The invention discloses a full automatic tooling clamp for semi-crankshaft finish machining. The tooling clamp is characterized by comprising a base, two side plates, a cover plate, two locating blocks, a floating pressing mechanism, a locating pin and a radial pressing mechanism, wherein the bottom parts of the two side plates are fixedly welded on the base, the cover plate is fixedly connected with the top parts of the two side plates through screws, and an n shape is formed by the two side blocks and the cover plate; the top of the cover plate is transversely and fixedly provided with the two locking blocks, the top surfaces of the two locking blocks are located in a same horizontal plane, a locating pin mounting hole and a crankshaft journal mounting hole which vertically penetrate through the cover plate are formed between the two locating blocks of the cover plate and the locating pin is arranged in the locating pin mounting hole; the cover plate is longitudinally provided with the radial pressing mechanism, and the floating pressing mechanism is arranged above the locating block. The full automatic unmanned processing can be realized; furthermore, each link can be detected, including the feeding and discharging in-place detection of a manipulator, work-piece clamping and loosening detection, work-piece clamping in-place request processing or discharging detection and the like.