The invention discloses a slow-release moisturizing face cream and a preparation method thereof. The face cream is prepared from the following components in percentage by mass of 5-15% of polyhydric alcohol, 1-5% of fatty alcohol, 2% of polydimethylsiloxane, 1-25% of grease, 0.1-10% of a skin-care active ingredient, 0.5-2% of an emulsifier, 0.2-2.8% of a pH regulator, 0.2-1.5% of an antioxidant, 0.2-2% of a thickening agent and the balance of water. The preparation method comprises the following steps of S1, weighing the raw materials; S2, mixing the grease, the fatty alcohol and the emulsifier, mixing a mixture with 30% of the total amount of the skin-care active ingredient, and carrying out heating and stirring until a mixture is dissolved to obtain an oil phase; S3, mixing the polyhydric alcohol, the pH regulator, the antioxidant, the thickening agent and the water, mixing a mixture with 30% of the total amount of the skin-care active ingredient, carrying out stirring until a mixture is completely dispersed, heating to 85 DEG C, and cooling to 80 DEG C after 5 minutes to obtain a water phase; S4, pouring the water phase into the oil phase, carrying out homogenizing, and cooling to 65 DEG C to obtain a dispersed phase; S5, adding silicone oil, and carrying out homogenizing to obtain a fourth mixture; and S6, cooling the fourth mixture to 45 DEG C, adding the remaining skin-care active ingredient, and cooling to 25 DEG C to obtain the face cream.