The invention relates to the technical field of printing machines, in particular to a combined printing machine. The combined printing machine comprises an unwinding unit, a paper feeding unit, an offset print printing unit, an offset print ink unit, a die cutting unit, a waste discharging unit and a rolling unit. The combined printing machine is suitable for printing adhesive stickers, coated paper, paperboards, aluminum foils, plastic films and other substrates. The machine adopts a unit type module combination manner and can be used for 4-8 color printing. Each color set can select any oneprinting manner from glue printing, flexible printing, silk printing and cold ironing. The overall machine adopts shaft-free transmission, an automatic registering system and a pre-registering systemare allocated, the registering accuracy at the high speed (150 m / min) is guaranteed, the rejection rate is low, and the combined printing machine is ideal equipment for printing various high-middle grade daily use chemical products, wine labels, medicine labels, packaging boxes, self-adhesive labels and the like.