Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

46 results about "Anagen cycle" patented technology

The hair cycle consists of three different stages: anagen, catagen, and telogen. Hair on the body, including facial hair, are at their own phase of growth. Topical solutions like minoxidil or peppermint essential oil are known to force hair into the anagen phase.

Composition for hair, and hair growth liquid

The invention discloses a hair growth composition, wherein fullerene is dissolved in an acceptable external application carrier such as grease, and then the fullerene and other components are compounded through solubilizing or emulsifying to form the composition beneficial for hair and scalp. According to the present invention, the composition can achieve the long hair growth period of mice, shorten the hair rest period of mice, make hair lush, dense and black, significantly increase the number of hair follicles, and effectively promote the secretion of the endothelial growth factors of hair;and the composition is suitable for various problems of alopecia, hair loss, damage on hair and the like, can solve the problems of people with alopecia and hair loss, can provide effects of hair fixation, hair growth, hair development and the like within a short time, and has wide application prospect.
Owner:BEIJING FUNAKANG BIOTECH CO LTD +1

Hair-care composition containing efficient anti-hair-loss compound agent

ActiveCN103462844AReturn to normal ratioRestore hair loss speedCosmetic preparationsHair cosmeticsSugar amineRest period
The invention relates to a hair-care composition containing an efficient anti-hair-loss compound agent. The hair-care composition comprises long-chain alcohol, a cationic surface active agent, a thickening agent, essence, a preservative, a chelating agent, water and an anti-hair-loss compound active matter, wherein the anti-hair-loss compound active matter accounts for 0.1 to 10 percent of weight of the composition and is a composition of hydrolyzed soy protein, amino acid, amino sugar, vitamin B complex, zinc salt, ginseng essence, May burdock root essence, organic silicon and polyquaternium. By virtue of the hair-care composition, the hair growth can be promoted, the ratio of a growing period to a resting period of hair is improved, forming of healthy scalp and healthy hair is promoted, and the hair loss speed of a hair loss patient is returned to be normal.
Owner:LAFANG CHINA CO LTD

Biologic polysaccharide having effects of promoting hair generation, developing hair and preventing hair loss and application of biologic polysaccharide

The invention relates to biologic polysaccharide having effects of promoting hair generation, developing hair and preventing hair loss and an application of the biologic polysaccharide. Particularly,beta-glucan, particularly beta-glucan having natural solubility, high molecular weight and high viscosity (such as schizophyllum commune beta-glucan) can effectively promote hair development and / or prevent hair loss. Experiment indicates that the beta-glucan can obviously promote hair follicle in interruptio to enter the growth period, so that the hair follicle can be in the growth period for a long time, hair can be promoted to be regenerate and grow, the hair loss can be prevented, the hair can be developed, and the biologic polysaccharide has the efficacy of removing and preventing dandruffand relieving itching.
Owner:ZHEJIANG GLLION BIOTECH CO LTD

Keratinocyte culture and uses thereof

The present invention relates to the treatment of skin defects by organotypically-cultured autologous keratinocytes isolated from the outer root sheath of anagen or growing hair. Methods for primary, as well as subsequent organotypic cultures (i.e., epidermal equivalents) in fully-defined media supplemented by autologous human serum and substances isolated form blood components, with minimal allogeneic biological supplements, are disclosed herein. Techniques to prepare epidermal equivalents for transplantation by use of a biocompatible glue are also disclosed herein.
Owner:SMITH & NEPHEW INC

Compound plant anti-hair loss hair growth lotion

The invention discloses a compound plant anti-hair loss hair growth lotion. The compound plant anti-hair loss hair growth lotion includes the following components in percentages by mass: 1-5% of cacumen platycladi extract, 1-5% of camellia seed cake extract, 1-5% of ginger root extract, 1-5% of ginseng root extract, 1-5% of fructus forsythiae extract, 1-5% of radix polygoni multiflori extract, 0-0.05% of caffeine, 0.1-0.4% of an antibacterial agent, 0.1-0.5% of a moisturizer, and the balance of water. The compound plant anti-hair loss hair growth lotion provided by the invention takes hair follicle stem cells as a target, and induces the expression of multiple growth factors, thereby regulating the proliferation and differentiation of the hair follicle stem cells, improving the supply of blood to scalp, and inducing hair follicles during dormancy to return to an active growth period; and the lotion can effectively end abnormal hair loss and promote hair regeneration.
Owner:广州比力福生物科技有限公司

