The invention belongs to the technical field of medical instruments, and discloses a sterilizing mechanism of a cotton swab used in the hematology department. The sterilizing mechanism of the cotton swabs used in the hematology department comprises a base, wherein a shell adheres to the upper surface of the base, a shell cover is inserted into the shell, a placing cylinder adheres to the inner wall of the shell, a sterilizing lamp is arranged on the inner left wall of the shell, an installation groove is formed in the left side surface of the base, a guide groove is formed in the middle of thebottom wall of the installation groove, and a guide block is slidably connected to the inside of the guide groove, and a label outlet mechanism is arranged in the installation groove. According to the sterilizing mechanism of the cotton swabs used in the hematology department, the sterilizing lamp is utilized to continuously provide ultraviolet disinfection for the cotton swabs in the shell, meanwhile, the arrangement of the swab outlet mechanism is utilized, the cotton swabs can be taken out for use, meanwhile, the swab heads of the cotton swabs can be sterilized by using sterilizing liquid,the operation is convenient, the complex operation of manually dipping and eliminating the sterilizing liquid in the prior art is simplified, the cotton swabs can be sufficiently sterilized by matching the two disinfection modes, and the use sanitation is ensured.