29 results about "Pathogen inactivation" patented technology

The invention provides a biological safe and efficient fattening field, and belongs to the technical field of livestock breeding. A negative pressure isolation belt is formed by the outer shell and the inner shell, so that external air is forced to flow through the visible light catalysis quantum dot layer to realize pathogen inactivation while the gas flow rate is controlled. An optical fiber sensing siphon is arranged below the slatted floor to monitor sewage pathogenic bacteria in real time. Live pigs enter the house through the third-stage buffer channel. The system breaks through the limitation of a traditional physical barrier, full-path blocking of a transmission chain of epidemic diseases such as African swine fever is achieved, and the biological safety level is improved by two orders of magnitude.

The present invention relates to a catalytic material with oxidant and / or acid-base properties, the preparation method thereof and the specific use thereof for pathogen inactivation. The invention also relates to a filter comprising the material.

The invention discloses an inactivation cabinet, which comprises a cabinet body, and a plurality of suspension supports arranged side by side and used for suspending a plurality of independent initial blood bags respectively are arranged in the cabinet body from top to bottom in sequence; the plurality of flow controllers are arranged side by side and are respectively used for adjusting the flow speeds of the plurality of blood treatment pipelines; the plurality of ultraviolet lamp boxes are arranged side by side and are respectively used for irradiating the plurality of blood treatment illumination plates; the shaking table is used for uniformly shaking the blood collection bag, and the initial blood bag is sequentially connected with a blood treatment illumination plate and the blood collection bag through the blood treatment pipeline. According to the invention, accurate temperature and ultraviolet irradiation dose control is carried out on to-be-treated blood through a software control system, so that a safe and efficient pathogen inactivation effect is achieved.

The invention relates to a pig manure rapid fermentation-soil remediation combined type complex microbial inoculant and application thereof.The complex microbial inoculant is formed by compounding bacillus subtilis, white rot fungi and trichoderma according to a specific proportion, and the bacillus subtilis strain is derived from an efficient compost isolate separated from composted pig manure compost. The microbial inoculum is prepared by adding the composite protective agent to be mixed with the carrier and performing low-temperature drying. During application, the pig manure is subjected to continuous high-energy quantum treatment, and pathogen inactivation and organic matter degradation are achieved through the synergistic effect of a high-frequency electric field and active particles; and then carrying out solid-liquid separation, inoculating the solid part with a complex microbial inoculant, carrying out short-period aerobic fermentation at 40-80 DEG C, and carrying out low-temperature airflow drying at 80-150 DEG C to prepare the solid organic fertilizer with both fertilizer efficiency and soil biocontrol function. And the liquid part is subjected to bipolar high energy quantum treatment and chemical neutralization to produce reclaimed water. Through systematic combination of high-energy quantum activation and the functional complex microbial inoculant, rapid and efficient fermentation and all-component resource utilization of pig manure are realized.

A method for producing an inactivated influenza vaccine by an egg culture method according to the present disclosure includes a pathogen inactivation step for inactivating pathogens mixed into an egg other than influenza viruses.

A control system and pathogen inactivation method to reduce cross-contamination within operational devices that experience sequential touching of touch spots on the operational device by multiple people. Additionally, the system controls and then executes the reconfiguration of touch spot position to increase the probabilistic time interval between sequential touches from a first person to a second person physically interacting with the operational device. The dynamic reconfiguration control system reduces the probability of cross-contamination between sequential personal touches in sequential user sessions.

This invention provides a method for preparing pathological sections of plague-affected experimental animals. The method includes the following steps: S1: sample pretreatment and fixation; S2: pathogen inactivation verification; S3: tissue dehydration, clearing, and paraffin embedding; S4: paraffin embedding; S5: sectioning and spreading; S6: staining; S7: mounting. The method for preparing pathological sections of plague-affected experimental animals provided by this invention has the advantages of ensuring absolute safety in the preparation process of high-risk pathogen sections through strict biosafety zoning and double inactivation verification, and obtaining high-quality pathological sections.

To provide a pathogen inactivation device that can suppress ineffective consumption of a radical and is excellent in energy efficiency of treatment, and a pathogen inactivation method.SOLUTION: A pathogen inactivation device 1 comprises: a plasma generation chamber 10; a high-voltage electrode 20 and a ground electrode 30 that are arranged opposite to each other at a distance within the plasma generation chamber 10; a flow rate adjustment 40 that adjusts a flow rate of plasma source gas flowing into the plasma generation chamber 10; a pressure reducing pump 50 and a pressure adjustment 60 that adjust the pressure in the plasma generation chamber 10 to a predetermined pressure; and a high voltage power source 70 that generates discharge plasma P between the high voltage electrode 20 and the ground electrode 30.SELECTED DRAWING: Figure 1

Provided are methods and systems for the pathogen inactivation of blood products and compositions, including methods of using devices (e.g., comprising component(s) configured to control flow of fluid(s)) to determine the amount of pathogen inactivation compound (PIC) necessary for pathogen inactivation of a blood composition (e.g., based at least in part on one or more input parameters) and allow transfer of the blood composition and the PIC into a container, e.g., of a processing set.