Hair-blacking liquid and preparation method thereof

The invention discloses a hair-blacking liquid and a preparation method thereof, and belongs to the technical field of cosmetics. The hair-blacking liquid comprises a substrate and a traditional Chinese medicine extract, wherein the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 20-40 parts of a salvia miltiorrhiza extract, 10-20 parts of a prepared radix polygoni multiflori extract, 10-20 parts of a radix rehmanniae recen extract, 30-50 parts of a cacumen biotae extract and 10-20 parts of a peach branch extract. The hair-blacking liquid disclosed by the invention takes pure Chinese herbal medicines as active ingredients, does not contain chemical dyeing substances, and does not cause allergy of chemical hair dyeing substances. The hair-blacking liquid disclosed by the invention is an external product for skin, does not need to be orally taken, and does not generate liver and kidney toxicity caused by long-term taking of Chinese herbal medicines. According to the hair-blacking liquid, the hair-blacking traditional Chinese medicine extracts can effectively activate the enzyme activity of tyrosinase, and melanin in new hair roots is remarkably improved.
Owner:广州莎莎化妆品制造有限公司

Compound external preparation for preventing and treating alopecia and promoting hair growth

The invention provides a compound external preparation for preventing and treating alopecia and promoting hair growth. The compound external preparation comprises the following specific components andformula weight proportions: every 100 ml of a solvent contains 1 to 50 g of metformin, 0.1 to 10 mg of finasteride, 0.1 to 50 g of minoxidil, 0.1 to 50 mg of vitamin B1 and 0.1 to 50 mg of vitamin B6; and the solvent is water or ethanol. Compared with single minoxidil, metformin, vitamins B1+B6 or combination of two drugs (combination of oral administration of the finasteride and external application of the minoxidil, combination of the minoxidil and the vitamin B1), the compound external preparation has the advantages that the hair follicle stem cells can be activated, and more hair folliclecells enter the growth period after the rest period is ended; new hair follicles in the growing period can be longer, and hair papillae are larger in size; and the component medicines in a formula can achieve a synergistic effect, and the compound external preparation has remarkable effects in the aspects of treating the alopecia and promoting the hair growth.
Owner:陈学东

Anti-alopecia hair-growing composition and application

The invention relates to an anti-alopecia hair-growing composition and application. The anti-alopecia hair-growing composition comprises raw material ingredients: hydrolyzed feather fan legumin, a yeast extract, a licorice root extract, a cacumen platycladi extract and hydrolyzed sericin. The anti-alopecia hair-growing composition disclosed by the invention can be used for providing essential micro-element nutrients for various stages of hair growth, shortening a process of hair entering a growth stage from a resting stage, meanwhile, retarding conversion from the growth stage to a regressivestage, effectively repairing injuries of scalp hair follicles, promoting growth of the hair, nourishing and fixing the hair and preventing alopecia. The anti-alopecia hair-growing composition has an obvious effect on alopecia caused by various reasons and has the characteristics of high effect taking speed, extensive applicable people and moderate action.
Owner:上海科植倍信日化科技有限公司

Method for screening a substance having promoting activity on hair growth

A method for screening a substance having promoting activity on hair growth, which comprises the steps of bringing hair follicles in telogen into contact with a test substance, and judging that the substance tested is positive when the hair follicles in telogen are led to in anagen by the substance tested, wherein the judgment is carried out by detecting expression of Hacl-1 in the hair follicles.
Owner:SUMITOMO ELECTRIC IND LTD

Hair Growth Stimulants and the Manufacturing Method Thereof

InactiveUS20080260867A1Maximize hair loss prevention hairMaximize hair hair growth effectAntibacterial agentsCosmetic preparationsHair rootsSide effect
A hair growth stimulant having excellent hair growth stimulation and hair growth effects without any side effects, which contains a carbonized pine cone. The inventive hair growth stimulant has an excellent hair growth stimulation effect without causing any side effects or toxicity to the human body, while it can stimulate hair roots to greatly influence the growth of hair so as to prevent hair loss and white hair. Also, it can be provided in the form of creams or ointments having an excellent effect on hair growth stimulation, and thus can considerably shorten a treatment period. It can keep the anagen-stage hair by increasing the blood flow of the scalp, and it consists of a vegetable preparation, and so has no side effects to the human body. In addition, it can be used through smooth application to a head, and thus is easy to use.
Owner:NAM JONG HYUN

Method for extracting exosome derived from human hair follicle dermal papilla cells

