The invention discloses a pooling communication method between a highway electronic prepaid card and an encryption machine. The pooling communication method comprises the steps of defining a basic format of return data of the encryption machine, and defining a buffer area through the basic format; establishing a connecting pool object factory, an assembling thread and a reading thread by a server, verifying original data through the connecting pool object factory, putting the verified original data into the buffer area of the encryption machine in a message way through the assembling thread, and returning to an index of the buffer area; reading messages in the buffer area by the encryption machine, writing encrypted data according to the basic format, and transmitting the encrypted data into the buffer area according to the index; and reading the encrypted data in the buffer area by the server, transmitting the encrypted data to a card reader, sending the encrypted data to the highway electronic prepaid card by the card reader after the card reader receives the encrypted data, and calculating by the highway electronic prepaid card according to the encrypted data. According to the pooling communication method disclosed by the invention, the encryption effectiveness is increased, a system resource is prevented from being unused, and the working efficiency is increased.