The invention discloses a wall-mounted air purifier based on heat regeneration and a control method of the wall-mounted air purifier. The purifier comprises a closed cabin, a flow sensor, a VOCs sensor, a both-way draught fan, an efficient renewable VOCs and formaldehyde adsorption material, a coarse effect filter, a heating body, a first temperature sensor, five air valves, a second temperature sensor and a pressure release valve. The closed cabin is divided into a left heating regeneration chamber and a right air purifying chamber. The flow sensor, the VOCs sensor, the both-way draught fan, the efficient renewable VOCs and formaldehyde adsorption material and the coarse effect filter are sequentially arranged in the air purifying chamber from top to bottom. The heating body and the first temperature sensor are arranged in the heating regeneration chamber from top to bottom. The air valves control an air flue. The second temperature sensor is arranged indoors. The pressure release valve is arranged on a heating regeneration chamber wall and penetrates the wall to communicate with an outdoor part, and during pressure releasing of the pressure release valve, indoor secondary pollution cannot be generated. A real-time and time keeping combined method is adopted for conducting ash removal on the coarse effect filter, and a timing and temperature measuring method is used for controlling the dirt drainage time duration to ensure that after dirt drainage is over, the temperature in the cabin adapts to the indoor temperature. According to the wall-mounted air purifier based on heat regeneration and the control method of the wall-mounted air purifier, the structure is simple, operation is convenient, safety and reliability are achieved, and the control method is a manner for effectively purifying the indoor air for a long term.