PendingCN109852578AHelp regulate growthHelp regulate developmentMicrobiological testing/measurementArtificial cell constructsGrowth phaseCD63
The invention belongs to the technical field of cell secretion extraction, and discloses a method for extracting exosome derived from human hair follicle dermal papilla cells (DPC-Exos). The method isas below: identifying DPC-Exos by controlled resistance pulse sensing (TRPS) analysis, electron microscopy and Western Blot; and adding the DPC-Exos to a culture medium of human hair follicle outer root sheath cells (ORSCs) cultured in vitro. The DPC-Exos are identified to be about 105 nm in diameter and expressing tumor susceptibility gene (TSG) 101, differentiation cluster (CD) 9 and CD63; DPC-Exos promote proliferation and migration of human ORSCs, and mRNA and protein levels of beta-catenin and Sonichedgehog (Shh) in ORSCs are detected to be up-regulated after treatment; transdermal injection of DPC-Exos accelerates an HF growth phase of mice and delays the occurrence of regression. Immunohistochemical analysis shows that the expression levels of beta-catenin and Shh are up-regulatedin the hair follicles of an experimental group. DPC-Exos help regulate the growth and growth cycle of the HF and provide a new potential for the treatment of clinical hair loss.
Owner:ZHEJIANG UNIV

Pet bath foam with hair thickening function

The invention discloses pet bath foam with a hair thickening function. The pet bath foam with the hair thickening function is mainly prepared from a polygonum multiflorum root extract, a rubus fruticosus leaf extract, and a morus nigra fruit extract. Through the adequate synergism of contained effective ingredients, the trichotrophy can be increased, the skin blood circulation and immunity are improved, the hair follicle keratin formative cell apoptosis and retrogression in a growing period are reduced, the hair growth and development are promoted, the hair follicle growth is promoted, and thehair growing period is prolonged, thereby the good action of thickening hairs is achieved.
Owner:广东创美抗衰老研究有限公司

Exosome complex liquid for treating alopecia and preparation method thereof

The invention discloses an exosome complex liquid for treating alopecia and a preparation method thereof. The exosome complex liquid comprises the following components in percentage by weight: 20%-30% of an adipose tissue-derived stromal cell exosome solution, 8%-12% of a fibroblast extracellular matrix solution, 1%-3% of a cacumen platycladi extract, 2%-4% of a polygonum multiflorum extract and the balance of normal saline. The adipose-derived mesenchymal stem cell exosome, the fibroblast extracellular matrix and the three-type collagen in the exosome composite liquid can provide nutrient substances for hair follicle cells, meanwhile, can stimulate differentiation of hair follicle stem cells, increase the number of hair follicles, stimulate hair follicles in a resting period to be converted into a growing period, and improve the hair follicle growth period. And a cacumen platycladi extract, a radix polygoni multiflori extract, amino acid and multivitamin components which are used for promoting blood circulation, resisting inflammation, removing fat and regulating immunity are supplemented, so that formation and circulation of blood vessels around hair follicles are promoted, and better hair strengthening and growing effects are achieved.
Owner:诺赛联合(北京)生物医学科技有限公司 +1

Preparation for preventing hair loss and growing hair

The invention relates to the field of hair care and recuperation, in particular to an anti-hair loss and hair growth preparation. According to mass percentage, the preparation includes 0.05-5% of dihydrosphinganine. Through testing, the present invention can transform the hair from the terminal growth phase to the initial growth phase within 8 weeks, improve the health of the scalp by balancing the microbial community, enhance the regenerative ability of the scalp, and balance the hair growth cycle by inhibiting 5-α-reductase. Maintains hair in anagen phase to prevent hair loss.
Owner:王玉艳

Application of N-(4-chloro-2,5-dimethoxyphenyl)-5-isopropyl-2-methoxybenzenesulfonamide in promotion of hair growth

The invention discloses an application of N-(4-chloro-2,5-dimethoxyphenyl)-5-isopropyl-2-methoxybenzenesulfonamide in preparation of composition for promoting hair growth. The N-(4-chloro-2,5-dimethoxyphenyl)-5-isopropyl-2-methoxybenzenesulfonamide is capable of promoting hair follicles to transform from a resting stage to a growing stage, has effects of starting and remarkably promoting hair growth, is quick in response and remarkable in effect, can be used for preparing medicines or cosmetics for treating alopecia or promoting hair growth, and has wide application prospect and value.
Owner:EAST CHINA NORMAL UNIVERSITY

