33 results about "Anti aggregation" patented technology

The present invention is directed to compounds, compositions, and methods useful for delivering polynucleotides or other cell-impermeable molecules to mammalian cells. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery vehicles. The use of multiple reversible linkages connecting component parts provides for physiologically responsive activity modulation.

The invention relates to a cervical exfoliated cell preservative liquid, the preservative liquid comprises the following components with the contents (by weight): 20 percent to 50 percent of alcohols; 15 percent to 50 percent of anti-aggregation reagent; 5 percent to 10 percent of buffer solution; 1 percent to 20 percent of ion strength maintaining reagent; 0.01 percent to 0.5 percent of anti-microbial reagent; 0.1 to 5 percent of mucus dissolving reagent; and 0 to 0.5 percent of cleaning agent. Compared with the prior art, the preservative liquid can not only lead cells to maintain the shape in an in vitro liquid suspension environment, minimize the protein precipitation, dissolve larger protein substances, such as blood and mucus, and reduce the cell aggregation, but can also selectively eliminate or reduce red cells, effectively kill microbes, prevent the activity of reverse transcriptase and retain the integrity of nucleic acids and proteins for facilitating the later analysis; in addition, the preservative liquid can greatly reduce the costs of consumptive materials for the TCT detection, improve the sensitivity and the specificity of the cervical cancer screening and accelerate the promotion and the popularization of the TCT technology in a medical system.

The present invention is directed to membrane active polymers useful for cellular delivery of compounds. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery conjugates. The use of reversible modification provides for physiologically responsive activity modulation.

The present invention is directed compounds for reversibly modification of biologically active molecules. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery conjugates. The use of reversible modification provides for physiologically responsive activity modulation.

The invention discloses a composite hydrate inhibitor and application thereof. The provided composite hydrate inhibitor comprises a copolymer and an anti-aggregation agent; the copolymer is selected from at least one of the following substances: poly (N-vinyl pyrrolidone-2-vinyl pyridine) and poly (N-vinyl caprolactam-2-vinyl pyridine); and the anti-aggregation agent is a quaternary ammonium saltcompound. When the series of copolymer and the anti-aggregation agent are interacted, the composite hydrate inhibitor has good hydrate generation inhibiting performance. The hydrate inhibitor is in aliquid state, and can be used in the range that the water content is 10 to 80 weight percent, the pressure is 1.5 to 70MPa and the temperature is 20 DEG C below zero to 25 DEG C. The hydrate inhibitor cannot be limited by super-cooling degree, and is suitable for oil and water coexistence or oil-gas field and crude oil recovery; and particularly under the condition of high water content, the hydrate nucleation and aggregation inhibiting effects of the inhibitor can be fully exerted. The inhibitor has the advantages of high efficiency, economical efficiency, low dose and good biodegradability,and has good application prospect.

A non-food anti-microbial-adhesion and aggregation composition comprising a suitable carrier and an effective amount of an adhesion inhibitory fraction isolated from juice from berries of the Vaccinium plant genus. In an embodiment the anti-aggregation and adhesion fraction is isolated from cranberry juice. It is characterized as being polymeric and having a molecular weight ≧14,000; an elemental analysis of carbon 43-51%, hydrogen 4-5%, no nitrogen, no sulfur and no chlorine; a nuclear magnetic resonance (NMR) line spectrum as set forth in FIGS. 2A and 2B; and an ultraviolet spectrum with an absorption peak at 280 nm in neutral or acidic pH solution which is absent in alkali solutions. This fraction exhibits adhesion inhibitory activity against P fimbriated bacteria, oral bacteria and Helicobacter pylori.

The invention discloses a white and interference-color matte flaky core-covered pigment and a preparation method thereof and relates to the field of pearlescent pigments. A base material with the grain diameter D50<=5 micrometers is coated with white metallic oxide to form a coating layer. According to the method, the base material and water are mixed to form suspension liquid, a crystal grain modifier is put in the suspension liquid, a metallic oxide crystal type transforming agent is added into the suspension liquid, the pH value is regulated, a saline solution is added dropwise into the suspension liquid, the pH value of the suspension liquid is kept stable at the same time, stirring is continued after adding is over, the pH value of the solution is regulated, an anti-aggregation agent is added, and suction filtration, drying, calcining and cooling are performed on the solution after adding is over. Compared with the prior art, the pigment prepared through the method is small in grain diameter, very fine and smooth, quite obvious in skin effect, high in covering force, good in ultraviolet absorption effect, low in luster, remarkable in matte effect and capable of being widely applied to cosmetics, sun cream, pigment toning and other industries.

