the pain of the patient is reduced; the wound surface heeling is accelerated; the hospital staying time of the patient is shortened; and the hospitalization expenses are reduced.