The invention relates to a current peak detection device, a high voltage generator and vascular calcification treatment equipment. The current peak detection device comprises a PCB Rogowski coil, a sampling resistor, a signal amplification circuit, an integration and voltage holding circuit and a microcontroller, wherein the PCB Rogowski coil is used for sensing a current signal in a circuit to be detected and obtaining a corresponding induced electromotive force; the sampling resistor is connected with the PCB Rogowski coil, the signal amplification circuit is connected with the sampling resistor, the integration and voltage holding circuit is connected with the signal amplification circuit; the microcontroller is connected with the integration and voltage holding circuit and used for conducting ADC sampling on the maximum value of a voltage signal, and the current peak value of the current signal in the circuit to be detected is obtained according to the ADC sampling data and preset current calibration data. According to the invention, real-time monitoring of the pulse current can be realized, the current peak value of the pulse current can be accurately detected, an original high-voltage discharge loop is not influenced, and the device has the advantages of high safety, fast response speed, stable process, high consistency and low cost.