32results about How to "Reduced stress shielding" patented technology

Particular aspects provide novel devices for bone tissue engineering, comprising a metal or metal-based composite member/material comprising an interior macroporous structure in which porosity may vary from 0-90% (v), the member comprising a surface region having a surface pore size, porosity, and composition designed to encourage cell growth and adhesion thereon, to provide a device suitable for bone tissue engineering in a recipient subject. In certain aspects, the device further comprises a gradient of pore size, porosity, and material composition extending from the surface region throughout the interior of the device, wherein the gradient transition is continuous, discontinuous or seamless and the growth of cells extending from the surface region inward is promoted. Additional aspects provide a device for bone tissue engineering, comprising a metal or metal-based composite member/material comprising an interior porous structure, wherein the pore size, porosity and material composition is selected to provide a device having an optimal density and/or elastic modulus and/or compression strength for a specific recipient. Novel methods for fabricating the devices are also provided.

A motion restoring prosthesis to be interposed between the ends of two bones adjoining a mammalian appendage or spinal joint is formed of two components with the components having inner cooperating articulating surfaces and outer bone engaging surfaces. At least one of the components has an inner section made of relatively hard, stiff material defining one or the articulating surfaces and an outer section made of a softer material defining the bone engaging surface. The softer material having a hardness/stiffness characteristic compatible with the bone to reduce stress shielding and more evenly distribute the forces from the articulating surfaces to the associate bone interface.

The invention relates to a biomedical titanium-niobium-based shape memory alloy as well as a preparation method, a processing method and an application method thereof. The alloy comprises the following chemical compositions by weight percent: 28-39% of niobium, 0.35-5.5% of tin, 0.3-5.5% of aluminum, 0.5-5.5% of silicon, 0.2-5.5% of zirconium and the allowance of titanium. The alloy has the advantages of low elasticity modulus, good biocompatibility and mechanics compatibility, no toxic nickel element, good mechanical property and corrosion resisting property, excellent cold working property and low cold-working hardening ratio; the alloy can be used for cold working with large deformation such as cold rolling, cold wire drawing and the like, and the working cost is low. The titanium-niobium-based shape memory alloy is of the ideal and novel biological shape memory alloy material that replaces the TiNi shape memory alloy and can be widely used for an ultra-flexible bracket, an orthodontics dental arch wire and an orthopedics implantation instrument and the like in the fields of the medical treatment, the sports goods and the like.

This invention relates to a biodegradable implant including magnesium, wherein the magnesium contains, as impurities, (i) manganese (Mn); and (ii) one selected from the group consisting of iron (Fe), nickel (Ni) and mixtures of iron (Fe) and nickel (Ni), wherein the impurities satisfy the following condition: 0</(i)≦5, and an amount of the impurities is 1 part by weight or less but exceeding 0 parts by weight based on 100 parts by weight of the magnesium, and to a method of manufacturing the same.

The invention discloses a preparation method for a medical antibacterial titanium alloy and belongs to the technical field of biomedical material preparation. The method comprises the following stepsthat Ti power, Nb power, Zr power and Ag powder are weighed according to the mass percentages of 52-62% of Ti, 15-38% of Nb, 5-13% of Zr and 2-10% of Ag; all the powder is put into a ball milling tankfor ball milling; the powder is taken out after ball milling and dried at low temperature, and the mixed powder is obtained; the mixed powder is put into a graphite mold and then put into a dischargeplasma sintering furnace, axial pressure of 60-70 MPa is applied, sintering is carried out at the vacuum degree of 2-10 Pa, the temperature is increased to the sintering temperature of 900-1,000 DEGC, the temperature is kept for 2-5 minutes, then the vacuum is kept continuously, the temperature is lowered to the room temperature, and the Ti-Nb-Zr-Ag alloy is obtained. The prepared Ti-Nb-Zr-Ag alloy has low elastic modulus (38-49 GPa) and high strength (880-1,200 MPa) and is antibacterial.

An expandable interbody spacer includes a first endplate surface located on a first side of the spacer and adapted to contact a vertebral endplate surface of a first vertebral body, a second endplate surface located on a second, opposed, side of the spacer and adapted to contact a vertebral endplate surface of a second, opposed, vertebral body and an expansion mechanism adapted to selectively apply a distracting force between the first endplate surface and the second endplate surface, whereby actuation of the expansion mechanism causes the spacer to transition between a compressed insertion configuration to an expanded fusion configuration. The spacer also includes one or more of a deformable surface, a porosity to promote bone on-growth or through-growth, a stiffness substantially equivalent to cortical bone, and structure distributing loads through the spacer substantially without transferring the loads through higher-stiffness structures.