Provided are methods and systems for the pathogen inactivation of blood products and compositions, including methods of using devices (e.g., comprising component(s) configured to control flow of fluid(s)) to determine the amount of pathogen inactivation compound (PIC) necessary for pathogen inactivation of a blood composition (e.g., based at least in part on one or more input parameters) and allow transfer of the blood composition and the PIC into a container, e.g., of a processing set.

The invention relates to the technical field of medical waste treatment equipment, in particular to a medical mask recycling treatment machine. The invention provides a medical mask recycling treatment machine which comprises a treatment machine body, and a feeding hopper is arranged at the top of the treatment machine body; the interior of the treatment machine body is vertically divided into a crushing and preliminary disinfection area, a main disinfection area and a collection area which are sequentially arranged from top to bottom; a crushing roller and a disinfection air ejector are arranged in the crushing and preliminary disinfection area; a material storage plate capable of being opened and closed, an ultraviolet lamp and a fan are arranged in the main disinfection area; a material storage frame is arranged in the collecting area; and a control assembly is arranged on the processor body. According to the equipment, through the multi-stage assembly line design, crushing, retention and double disinfection of masks are achieved, sufficient crushing is guaranteed through the W-shaped baffle, disinfection dead angles are thoroughly eliminated through combination of ultraviolet rays and fan scattering, the pathogen inactivation rate is remarkably increased, and the risk of secondary pollution is fundamentally eradicated.

The invention discloses an application of a cationic polysaccharide photosensitizer as a blood pathogen inactivation material. The cationic polysaccharide photosensitizer has a repetitive structure unit as shown in a formula I. The invention further discloses a preparation method of the cationic polysaccharide photosensitizer. As an inactivator, the cationic polysaccharide photosensitizer can selectively recognize pathogens, efficiently generate ROS (reactive oxygen species) under illumination and kill the pathogens, and has important practical value.

The invention provides a silkworm excrement treatment device with negative pressure collection, which solves the pathogen diffusion and pollution problems of silkworm excrement stack retting through collaborative structural innovation: a stainless steel exhaust pipe vertically penetrates through the center of the top surface of a storage chamber and is connected with a gas treatment unit, namely an activated carbon canister for physically adsorbing pollutants, two 185nm ultraviolet lamp tubes are arranged in a UV disinfection cabin in parallel, and the ultraviolet lamp tubes are connected with the stainless steel exhaust pipe. A titanium dioxide catalysis net is filled in a gap of the lamp tube, a vacuum pump maintains negative pressure of-0.08 MPa to drive airflow to pass through directionally, and 99.97% inactivation rate of pathogens and removal rate of HS larger than 95% are achieved. The feeding hole rotary airtight valve is dynamically sealed through a silica gel sealing ring at the edge of a valve plate; and a trapezoidal silica gel gasket of the hydraulic sealing door of the discharge hole is precisely matched with a 15-degree conical flange surface after being pressed and expanded, so that a mechanical self-tightening zero-leakage barrier is formed. A temperature probe is pre-embedded in the 1 / 2 height of the side wall to monitor the core temperature of the pile body, a gas pressure sensor 10 cm below the top surface feeds back the gas state in real time, and the system is automatically adjusted to run in an over-limit mode.

A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles. Oxygen and pathogen reduced blood compositions comprising CPAD and riboflavin having reduced hemolysis. Oxygen and pathogen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles.

Materials with uniform electrostatic surface charge for antimicrobial pathogen inactivation while maintaining safety for use by individuals and workers (no cytotoxicity), as well as methods for making such antimicrobial materials and uses thereof.

A cell destruction method includes providing an anionic biomarker that comprises a magnetic material such as an iron or an iron compound. The anionic biomarker is introduced into an organism having pathogen cells with a negative charge. The anionic biomarkers are attracted to the negative charges of the pathogen and couple thereto. The anionic biomarker may also have a coupler portion that further aids in the anionic biomarker coupling to and being bound to the pathogen cell and / or cell wall. An electric field may be produced to cause the anionic biomarkers and / or the negative charges of the pathogen cell to polarize on or along the pathogen cell. A magnetic field is directed to cause the anionic biomarker, or magnetic material thereof to move and damage the cell. The magnetic field may be an alternating magnetic field that causes the magnetic material to oscillate and damage the cell wall.

