5 results about "Memory retention disorder" patented technology

Disclosed are methods for assessing severity, determining future risk, matching with a drug treatment, and measuring response to treatment, for memory dysfunction, Alzheimer's disease, and cognitive decline. Also disclosed are new methods of use for drugs and natural compounds repurposed for use in improving memory, as well as for preventing and treating memory disorders, Alzheimer's disease and cognitive decline. All the above-mentioned methods are computer assisted methods analyzing the expression of panels of genes, clinical measures, and drug databases. A universal approach in everybody, as well as a personalized approaches by gender, and by diagnosis, are disclosed.

The present invention provides a novel memory disorder ameliorating agent. A PKC [gamma] activity inhibitor is useful as an active ingredient of a dysmnesia ameliorating agent.

The application provides a memory disorder evaluation system based on an electroencephalogram, comprising: a signal acquisition module configured to acquire an electroencephalogram of a target object; a preprocessing module configured to perform a band-pass filtering of 0.5Hz-40Hz on the electroencephalogram of the target object; a signal segmentation module configured to segment each channel and determine a plurality of non-overlapping Epochs corresponding to each channel; a feature extraction module configured to perform linear feature extraction and nonlinear feature extraction on each Epoch in each channel, and determine an electroencephalogram fusion feature of the target object based on the linear feature and the nonlinear feature of each Epoch; and a memory disorder evaluation module configured to input the electroencephalogram fusion feature into a trained memory disorder evaluation model, use the memory disorder evaluation model to evaluate the memory disorder of the target object, and obtain a memory disorder evaluation result of the target object. The scheme can efficiently evaluate the memory disorder of the target object.

The application belongs to an animal model, and aims to solve the technical problems that the evaluation method of the current Skinner box experimental data lacks a systematic experimental paradigm and evaluation means, and lacks related parameters, and provides an experimental animal learning and memory disorder model, a construction method and application. The traditional chronic social frustration model experiment process is optimized, the learning and memory disorder model of the mouse is stably induced, and the obtained experimental animal learning and memory disorder phenotype is obvious, and the diversity of stress-related disorder animal models is enriched. The learning and memory ability of the animal is evaluated by the Skinner box, the learning and memory related evaluation means is expanded, and new data support is provided for the construction and evaluation of the acute violent stress induced learning and memory disorder animal model.

The invention belongs to the technical field of essential oil, and particularly provides compound essential oil for improving learning and memory disorders as well as a preparation method and application of the compound essential oil. The liquid compound essential oil comprises the following raw materials in parts by weight: 30-40 parts of ginseng essential oil, 10-15 parts of rhizoma acori graminei essential oil, 1-5 parts of frankincense essential oil, 30-40 parts of perilla essential oil, 1-5 parts of borneol and 1-5 parts of ginkgo leaf essential oil. The compound essential oil for improving learning and memory disorders provided by the invention takes multiple traditional Chinese medicine extracts as raw materials, so that the compound essential oil has the effects of tonifying qi and inducing resuscitation, refreshing mind and restoring consciousness, soothing nerves and stabilizing mind and enhancing memory.