The invention belongs to the technical field of image processing, and discloses an image processing system in orthopedic anesthesia based on optimized sedation management and regional blocking. The image processing system comprises an ultrasonic image obtaining module, an operation state detection module, a main control module, an image processing module, a three-dimensional navigation module, a storage module and a display module. Through the image processing module, a doctor is prevented from manually identifying lesion tissue, the image identifying efficiency is improved, the doctor does not need to have a high lesion identification ability, and the labor cost is reduced. Through the three-dimensional navigation module, a virtual bone image of a surgical spot of a user and a three-dimensional image of the specific location, where a surgical instrument enters, in the user body are overlaid on a real vision of the doctor, in the surgical process, real-time navigation is conducted, thesurgical operation efficiency of the doctor is greatly improved, and a surgery is more safely, accurately and efficiently implemented.