Composition For Preventing Hair Loss Or Promoting Hair Regrowth

PendingUS20210268009A1Preventing alopeciaImprove hair growthOrganic active ingredientsCosmetic preparationsAnagen cycleHair Papilla
The present disclosure relates to a composition for preventing alopecia and accelerating hair growth, including an ingredient inducing new development of hair or accelerating hair growth. The composition for preventing alopecia and accelerating hair growth reduces a period of transition from a telogen stage to an anagen stage in the hair growth cycle to accelerate hair growth and to delay a transition to a catagen stage, and thus provides excellent effects of preventing alopecia and accelerating hair growth. In addition, the composition is safe to the human body, causes no side effect and provides excellent effects of accelerating proliferation of dermal papilla cells and enhancing hair elasticity.
Owner:LG HOUSEHOLD & HEALTH CARE LTD

Composition with functions of delaying senescence and prompting hair growth and application thereof

The invention belongs to the field of healthcare food, and relates to a composition with the functions of delaying senescence and prompting hair growth and application thereof. The composition is prepared from radix astragali, radix angelica sinensis, radix polygonum multiflorum preparata, herba ecliptae, fructus mori and the like. The composition can solve the problems of lusterless complexions, qi deficiency, scant hair, lusterless hair and the like in various ways on multiple levels, and achieves the effects of delaying senescence and nourishing and caring hair. On the basis, by adding sea cucumber polypeptide powder, the antioxidant activity of the sea cucumber polypeptide powder and the composition can be further significantly improved, senescence can be delayed, hair follicles can enter the growing period fast, the number of hair follicles can be increased, and thus the effect of promoting hair growth can be achieved. The composition can be applied to healthcare food for delaying senescence and prompting hair growth, is wide in application range and has good economic and social effects.
Owner:INFINITUS (CHINA) CO LTD

Freeze-dried powder preparation for hair regeneration and healing as well as preparation method and application thereof

The invention relates to a freeze-dried powder preparation for hair regeneration and healing as well as a preparation method and application thereof. The preparation method comprises a step 1 that an available healthy umbilical cord is taken and cleaned, Wharton's jelly is stripped and cut into small pieces, the small pieces are spread in a culture container, a culture solution is added, the culture container is placed in an incubator for culture, and P0-generation cells are collected after culture is conducted for 13-15 days; a step 2 that the P0-generation cells are put into an incubator according to the density of 1.4 million cells per bottle, and subjected to subculture for 3 days; and a step 3 that culture is terminated when the the fusion degree of the cells reaches 90% during culturing the P0 generation cells, a supernate liquid is collected and continuously freeze-dried in a freeze dryer for 50-54 hours to obtain the freeze-dried powder. The stem cell supernate contains various growth factors, so that hair follicles can be induced to be converted into a growth period from a resting period, hair growth can be promoted, and the problem of alopecia can be fundamentally solved.
Owner:郑州市和沐生物科技有限公司

Glucohexaose and preparation method and application thereof, and hair regeneration preparation

The invention relates to the technical field of skin hair regeneration, in particular to glucohexaose and a preparation method and application thereof, and a hair regeneration preparation. The molecular structure of the glucohexaose is Man-Man-Man-Man-Glc-Glc. The gulcohexaose can specifically stimulate local macrophages to release a cytokine network mainly comprising CCL5 chemotactic factors, recruit lymphocytes mainly comprising regulatory T cells, induce immune cascade reaction, regulate immune microenvironment, activate rapid proliferation and differentiation of hair follicle stem cells at hair follicle carina and at the lower end of the carina, remarkably promote periodic regeneration of hair follicles and accelerate the process of driving the hair follicles to enter a growth period from a resting period, so as to achieve the effect of treating alopecia.
Owner:UNIVERSITY OF MACAU

Novel application of L-fucose

The invention relates to the field of medicines, and relates to a novel application of L-fucose, in particular to an application of L-fucose in preparation of products with hair loss preventing and hair growing effects. In-vitro experiments find that L-fucose can significantly up-regulate expression (p is smaller than 0.001) of a beta-catenin gene, an IGF-1 gene, a KGF-2 gene and VEGF gene and promote expression (p is smaller than 0.001) of an MMP-2 gene and an MMP-9 gene, and is helpful for inducing or maintaining hair follicle growth period and promoting hair follicle growth and dermal papilla extracellular matrix remodeling; and meanwhile, the expression (p is smaller than 0.001) of the anti-apoptosis gene bcl-2 is remarkably up-regulated, and the ratio (p is smaller than 0.005) of Bax / Bcl-2 is down-regulated, so that the apoptosis of dermal papilla cells is inhibited. The result shows that the L-fucose has good hair loss preventing and hair growing effects.
Owner:INFINITUS (CHINA) CO LTD