The invention discloses a manufacturing method of an atlas and axis titanium alloy prosthesis. The method comprises the steps of uploading CT tomography data of DICOM format of the spine medical image into the MINICS software, establishing three dimensional model data of spine to be reconstructed, implementing noise reduction by using the Geomagic software, exporting a 3D data file of step format, importing the file into the SolidWorks software, selecting the right design surfaces in the third section of the spine and the skull, establishing a prosthesis prototype between the two design surfaces, making sure the prosthesis and two design surfaces are completely fit. In order to reduce the modulus of elasticity of the prosthesis, and achieve the light weight design, the inside of the prosthesis is filled with porous grids by using SolidWorks. The porous structure on the prosthesis surface is also designed.

The invention relates to an internal fixation system and a use method thereof. The internal fixation system comprises a bone fracture plate of an inert biological material and a bone fracture screw ofone or more capable of degrading a magnesium alloy, and may further comprise an internal fixation extraction forceps in actual use. The invention also discloses a use method of the aforementioned internal fixation system. The internal fixation system and the use method have the advantages of a traditional internal fixation system, and utilize the feature that the position that the bone fracture plate is in contact with the bone fracture screw easily generates galvanic corrosion so that corrosion residual screws can be simply and quickly cut off when taking out the bone fracture plate, and screw rod parts of the remaining bone fracture screws can remain in a human body, thereby reducing the hospitalization rate and hospitalization time of patients, and improving the surgical satisfaction of the patients.

The invention discloses a manufacturing method of an individualized customized knee joint topological optimization bionic prosthesis based on 3D printing, which relates to the technical field of medical artificial joints. The problem that the manufacturing method is urgently needed to reduce prosthesis looseness or fracture around the prosthesis is solved, and the method comprises the steps: establishing and assembling a tibia model and a knee joint prosthesis model, and performing finite element analysis and topological optimization; carrying out fairing; designing a specific structure of themodel, optimally reserving an internal region by adopting a solid structure, optimally reserving an outer layer region and optimally removing the region by adopting a grid structure, and forming a gradient between the regions; introducing back an assembly state of a tibia model, performing finite element analysis, comparing with a first finite element analysis result, judging whether 3D manufacturing and application are performed or not, and performing topological optimization again if the 3D manufacturing and application cannot be performed. The prosthesis prepared by the invention reduces the problem of prosthesis looseness or prosthesis peripheral fracture, provides space for ligament stop point implantation and internal bone grafting, is light in weight, and is beneficial to bone tissue ingrowth.

The invention discloses a multi-material porous distal femur implant and a manufacturing method thereof. The implant comprises a hard gradient porous distal femur implantation trunk and soft hydrogel cartilage; the hard gradient porous distal femur implantation trunk is of a porous structure, and the outer contour includes a conical femur body and two quasi-sphere-like imitated femur ankles; the soft hydrogel cartilage includes two semi-circular-ring-shaped coverings, and the two semi-circular-ring-shaped coverings are covered with the two imitated femur ankles respectively. According to the multi-material porous distal femur implant, the bionic design that a hard material and a soft material are combined is adopted, the structural composition of the normal distal femur of a human body can be imitated to the maximum extent; by adopting a way of combining the soft material and corresponding stem cells, after being implanted, the soft material can be stimulated through tissue engineering to generate blood capillaries, so that the adaptability of the implant in the human body is improved; and moreover, by adopting a way of combining hydroxyapatite and titanium alloy, the brittleness problem of a single-material hydroxyapatite implant can be avoided.

The invention provides a paint for preparing porous materials through laser synthesizing reaction, wherein the paint comprises 20-80 wt% of NiTi shape memory powdered alloy, 2-10 wt% of high molecular polymer as binding agent and balancing TiH2 powder.

The invention discloses an orthopedic implant device which comprises an intramedullary nail main body which is of a core-shell structure, the bending strength of a main body core is improved by laminating a continuous fiber composite material, and the torsional strength of a main body shell is improved by a continuous fiber composite material which is obliquely arranged with the main body core. An expansion containing cavity is formed in a sealing cap hole of the intramedullary nail main body, meanwhile, a taking-out unit forms an expansion structure, the surface of the expansion structure is attached to or partially attached to the side wall of the expansion containing cavity, the shearing stress area is increased through the arrangement, and the requirement for the shearing strength of materials is correspondingly lowered; meanwhile, a clamping force is formed between the expansion structureand the expansion containing cavity, and the resultant force application of the clamping force avoids the phenomenon that when a taking-out unit in the prior art is applied to an intramedullary nail main body prepared from a continuous fiber composite material, a stressed part is located at a thread with low shear strength, and consequently the thread is broken and/or expanded.