The invention discloses a methanol gasoline multipurpose additive and application thereof. The methanol gasoline multipurpose additive comprises the components of isobutanol, isoamylol, acetone, dimethylbenzene, tertiary butanol, methyl tertiary butyl ether, cerium nitrate, 2, 4- dimethyl-6- tert-butyl phenol, 102 TB corrosion inhibitor and dcyclopentadiene iron. According to the invention, raw materials can be obtained easily, the processing is simple, the price is low, and the methanol gasoline multipurpose additive has good anti-detonating quality, vaporability and stability; the pollution is low after the combustion, so that the environmental protection is facilitated; the antioxidant component in the methanol gasoline multipurpose additive can prolong oxidation and dispersion time for sediment particles, so as to have an anti-aggregation raw rubber stabilizing effect on oil product olefins; the methanol gasoline multipurpose additive can prevent a filter and a nozzle from being polluted and blocked; and all components work together to improve the safety of methanol gasoline.

The invention discloses a method for preparing anti-aggregation modified nano calcium carbonate. The method comprises the following steps: (1) treating a calcium hydroxide solution; (2) performing carbonization treatment; (3) performing modification and suspension treatment; and (4) preparing anti-aggregation nano calcium carbonate. By adopting the method for preparing anti-aggregation modified nano calcium carbonate, due to reasonable process designing, the prepared nano calcium carbonate has excellent anti-aggregation performance, and the modified nano calcium carbonate is high in activity,good in size stability, excellent in performance and wide in market prospect.

The present invention relates to a compound hydrate anti-aggregation agent composition and uses thereof. A purpose of the present invention is mainly to solve the problem of easy environment pollution, poor aggregation resistance and high consumption in the prior art. The technical scheme of the present invention comprises a compound hydrate anti-aggregation agent composition and uses thereof, wherein an oil-water emulsifier, a hydrate particle anti-aggregation agent, a hydrate particle dispersant and a synergist are compounded according to a mass ratio of 0.1-5:0.1-10:0.1-10:0.1-10 to obtain the compound hydrate anti-aggregation agent composition. With the technical scheme of the present invention, the problem in the prior art is well solved. The compound hydrate anti-aggregation agent composition of the present invention can be used for oil and gas transportation.

Compositions and methods for repelling coleopterans. The compositions contain a substrate and an anti-aggregation pheremone intermixed within the substrate. The pheremone may be verbenone, methyl salycylate, wintergreen oil, or combinations thereof.

The invention discloses a method for dendroctonus armandi disorientation control by pheromones. The method includes the steps: dividing an armandi distribution area into an affected area, an unaffected area and an armandi-free distribution area in an emergence period of dendroctonus armandi; preparing host plant volatiles and dendroctonus armandi aggregation pheromones into attractants; suspendinga slow-release bottle with the attractants in the armandi-free distribution area; preparing anti-aggregation substances by taking anti-aggregation pheromones and organic matter liquid without attracting and avoiding functions for the dendroctonus armandi as solvents. By combined use of the aggregation pheromones and the anti-aggregation pheromones, the efficiency of the dendroctonus armandi harming healthy armandi is effectively reduced, and the problem of difficulty in field control of the dendroctonus armandi in the emergence period is solved. By comprehensively using three identified aggregation pheromone substances of the dendroctonus armandi, the efficiency of trapping and attracting the dendroctonus armandi is improved, and the dendroctonus armandi is disorientated.

The invention relates to an acellular pertussis vaccine, which contains a PT antigen and an FHA antigen in the supernatant part of a bordetella pertussis liquid culture and a PRN antigen in the thallus part of the bordetella pertussis liquid culture. Specifically, the PT antigen and the FHA antigen adopt hydrogen peroxide as the detoxifier, take glycerin as the anti-aggregation agent, and employ urea as the protective agent to conduct detoxification. The detoxified pertussis stock solution has good immunogenicity, is free of residual substances harmful to the human body, and has good immunogenicity and a broader spectrum of antigenicity. The invention also relates to a preparation method of the acellular pertussis vaccine, and a preparation method of a combined vaccine containing the acellular pertussis vaccine.