Method for preventing hair loss

Methods and compositions useful in the prevention and treatment of hair loss. In some embodiments, compositions are applied to hair follicles to inhibit the transition of growth phases. In some embodiments, the composition is a myosin light chain kinase (MLCK) inhibitor alone, or in conjunction with other components. In some embodiments, methods are disclosed for identifying and / or selecting compositions for use in methods of preventing or treating hair loss.
Owner:MT SINAI SCHOOL OF MEDICINE

Preparation method of artificial skin by taking VEGF165 gene modified hair follicle stem cells as seed cells

The invention relates to a preparation method of artificial skin by taking VEGF165 gene modified hair follicle stem cells as seed cells. The preparation method comprises following step: 1) hair follicle stem cells, which possess excellent cellular morphology and are in growing period, are collected; 2) the collected hair follicle stem cells are purified; 3) the hair follicle stem cells are identified; 4) lentivirus are packaged; 5) the hair follicle stem cells are infected by lentivirus; 6) gelatin sponge three-dimensional tissue scaffolds are prepared; 7) the gelatin sponge three-dimensional tissue scaffolds which are preserved at a temperature of 4 DEG C are taken, and the modified hair follicle stem cells are inoculated in the gelatin sponge three-dimensional tissue scaffolds or on the surfaces of the gelatin sponge three-dimensional tissue scaffolds by injection so as to obtain the artificial skin. According to the preparation method, the VEGF165 gene modified hair follicle stem cells are taken as the seed cells, rapid and large-scaled amplification of the hair follicle stem cells can be realized by in vitro culture, resources of the hair follicle stem cells are quite abundant, and the hair follicle stem cells are capable of reducing immunological rejection. In addition, the hair follicle stem cells are transfected and modified by VEGF165 gene, so that novel engineering blood vessel systems with expansion and contraction functions can be formed, and problems of easily caused artificial skin necrosis in transplanting and low survival rate are solved perfectly.
Owner:HANGZHOU CITY XIAOSHAN DISTRICT TRADITIONAL CHINESE MEDICAL HOSPITAL

A kind of traditional Chinese medicine anti-hair loss composition for women

The invention discloses a traditional Chinese medicinal anti-hair loss and hair growth liquid composition for women. The traditional Chinese medicinal anti-hair loss and hair growth liquid composition is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 150-170 parts of cortex lycii radicis, 120-140 parts of notopterygium, 180-200 parts of fructus crataegi cuneatae, 100-120 parts of asarum roots, 160-180 parts of ajuga multiflora, 180-200 parts of sanguisorba officinalis, 170-190 parts of rice bran and 150-170 parts of pu'er tea, wherein the components are mixed by using 70% ethyl alcohol at the ratio of traditional Chinese medicines to the ethyl alcohol of 1:6, and are soaked at a room temperature for 7d; and a soak solution is filtered through a 200-mesh stainless steel screen and then mixed to prepare a traditional Chinese medicinal anti-hair and loss hair growth liquid for women. According to the traditional Chinese medicinal anti-hair loss and hair growth liquid for women, excessive secretion of FGF5 of follicle cells is blocked through inhibiting FGF5 gene expression of the follicle cells, combination with a follicular papillary receptor is controlled, the hair follicle growth period is prolonged, the normal growth state of hair is restored and hair loss can be quickly stopped. Meanwhile, the problems of pruritus capitis and too much hair oil are solved, and the traditional Chinese medicinal anti-hair loss and hair growth liquid composition has the hair growth and hair-blacking efficacies.
Owner:广州国草夏方生物科技有限公司

R-spondin agonist-mediated hair growth

Cosmetic skin and hair care compositions for enhancing the growth and appearance of mammalian hair in an individual are provided, which compositions comprise a dose of an R-spondin agonist effective to promote anagen phase of the hair cycle.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV +1

Preparation method of organic composite trace elements suitable for fox growth period

The invention relates to a preparation method of organic composite trace elements suitable for a fox growth period, and belongs to the field of feed processing in the animal husbandry. The organic composite trace elements are prepared from the following raw materials in percentage by weight: 0.5-3.0% of basic copper chloride, 2.0-10.0% of manganese sulfate, 5.0-12.0% of zinc sulfate, 7.0-15.0% ofamino acid zinc, 30.0-40.0% of glycine iron, 1.0-10.0% of ultramicro calcium iodate, 0.5-5.0% of ultramicro sodium selenite, 0.5-4.0% of ultramicro cobalt chloride and 25.0-40.0% of medical stones. The situation that fur loses gloss or hair is in disorder cannot occur, and the phenomenon of fur alopecia areata cannot occur.
Owner:江苏蜀星饲料科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products