14 results about "Thiolactone" patented technology

A full continuous-flow preparation method of (+)-biotin, including: subjecting a cyclic anhydride and a chiral biphenyl propylene glycol to asymmetric ring-opening reaction to produce a first intermediate, which undergoes selective reduction with a borohydride and cyclization with an inorganic mineral acid to produce (3aS, 6aR)-lactone; subjecting the (3aS, 6aR)-lactone and a sulfenylating reagent to sulfenylation to produce (3aS, 6aR)-thiolactone, which undergoes Fukuyama coupling with a zinc reagent in the presence of a palladium catalyst and elimination reaction in the presence of an inorganic mineral acid to produce an alkenyl valerate compound; subjecting the alkenyl valerate compound to reduction in the presence of a Pd / C catalyst to produce a valerate ester, which undergoes hydrolysis to produce a valeric acid salt; and subjecting the valeric acid salt to debenzylation in the presence of an inorganic mineral acid to produce the target product (+)-biotin.

This invention discloses a method for preparing hydrophobic and oleophobic photovoltaic glass, comprising the following steps: Step 1: Preparing ordinary photovoltaic glass according to conventional photovoltaic glass preparation methods; Step 2: Preparing a hydrophobic and oleophobic modified epoxy resin coating solution, wherein the hydrophobic and oleophobic modified epoxy resin coating solution comprises, by weight, 2-5 parts of thiolactone-terminated fluorinated prepolymer, 15-16 parts of 4,4'-diaminodiphenylmethane, 0.13-0.14 parts of alkaline catalyst, 25-26.5 parts of epoxy resin, and the remainder being tetrahydrofuran solvent; Step 3: Preparing the hydrophobic and oleophobic photovoltaic glass by spraying the hydrophobic and oleophobic modified epoxy resin coating solution obtained in Step 2 onto the surface of the photovoltaic glass obtained in Step 1, and after curing and drying, forming a hydrophobic and oleophobic layer on the surface of the photovoltaic glass, thereby obtaining the hydrophobic and oleophobic photovoltaic glass. The hydrophobic and oleophobic photovoltaic glass provided by this invention achieves improved hydrophobic and oleophobic properties without affecting light transmittance.

A process for preparing preferably degradable copolymers by free radical ring-opening polymerization using thionolactone monomers or thionocarbonate monomers, in the presence of a radical polymerization initiator. Also, the copolymers, which include thioester or thiocarbonate bonds, that are obtained by carrying out the process including the free radical ring-opening polymerization using thionolactone monomers or thionocarbonate monomers.

Nitric oxide precursors for providing nitric oxide are provided. The nitric oxide precursors comprise a reaction product of a thiolactone, a primary amine, and a nitrosating compound. The nitric oxide precursors are capable of decomposing to form nitric oxide.

The invention relates to a porous polymer material and a preparation method and application thereof.The preparation method comprises the steps that firstly, a compound containing sulfydryl and thiolactone is designed and synthesized, a mixed solution of the compound, a polar solvent and a surfactant serves as a continuous phase, a non-polar solvent serves as a dispersion phase, oil-in-oil type high-internal-phase emulsion is formed after emulsification, and the porous polymer material is obtained; and reacting with a polyamine compound to obtain the sulfydryl-containing porous polymer material. The prepared porous material can adsorb heavy metal ions in water and can be used in the field of water treatment.

A nitric oxide precursor for providing nitric oxide is provided. The nitric oxide precursor comprises a reaction product of a thiolactone, a primary amine, and a nitrosating compound. The nitric oxide precursor is capable of decomposing to form nitric oxide.

The invention discloses a preparation method and antibacterial application of a cationic polymer rich in guanidyl, and belongs to the field of medical polymer materials. The preparation method of the cationic polymer rich in guanidyl comprises the following steps: dissolving thiolactone acrylamide in a solvent, and adjusting the pH value to be alkaline to obtain a thiolactone acrylamide solution; and adding an amine compound into the thiolactone acrylamide solution, reacting, and dialyzing to obtain the cationic polymer rich in guanidyl, wherein the amine compound is a primary amine compound or a secondary amine compound, and the amine compound contains agmatine sulfate. According to the invention, through molecular design and synthesis condition optimization, and screening of antimicrobial performance, biocompatibility and the like, the guanidyl cationic antibacterial polymer with excellent comprehensive performance of antibacterial effect and safety is finally obtained. The guanidyl cationic polymer shows good broad-spectrum antibacterial activity and biofilm resistance activity.

The present disclosure provides thionolactones (e.g., compounds of Formula II, and tautomers and salts thereof). The thionolactones may be useful as comonomers to copolymerize with other comonomers, e.g., methacrylates (e.g., MMA) to generate copolymers, e.g., random copolymers. The copolymers may be degradable (e.g., backbone degradable). The copolymers may be useful for waste management or biodegradability.

