This invention discloses a method, device, and storage medium for predicting the risk of diabetes in patients with
periodontal disease, relating to the field of smart healthcare technology. The method includes: acquiring biological samples from patients with
periodontal disease; detecting the expression levels of core
mediator proteins in the biological samples, including C1S, PSAP, and CFP; acquiring clinical
covariate data from patients with
periodontal disease; inputting the expression levels of the core
mediator proteins and the clinical
covariate data into a pre-trained
diabetes risk prediction model to obtain a prediction of the risk of developing diabetes in patients with periodontal
disease within a predetermined time window; wherein, the
diabetes risk prediction model is based on the XGBoost
algorithm, using the expression levels of the core
mediator proteins and the clinical
covariate data as input features, and using the outcome of diabetes as a
label for training. This invention provides a solution that can systematically elucidate the causal relationship between periodontal
disease and diabetes, achieving high-precision prediction of the
future risk of developing diabetes in patients with periodontal
disease.