The invention discloses a driver with a hydraulic tappet. The driver comprises a driver shell, a driving cylinder, a first piston, a second piston, a piston rod and the hydraulic tappet, wherein the hydraulic tappet further comprises a tappet plunger, a tappet body, a tappet high-pressure chamber, a tappet inflow channel, a discharge channel, a tappet one-way valve and a plunger return spring. The hydraulic tappet is optimized in design, and the driver with the hydraulic tappet has comprehensive advantages in terms of spatial size, high-pressure chamber pressure and cost, and is particularly applicable to valve clearance control of a variable valve driver. The hydraulic tappet is combined among the wall of the driving cylinder and the two pistons of the driver, the tappet body includes a tappet body end and a tappet body wall, the first piston serves as the tappet body end, the wall of the driving cylinder serves as the tappet body wall, so that the tappet high-pressure chamber can have a diameter as large as that of the driving cylinder to reduce the internal high pressure of the tappet high-pressure chamber, a normal air distribution function, low noise and reasonable service life are ensured, an additional tappet body wall structure and an additional high-precision matching structure are omitted, and manufacturing cost is reduced.