5 results about "Eyes irritation" patented technology

The present application relates to an ophthalmic preparation and use thereof. Specifically, the present application relates to an ophthalmic preparation of pilocarpine and use thereof for treating eye diseases. The ophthalmic preparation of pilocarpine provided by the present application has the beneficial effects of good stability and less eye irritation.

The utility model relates to a lacrimal passage flushing auxiliary eyelid fixing tool which comprises an annular flexible eyeshade, and fixing structures used for fixing the annular flexible eyeshade to the eye socket position of a patient are installed at the two ends of the annular flexible eyeshade. Sliding sleeves are fixedly arranged on the upper side wall and the lower side wall of the annular flexible eyeshade in a penetrating mode, and pull rods are slidably connected into the sliding sleeves. When the eyeshade is used, the annular flexible eyeshade is worn at the eye socket position of a patient through the cloth belt, then the pull rod is pressed into the annular flexible eyeshade to extrude the spring to contract until the shifting plate installed on the metal reed moves to be aligned with the eyelids of the patient, then the screw is rotated to adjust the position of the metal reed so that the shifting plate can be attached to the eyelids of the patient, and the pull rod can be loosened. At the moment, the spring can push the pull rod to slide reversely under the action of elastic force, upper and lower eyelids of the patient are opened through the shifting plate, and the problem that operation of medical staff is affected due to frequent blinking of the patient caused by eye stimulation during lacrimal passage flushing of the patient is solved as much as possible.

The invention belongs to but not limited to the technical field of biological extraction, and discloses a high-activity eggshell membrane composite enzymatic hydrolysis extraction process and an extract, the process adopts a composite enzyme system of alkaline protease and papain for directional hydrolysis, and is combined with low-temperature ultrafiltration purification and freeze drying technologies, the total amount of amino acid in the obtained extract is greater than or equal to 79g / 100g, and the total amount of amino acid in the extract is greater than or equal to 79g / 100g. The sodium hyaluronate content is greater than or equal to 4.4 g / 100g, the collagen content is greater than or equal to 6.8%, the water solubility is greater than or equal to 95%, no skin and eye irritation is caused, the method can be widely applied to the fields of food health care, cosmetics, pet food and the like, the technical problems of loss of active ingredients and poor water solubility of a traditional process are solved, and the method is stable and controllable and suitable for industrial production. Through detection, the total amount of amino acid in the extract reaches 79.3 g / 100g, the content of sodium hyaluronate is 4.4 g / 100g, the content of collagen is 6.8%, and the extract is free of skin and eye irritation, can meet the application requirements in the fields of food health care, cosmetics and the like, is mature and controllable in process and is suitable for industrial large-scale production.

This invention relates to the field of traditional Chinese medicine antibacterial liquid technology, and particularly to a traditional Chinese medicine antibacterial liquid for nasal use, made from the following raw materials: Xanthium sibiricum, Centipeda minima, Magnolia biondii, Asarum heterotropoides, Acorus tatarinowii, Akebia trifoliata, Atractylodes lancea, Indigo naturalis, Mentha haplocalyx, and polyhexamethylene biguanide. This invention combines nine traditional Chinese medicines—Xanthium sibiricum, Centipeda minima, Magnolia biondii, Asarum heterotropoides, Acorus tatarinowii, Akebia trifoliata, Atractylodes lancea, Indigo naturalis, and Mentha haplocalyx—with polyhexamethylene biguanide. The traditional Chinese medicine components are an improvement on the ancient formula of Xanthium sibiricum powder, synergistically exerting the effects of clearing the lungs and nasal passages, dispelling wind and cold, and anti-inflammatory and anti-allergic properties. Polyhexamethylene biguanide provides broad-spectrum antibacterial efficacy. By changing the traditional oral dosage form to a nasal drop, the liquid acts directly on the nasal mucosa lesion site, avoiding the first-pass effect of the liver and the metabolic burden on the kidneys associated with oral medications, significantly improving drug safety. Skin irritation, eye irritation, and allergy tests all showed no irritation or sensitization.

The disclosure relates to formulations and methods for the in chemico testing of toxins based on a discovery that measuring a reduction in enzyme activity can be used to predict in vivo toxicity, including for example, a skin corrosion, skin irritation, eye corrosion, eye irritation, lung toxicity, liver toxicity, nervous system toxicity, developmental toxicity, acute toxicity etc. Disclosed methods are rapid, easy to perform and shelf-stable approaches for identification of toxic chemicals and materials.