The present invention relates to polydithioacetal copolymers, preferably degradable or biodegradable, their manufacture process by radical polymerization, their uses, the use of dithiolactones as precursor co-monomers in radical polymerization, and dithiolactones for the preparation of said copolymer or for carrying out said process. More particularly, the present invention relates to a process for preparing copolymers, preferably degradable or biodegradable, by radical polymerization, notably employing at least one dithiolactone monomer and at least one monomer comprising an ethylenic unsaturation. Figure for the abstract: Fig. 1

A nitric oxide precursor for providing nitric oxide is provided. The nitric oxide precursor comprises a reaction product of a thiolactone, a primary amine, and a nitrosated compound. The nitric oxide precursor is capable of decomposing to form nitric oxide.

The present application relates to a kind of dual dynamic key crosslinking near-infrared light response liquid crystal elastomer and its preparation method, belong to liquid crystal elastomer technical field.The liquid crystal elastomer is by liquid crystal monomer, dopamine hydrochloride monomer, chain extender and crosslinking agent under the action of triethylamine by Michael addition polymerization, obtain the main chain type liquid crystal polymer containing catechol and thiolactone side group, liquid crystal polymer is by Fe 3+ The liquid crystal elastomer with dynamic crosslinking network formed by catechol coordination interaction.The present application realizes the pre-crosslinking of liquid crystal elastomer by Fe 3+ Catechol coordination interaction realizes the pre-crosslinking of liquid crystal elastomer while introducing photo-thermal effect, and the photo-thermal effect is excellent, and can enhance the mechanical properties of liquid crystal elastomer;Thiolactone side group is fixed by ring-opening crosslinking reaction with di-functional primary amine and the single-domain structure of liquid crystal elastomer, and the programming preparation method is simple and efficient.

At least one nanoworm comprises a plurality of alkene units and a plurality of macroCTA polymer units. The macroCTA polymer units include R1 groups from reversible addition-fragmentation chain-transfer agents. In certain aspects, the R1 groups of the macroCTA polymer units are functional groups, such as a carboxylic acid, an alkyne, a pyridine, a dopamine, a thiolactone, a biotin, an azide, a peptide sequence, a sugar sequence, a protease, a glycanase, a polymer, other functional groups, and combinations thereof. In certain aspects, the macroCTA polymer units comprise quaternized amines. In certain aspects, the macroCTA polymer units comprise functionalized quaternized amines, such as an alkyl group, a carboxylic acid, an alkyne, a pyridine, a dopamine, a thiolactone, a biotin, an azide, a peptide sequence, a sugar sequence, a protease, a glycanase, a polymer, other functional groups, and combinations thereof. In certain aspects, the coating comprises the at least one nanoworm.

The invention discloses a preparation method of homocysteine thiolactone hydrochloride, which comprises the following steps: preparing a DL-homocystine crude product, preparing a DL-homocystine refined product, dissolving the DL-homocystine refined product in diluted hydrochloric acid, and carrying out electrolytic reaction by using an electrolytic bath. And collecting catholyte, adding activated carbon into the catholyte for decoloration and filtration, then performing vacuum concentration, cleaning with an ethanol solution, and drying after cleaning to obtain the DL-homocysteine thiolactone hydrochloride. After the homocystine crude product is prepared, the homocystine crude product is refined, so that the appearance chromaticity and purity of a subsequent product can be improved. According to the invention, the preparation process of the cathode material glassy carbon is optimized, so that higher total yield can be obtained when the modified glassy carbon is used as the cathode material.

The present disclosure discloses a novel method for interfacial chain-growth polymerization and an ultra-high molecular weight polymer. The present disclosure pertains to the technical field of preparing an ultra-high molecular weight polymer. The novel method for interfacial chain-growth polymerization comprising steps of: mixing a combined catalyst of an organic base and a hydrogen bond donor, an initiator, a monomer to carry out the interfacial chain-growth polymerization; wherein the monomer is selected from a lactide, a lactone, a thiolactone, a lactam, an acrylate or an olefin; the initiator is one or more selected from the group consisting of alcohol-based substances and thiol-based substances; and the hydrogen bond donor is selected from a structure represented by Formula 1 or a structure represented by Formula 2. The novel method effectively suppresses polymerization side reactions through phase separation of the polymer chains from the solvent, thereby obtaining an ultra-high molecular weight polymer. The poly(thioglycolide) of the ultra-high molecular weight polymer has good thermal and mechanical properties, and excellent barrier property, especially outstanding oxygen barrier property. Also, the poly(thioglycolide) can be recycled by solution depolymerization.