1 results about "Lactobacillus curvatus" patented technology

The present invention relates to an exosome-stabilized skin-improving cosmetic composition comprising a vitamin complex, which can improve the structural stability of exosomes. The composition comprises bone spicule, lactic acid bacteria exosome, and ceramide in a weight ratio of 0.6:3.0:0.01, the lactic acid bacteria exosome comprising a substance obtained by culturing Lactobacillus curvatus GFC-AM5 strain (deposited number KCCM12245P) at 37°C for 20 hours and concentrating it by 40 times or more. In addition, by including a vitamin complex of two or more selected from the group consisting of vitamin C or a derivative thereof, vitamin E or a derivative thereof, nicotinamide, and panthenol, oxidation of the lipid bilayer of the exosome can be inhibited, and the increase in particle size during storage can be reduced. Thereby, the structural integrity of the exosome can be maintained, thereby preserving the cell signaling function for a long time, and the stabilized exosome is delivered to the inside of the skin through the microchannels formed by the bone spicule, thereby effectively exerting a skin-improving effect.