The invention discloses a novel tunnel segment structure and a stress monitoring device thereof, and relates to the technical field of tunnel laying and tunnel and underground engineering. According to the key points of the technical scheme, the novel tunnel segment structure includes novel lining segments capable of being spliced into unit tubes, sealing gaskets and pressure sensors, wherein thesealing gaskets and the pressure sensors are arranged at the junctions of the segments. The segments are in a cross shape, grooves and convex strips are arranged at the side edges of the segments alternatively and the segments are connected through the grooves and the convex strips in a joggle-joint mode to form a tunnel. The side walls of the segments are covered with rubber asphalt waterproof coating, and vulcanized ethylene-propylene rubber elastic sealing gaskets are arranged at the joints of the segments. The pressure sensors are arranged above the convex strips. Compared with the prior art, the sliding friction between the segments is increased through the cross-shaped segments, the pipeline structure is more stable, and the joggle-joint structure simplifies the construction process;meanwhile, a pressure monitoring device is additionally arranged for monitoring and recording the pressure subjected by the segments in real time for carrying out risk prevention, and further research is facilitated; and in addition, a waterproof system has certain reference value for the problem of water seepage.