The invention provides an antenna assembly which comprises a base plate, a ground plane, a feed-in portion, a first radiation portion, a second radiation portion and a third radiation portion. The ground plane is arranged on the top surface of the base plate, the antenna assembly can be grounded by the aid of the ground plane, the peripheral edge of the ground plane is hollowed out to form the first radiation portion, the second radiation portion and the third radiation portion respectively, the feed-in portion comprises a plurality of feed-in points, the feed-in points are respectively arranged on the first radiation portion, the second radiation portion and the third radiation portion, the first radiation portion is divided into a first radiation section and a second radiation section, the first radiation section is used for transmitting and receiving wireless signals in first frequency bands, the second radiation section is used for transmitting and receiving wireless signals in second frequency bands, the second radiation portion is used for transmitting and receiving wireless signals in third frequency bands, and the third radiation portion is used for transmitting and receiving wireless signals with fourth center frequencies, so that a plurality of slot antennas can be formed. The invention further provides a wireless communication device with the antenna assembly.