The invention relates to a polyester fabric based on a zinc-based MOF (Metal Organic Framework) polymorphic nanostructure and a preparation method. The surface of the polyester fabric forms an MOF material with a polymorphic nanostructure through coordination of L-methionine and zinc ions. According to the invention, L-methionine is innovatively used as a bifunctional ligand, and a zinc-based MOF is anchored on the surface of an ammonolysis polyester fiber through a covalent bond, so that the polyester fabric with spectral pathogen inactivation capability is prepared. And the structure-function relationship between the zinc-based MOF polymorphic nanostructure and the pathogen inactivation efficiency is disclosed for the first time.

Methodology for increasing efficiency of a pathogen inactivation via enhancing UVC light absorption at such pathogen by multiple diffuse scattering of the light at a wall defining a substantially closed volume, thereby increasing a number of angles at which the pathogen is being irradiate as compared with a direct irradiation of the pathogen with a beam of such light.

The invention discloses a sewage disinfection online monitoring system applied to a shelter hospital, which comprises a pathogen inactivation verification module, a multi-parameter sensing module, a dynamic decision control module, a wireless ad hoc network deployment module and a safety compliance interaction module, the pathogen inactivation verification module outputs a real-time pathogen inactivation rate by using an optical signal generated by combining a gene engineering bacteriophage and a live pathogen, and the multi-parameter sensing module can synchronously collect residual chlorine concentration, sewage flow, pH value, water temperature and disinfection by-product spectral data; the dynamic decision control module can receive output data of the inactivation verification module and the sensing module. According to the invention, real-time monitoring and accurate control of the sewage disinfection process can be realized through cooperative work of multiple modules, the pathogen inactivation rate and various sewage parameters are acquired in real time by using genetic engineering bacteriophage and a multi-parameter sensing technology, and the disinfectant dosage is dynamically optimized through a deep learning model, so that the sewage disinfection efficiency is improved. The operation cost is reduced while the pathogen inactivation rate is greatly improved.

The embodiment is a morphologically active polymer comprising at least one pathogen binding site and where the morphologically active polymer, after binding the pathogen, changes at least its morphology, conformation, or configuration and inactivates the pathogen.

1. The name of the design product: blood monitor (filtering white blood cells / pathogen inactivation). 2. The use of the design product: used for the information management of the process of blood component preparation, blood leukocyte filtration, plasma virus inactivation, pathogen inactivation treatment. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: front view.

Method for increasing efficiency of a pathogen inactivation via enhancing UVC light absorption at such pathogen by multiple diffuse scattering of the light at a wall defining a substantially closed volume, thereby increasing a number of angles at which the pathogen is being irradiate as compared with a direct irradiation of the pathogen with a beam of such light.

The present disclosure provides compositions, methods, kits and systems for detecting antibodies in a biological sample. In some embodiments, methods / systems are particularly useful for detecting antibodies in patients against pathogen-inactivating compound treated RBCs.

An improved technology for inactivation of viruses, for example the SARS-COV-2 virus that is causing the Covid-19 pandemic, is described. The technology can include a device that includes a substrate coated in a polymer that is infused with a pathogen inactivating material. In various embodiments, at a given time, a portion of the pathogen inactivating material is exposed to the environment, and the device is configured to periodically or intermittently expose additional pathogen inactivating material to the environment. For example, the polymer can be ablative or sacrificial.

A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles. Oxygen and pathogen reduced blood compositions comprising CPAD and riboflavin having reduced hemolysis. Oxygen and pathogen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles.

This disclosure relates to a method for sanitizing a space. The method includes applying a composition containing triethylene glycol into a space containing a pathogen (e.g., a Staphylococcus, a Pseudomonas, a Listeria, Salmonella, Klebsiella, a mycobacterium, a mold, or a spore) in an amount effective to inactivate the pathogen.

Provided are methods for rapidly inactivating a pathogen, or for producing a vaccine composition containing an inactivated noninfectious pathogen having retained antigenicity and / or immunogenicity, comprising exposing the pathogen to a chemical inactivating agent (e.g., one or more chemical oxidizing, alkylating or crosslinking agents) in the presence of inorganic polyatomic oxyanions in an amount and for a time sufficient to render the pathogen noninfectious while enhancing retention of pathogen antigenicity and / or immunogenicity relative to that retained by contacting the pathogen with the chemical inactivating agent alone. The methods are broadly applicable to pathogens having RNA or DNA genomes (e.g., including viruses, bacteria, fungi, and parasites). Also provided are vaccine compositions (medicaments) containing a pathogen inactivated by exposure to an inactivating agent in the presence of elevated concentrations of inorganic polyatomic oxyanions, and methods for eliciting an immune response in a subject by administering the vaccine compositions.