Flavored dosage forms, e.g., lozenges and gums, are provided for sustained release of a flavoring agent in the mouth. The dosage forms provide sustained release by virtue of a wet matrix formed by admixture of a biocompatible, hydrophilic, water-insoluble
polymer such as ethylcellulose and a flavoring agent, particularly an
essential oil or a constituent thereof, e.g., a
terpene or
sesquiterpene. The dosage forms may also include a second beneficial agent in addition to the flavoring agent. Exemplary such beneficial agents include ionizable
zinc compounds and other cold remedies,
local anesthetic and anti-infective agents, diet aids,
fluoride-releasing compounds, and
nicotine. The dosage forms, when formulated as lozenges, may be somewhat
adhesive or substantially nontacky, depending primarily on the molecular weight of the hydrophilic
polymer.
Adhesive lozenges can serve as dosage forms that adhere to the teeth or gums for delivery of a beneficial agent thereto. Methods for using the dosage forms to provide sustained release of a flavoring agent and optionally deliver a second beneficial agent are also provided, as are methods for treating the
common cold, treating a
sore throat, facilitating
weight loss, and assisting in
smoking cessation.